Psychoacoustic assessment of misophonia.

Misophonia is a condition characterized by intense negative emotional reactions to trigger sounds and related stimuli. In this study, adult listeners (N = 15) with a self-reported history of misophonia symptoms and a control group without misophonia (N = 15) completed listening judgements of recorded misophonia trigger stimuli using a standard scale. Participants also completed an established questionnaire of misophonia symptoms, the Misophonia Questionnaire (MQ).

The effects of brines relevant to Mars and the ocean worlds on bacterial growth reflect salt-specific responses across water activity.

Freezing point depression due to high salt concentration is crucial for liquid water to exist on cold worlds, expanding special regions where habitats are plausible. Determination of the growth tolerances of terrestrial microbes in analog systems impacts planetary protection protocols aimed at preventing interference with life detection missions or potential native ecosystems on celestial bodies. We measured the salinity tolerances of 18 salinotolerant bacteria (Bacillus, Halomonas, Marinococcus, Nesterenkonia, Planococcus, Salibacillus, and Terribacillus).

Self-Transcendence, Diabetes Self-Care, and Well-Being of Emerging Adults with Type 1 Diabetes.

Emerging adults with type 1 diabetes (T1D) are vulnerable to diabetes distress, decreased diabetes self-care, and decreased well-being due to simultaneously managing complex self-care demands and meeting developmental goals. Self-transcendence is an inherent human process that helps to mitigate vulnerability and promote a sense of well-being. The purpose of this qualitative descriptive study was to describe the perspectives and behaviors of emerging adults with T1D that reflected self-transcendence and how this process facilitated their diabetes self-care.

Examining for race-associated differences on Sway Medical System balance and cognitive tests used for sport-related concussion.

Background: Race associated differences and disparities in test scores, such as on neuropsychological measures, can complicate the interpretation of these test scores in student athletes following a concussion. It is unknown if there are race associated differences on the Sway Medical System, a battery that includes balance and cognitive tests for use in concussion management.

Purpose: To determine if there are race-associated differences in Sway Medical System balance and cognitive module scores among athletes undergoing preseason baseline testing.

Multimodal deep learning for predicting protein ubiquitination sites.

Motivation: Ubiquitination is a crucial post-translational modification that regulates various biological functions, including protein degradation, signal transduction, and cellular homeostasis. Accurate identification of ubiquitination sites is essential for understanding these mechanisms, yet existing prediction tools often lack generalizability across diverse datasets. To address this limitation, we developed Multimodal Ubiquitination Predictor, a deep learning-based approach capable of predicting ubiquitination sites across general, human-specific, and plant-specific datasets.

Exposure to Mitochondrial Toxins: An In Vitro Study of Energy Depletion and Oxidative Stress in Driving Dopaminergic Neuronal Death in MN9D Cells.

Mitochondrial dysfunction is a key contributor to neurodegeneration, particularly in Parkinson's disease (PD), where dopaminergic neurons being highly metabolically active are vulnerable to oxidative stress and bioenergetic failure. In this study, we investigate the effects of rotenone, a Complex I inhibitor, and antimycin A, a Complex III inhibitor, on mitochondrial function in MN9D dopaminergic neuronal cells. Cells were treated with rotenone (1.

Use Challenges and Training Needs of In-Vehicle Technologies for Older Drivers With Vision Impairments.

Importance: Older drivers with impaired vision may face challenges using in-vehicle technologies, affecting user experience.

Objective: To explore use challenges with in-vehicle technologies and training preferences of older drivers with and without central vision loss (CVL).

Design: A telephone questionnaire on perceptions of driver-vehicle interface use difficulties, challenges with existing advanced driver assistance systems (ADAS), and preferences for ADAS acquisition and training.

Central and peripheral fatigue indices following resistance exercise with and without blood flow restriction among people with multiple sclerosis.

Muscle fatigue is a prevalent and challenging symptom in people with multiple sclerosis (PwMS), typically involving pronounced central (e.g., reduced corticospinal excitability) and relatively lower peripheral contributions (e.

The Single-Leg Wall Squat Test: An Assessment of Functional Lower Extremity Endurance in University Students.

