Publications by authors named "Chengxin Fan"

In light of the ERI exacerbated by health emergencies, stabilizing the working conditions of primary healthcare professionals and ensuring the consistent operation of the public health system has become a focal point of research. This study was designed to investigate the mechanisms by which ERI affects job performance among primary healthcare professionals in the context of health emergencies, as well as the mediating role of perceived social support and resilience. Participants were recruited from 54 primary healthcare institutions, with a total of 1,050 primary healthcare professionals included in the study.

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Background: Traditional Chinese medicine plays a unique role and has proven efficacy in preventing and treating common and chronic diseases. Moxibustion, as a type of traditional Chinese medicine healthcare therapy, has a broad mass, social, and cultural foundation in China. This study analyzes the pathways and influencing factors of residents' acceptance of moxibustion.

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Background Data on persistent use of HIV pre-exposure prophylaxis (PrEP) is limited among Chinese men who have sex with men (MSM). This study aimed to explore factors associated with the re-initiation of PrEP among Chinese MSM from a longitudinal PrEP demonstration trial. Methods A multi-center cohort study was conducted in Guangzhou and Wuhan, China (September 2021-2024), providing 1134 MSM participants with a 12-month dosage of tenofovir disoproxil fumarate and emtricitabine (TDF/FTC) as oral PrEP.

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Peer referral leverages social networks to connect individuals with health services, potentially enhancing pre-exposure prophylaxis (PrEP) use. This study aims to investigate the impact of peer referral on PrEP adherence and persistence among men who have sex with men (MSM) in China. This study is nested in a 12-month PrEP (FTC/TDF) demonstration trial in China from September 2021 to December 2023.

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Background: Point-of-care (PoC) hepatitis B virus (HBV) DNA viral load (VL) assays represent an alternative to laboratory-based standard-of-care (SoC) VL assays to accelerate diagnosis and treatment. We evaluated the impact of using PoC versus SoC approaches on the uptake of VL testing, treatment, and turnaround times from testing to treatment across the HBV care cascade.

Methods: We searched 5 databases, 6 conference websites, and contacted manufacturers for unpublished reports, for articles with or without a comparator (SoC VL testing), and had data on the uptake of VL testing, treatment, or turnaround times between hepatitis B surface antigen (HBsAg) testing, VL testing, and treatment in the cascade.

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Article Synopsis
  • The study addresses the growing public health issue of herpes simplex type 2 (HSV-2) infections in China, highlighting the need for better intervention strategies based on epidemiological data.
  • A systematic review of 23,999 articles resulted in 402 publications being analyzed, revealing a general HSV-2 seroprevalence of 7.7%, with higher rates among intermediate-risk (14.8%) and key populations (31.7%), particularly among female sexual workers.
  • Findings indicate significant regional disparities in HSV-2 prevalence, with northeastern China having higher rates, and a notable difference in prevalence estimates between Chinese and English publications among key populations.
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Introduction: Social network strategies, in which social networks are utilized to influence individuals or communities, are increasingly being used to deliver human immunodeficiency virus (HIV) interventions to key populations. We summarized and critically assessed existing research on the effectiveness of social network strategies in promoting HIV self-testing (HIVST).

Methods: Using search terms related to social network interventions and HIVST, we searched five databases for trials published between 1st January 2010 and 30th June 2023.

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Healthcare disparities are common among people living with HIV (PLWH) in China and likely impact access to HIV services. This study aimed to assess the current status of access to HIV services among PLWH and explore the correlates of service uptake using baseline data from a prospective cohort study among PLWH in Jiangsu Province. Guided by Andersen's behavioral model, univariable and multivariable logistic regressions were conducted to identify factors associated with access to HIV services.

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Introduction: Social network strategies, in which social networks are utilized to influence individuals or communities, are increasingly being used to deliver human immunodeficiency virus (HIV) interventions to key populations. We summarized and critically assessed existing research on the effectiveness of social network strategies in promoting HIV self-testing (HIVST).

Methods: Using search terms related to social network interventions and HIVST, we searched five databases for trials published between January 1, 2010, and June 30, 2023.

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Background: This review aims to assess the status of healthcare disparities among people living with HIV (PLWH) in China and summarize the factors that drive them.

Methods: We searched PubMed, Web of Science, Cochrane Library, Scopus, China National Knowledge Infrastructure (CNKI) and China Wanfang for studies published in English or Chinese. Studies focusing on any disparities in healthcare services among PLWH in China and published between January 2000 and July 2022 were included.

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Background Healthcare disparities hinder the goal of ending the HIV pandemic by 2030. This review aimed to understand the status of healthcare disparities among people living with HIV (PLWH) in China and summarize driving factors. Methods We searched six databases: PubMed, Web of Science, Cochrane Library, Scopus, China National Knowledge Infrastructure (CNKI), and China Wanfang.