Background: The single-leg wall squat (SLWS) has the potential to be used as a functional test to assess lower extremity muscular endurance. While previous research has explored its muscular activation patterns, its relationship with isolated muscle strength and potential sex-specific responses remains under-investigated.

Purpose: This study aimed to examine the descriptive statistics of the SLWS and the correlation between handheld dynamometry (HHD) measures of hip and knee strength and SLWS test performance.

Acceptance and Commitment Therapy for Depression.

Outcome research on the efficacy of acceptance and commitment therapy (ACT) has established it as an evidence-based cognitive-behavioral approach in treatment of depression. Mediational and related research, however, has provided mixed support for the sensitivity and specificity of ACT's purported processes of therapeutic change according to model of psychological flexibility on which it is based. Whether an emerging idionomic approach to process-based interventions, such as ACT for depression that is more tailored to the lived experiences of individual clients enhances its efficacy, while also providing a more coherent understanding of its mechanisms of action, is currently an unanswered empirical question.

Psychometric Properties of the Self-as-Context Scale with a University Counseling Center Sample.

The model upon which acceptance and commitment therapy is based posits that its outcomes are mediated by increased psychological flexibility as a core process. Of the six subprocesses contributing to psychological flexibility, self-as-context has been investigated the least due to a lack of adequate assessment. An evaluation of the psychometric properties of at least one such measure-the Self-as-Context Scale (SACS)-has been primarily limited to nonclinical populations.

QRS 3D voltage-time integral in narrow QRS complex - Establishing the normal reference range.

Background: Vectorcardiographic 3D QRS voltage-time integral (VTI) is a novel marker of ventricular dyssynchrony pertinent for cardiac resynchronization therapy. It may have additional clinical utility but its normal reference ranges have not been established. We sought to define reference ranges for VTI in healthy individuals.

Measurement Along the Path of Unmanned Aerial Vehicles for Best Horizontal Dilution of Precision and Geometric Dilution of Precision.

In the zenith-horizon placement for achieving minimum geometric dilution of precision (GDOP), one access node or sensor is positioned along the z-axis, while the remaining nodes are placed symmetrically on a three-dimensional (3D) cone. This configuration yields the minimum GDOP at the cone's tip, which we term the designated min-GDOP point. However, in practical localization applications, the unknown node is not necessarily located at this designated min-GDOP point; instead, it may be situated anywhere within an area.

Examination of neuromuscular and tissue oxygenation characteristics during submaximal treadmill running with blood flow restriction.

Purpose: The use of blood flow restricted (BFR) running may provide an alternative to lower the running speed without compromising physiological responses that often occur during high intensity running. The purpose of this investigation was to compare the acute effects of various submaximal treadmill running speeds with BFR relative to maximal treadmill running speed without BFR on surface electromyographic amplitude (sEMG), surface electromyographic mean power frequency (sEMG), and muscle tissue oxygenation (StO) responses.

Methods: Thirteen college-aged females randomly completed four, three-minute treadmill running bouts at 70%, 80%, and 90% of their top speed (achieved during a graded exercise test) with BFR (70%, 80%, and 90%) and 100% of their top speed without BFR (100%).

Family Socioeconomic Status in Adolescence and Gender Identification in Emerging Adulthood.

This study contributes to research exploring social factors shaping gender identification. Informed by structural symbolic interactionism, social identity theory, and Levitt's psychosocial theory of gender, we explore how a key aspect of external social structure-adolescent family socioeconomic status-is associated with gender identification in emerging adulthood. We examine whether correlates of family socioeconomic status, including adolescent family and educational experiences and friend and high school characteristics, are associated with a cisgender, binary transgender, nonbinary, or gender unsure identification.

Aberrant neural activation during inhibitory control in girls with fragile X syndrome.

Fragile X syndrome (FXS) is a genetic condition associated with risk for deficits in executive function, especially response inhibition. Under a clinical setting, this study employs a mobile neuroimaging technique, functional near-infrared spectroscopy (fNIRS), to examine differences in inhibition-elicited neural activation between girls with FXS and a control group matched for age, cognitive function, and clinical symptoms. fNIRS data were collected from 42 girls with FXS and 31 controls during a go/nogo task, with valid data available from 35 and 30 respectively.