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Clean soil is a potential capping material for controlling internal nutrient loading and helping the recovery of macrophytes in eutrophic lakes, but the long-term effects and underlying mechanisms of clean soil capping under in-situ conditions remain poorly understood. In this study, a three-year field capping enclosure experiment combining intact sediment core incubation, in-situ porewater sampling, isotherm adsorption experiments and analysis of sediment nitrogen (N) and phosphorus (P) fractions was conducted to assess the long-term performance of clean soil capping on internal loading in Lake Taihu. Our results indicate that clean soil has excellent P adsorption and retention capacity as an ecologically safe capping material and can effectively mitigate NH-N and SRP (soluble reactive P) fluxes at the sediment-water interface (SWI) and porewater SRP concentration for one year after capping.

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Background: Population migration in China has increasingly included middle-aged and older populations. Relatedly, the lack of mental health education among China's older migrants is still an important but neglected problem. This study aimed to understand the current situation of mental health education received by the older migrant population in China and to explore related influencing factors.

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Background: Village doctors in China are not only the gatekeepers of rural residents' health but also the net bottom of the medical security system. However, emotional labour is increasingly threatening the stability of the rural primary medical system. In addition, the ongoing coronavirus disease 2019 (COVID-19) pandemic has further exposed the vulnerability of human resources in China's rural health system.

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Heavy metal pollution in sediments is a common environmental issue in small- and medium-sized reservoirs not only in China but also worldwide; however, few interpretations of the pollution pattern exist. Based on the analyses of accumulation characteristics, ecological risks, and source apportionments of eight heavy metals (As, Cd, Cr, Cu, Hg, Pb, Ni, and Zn) in sediments, we derived a paradigm to describe the pollution pattern of heavy metals in sediments of a typical small- and medium-sized Tongjiqiao Reservoir. The results showed high levels of Cd, Hg, and As pollutants in the surface and upper sediment layers of the pre-dam area.

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Background: Primary healthcare professionals were overworked and psychologically overwhelmed during the COVID-19 pandemic. Resilience is an important shield for individuals to cope with psychological stress and improve performance in crises. This study aims to explore the association of individual resilience with organizational resilience, perceived social support and job performance among healthcare professionals in township health centers of China during the COVID-19 pandemic.

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Sediment is an important source of matter that causes blackening and odor formation in a water body. The restoration of polluted sediment can suppress algae-induced black blooms to a certain degree. In this study, we compared the control effects of sediment dredging and capping with clean soil on algae-induced black blooms in Lake Taihu using indoor simulation experiments.

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Background: The COVID-19 outbreak has tremendously impacted the world. The number of confirmed cases has continued to increase, causing damage to society and the economy worldwide. The public pays close attention to information on the pandemic and learns about the disease through various media outlets.

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Internal nitrogen (N) loading of lakes is commonly controlled by sediment dredging, although its comprehensive effect on internal N loading remains unclear. Herein, we examined the long-term effects of sediment dredging on internal N loading from a new perspective on the N budget at the sediment-water interface (SWI) through a simulation of field dredging performed by incubating intact sediment cores from a shallow eutrophic lake (Lake Taihu). We further evaluated the role of settling particles (SP) in the recovery of N cycle processes after dredging and its potential impact on the N budget.

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Sediment dredging is an effective method to reduce internal phosphorus (P) loading of eutrophic lakes. However, external P loading may diminish the longevity of the effect of sediment dredging on P internal loading, and the mechanism of the same is unclear. Here, we used one-year in-situ simulation experiments to study the migration and transformation processes of P under the effect of external loading (suspended particle matter, SPM) input and internal loading control by dredging.

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Environmental sediment dredging is one of the most common methods for the remediation of contaminated sediments in lakes; however, debate continues as to whether the effectiveness of dredging methods contributes to this phenomenon. To determine sediment resuspension and nutrient release following dredging with a variety of dredging methods, four dredging treatments at wind speeds of 0-5.2 m/s were simulated in this study, namely suction dredging (SD), grab dredging (GD), ideal dredging with no residual sediments (ID), and non-dredging (ND).

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Dredging is widely applied to remediate contaminated sediments in aquatic ecosystems. However, the efficiency of thin-layer dredging for metal pollution control remains uncertain and even controversial. This study conducted an in-situ simulation experiment in Lake Taihu to investigate dredging effects on sediment metal release based on metal fractions, diffusion flux and kinetics parameters of metal resupply, using diffusive gradient in thin films (DGT), multi-microelectrode, and European Community Bureau of Reference (BCR) sequential extraction scheme.

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Dredging is frequently implemented for the reduction of internal nitrogen (N) and phosphorus (P) loadings and the control of eutrophication. Residuals during dredging activities and external pollution loadings after dredging both commonly contribute to influence the effectiveness of dredging and have been widely discussed. In the current study, the exchanges of N and P across the sediment-water interface (SWI) to these two factors were compared in a six-month field incubation experiment.

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A year-long field investigation was carried out in the most heavily polluted bay of Lake Chaohu to assess the temporal exchanges of ammonium nitrogen ( View Article and Find Full Text PDF

In eutrophic lake restorations, in situ capping is an often considered method to control sediment internal phosphorus (P) pollution for mitigating eutrophication status. Subsequent aquatic macrophyte revegetation can directly derive P from the sediment for growth. However, the effects of capping with clean soils on internal P release from sediments under rooted aquatic macrophyte revegetation are still unclear.

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