Lessons Learned from a Grassroots Harm Reduction Effort to Prevent Drug Overdose Deaths.

Inequities with access to naloxone and fentanyl test strips (FTS) due to cost and stigma have reinforced the necessity of community-based distribution of lifesaving harm reduction supplies. In Wichita and Sedgwick County, the epicenter of the opioid epidemic in Kansas, Safe Streets Wichita, a grassroots prevention and harm reduction coalition, started Project Wichita Overdose Recovery Kit Expedited Delivery (WORKED), a free volunteer-led intramuscular naloxone and FTS program. To assess the lessons learned from those involved with Project WORKED, interviews with 12 key stakeholders were conducted.

Comparable muscle fatigue responses across different low-load blood flow restriction protocols among women.

Purpose: Low-load blood flow restricted (LLBFR) resistance exercise has been demonstrated to accelerate acute muscle fatigue, but these responses may be dependent upon the protocol used. The purpose of this investigation was to examine fatigue characteristics following acute LLBFR resistance exercise with a 75-repetition (75-rep; 1 × 30, 3 × 15), 3 sets to failure (3×), and 1 set to failure (1×) protocols.

Methods: Sixteen women randomly performed 75-rep, 3× , and 1× LLBFR protocols consisting of unilateral, submaximal (30% of maximal voluntary isometric contraction; [MVIC]), isokinetic (90°·s), leg extension muscle actions.

The Formal EU-US Meniscus Rehabilitation 2024 Consensus: An ESSKA-AOSSM-AASPT Initiative Part II-Prevention, Nonoperative Treatment and Return to Sport.

Purpose: Part II of this consensus aimed to provide recommendations for the prevention of meniscus injuries, nonoperative treatment of acute tears and degenerative lesions, return to sports and patient-reported outcome measures.

Methods: This consensus followed the European Society of Knee Surgery, Sports Traumatology and Arthroscopy (ESSKA) formal consensus methodology. For this combined ESSKA-American Orthopedic Society for Sports Medicine (AOSSM)-American Academy of Sports Physical Therapy (AASPT) initiative, 67 experts from 14 countries, including orthopedic surgeons and physiotherapists, were involved.

The formal EU-US Meniscus Rehabilitation 2024 Consensus: An ESSKA-AOSSM-AASPT initiative. Part II-Prevention, non-operative treatment and return to sport.

Purpose: Part two of this consensus aimed to provide recommendations for the prevention of meniscus injuries, non-operative treatment of acute tears and degenerative lesions, return to sports and patient-reported outcome measures.

Methods: This consensus followed the European Society of Knee Surgery, Sports Traumatology and Arthroscopy (ESSKA) formal consensus methodology. For this combined ESSKA-American Orthopedic Society for Sports Medicine (AOSSM)-American Academy of Sports Physical Therapy (AASPT) initiative, 67 experts from 14 countries, including orthopedic surgeons and physiotherapists, were involved.

Prioritizing organizational success and the pursuit of victory: Understanding the feelings of exclusion in the workplace.

This study investigates how an organizational bottom-line mentality (BLM) climate influences employee perceptions of workplace ostracism, with a focus on the moderating role of zero-sum beliefs (ZSB). Using a survey of 220 full-time respondents in the United States, we conducted regression analysis and moderated mediation tests via Hayes' PROCESS macro in R. We measured perceived organizational BLM, employee BLM, ZSB, and work ostracism using validated scales.

Turning the Page: Midwest SLPs' Lived Experiences Providing Literacy Services in Schools.

School-based speech-language pathologists (SLPs) from four midwestern states were surveyed about their knowledge and confidence regarding literacy intervention. To obtain accounts of lived experiences, SLPs who completed the survey were invited to a follow-up interview. Fourteen SLPs completed interviews with a member of the research team via a recorded Zoom meeting.

Improved Hip Flexibility and Gluteal Function Following a Daily Lunge-and-Reach Stretching Intervention.

Background: A sedentary lifestyle contributes to hip flexor tightness. Some evidence suggests that tight hip flexors may contribute to impairments in gluteal function.

Purpose: The purpose of this study was to determine the effects of a daily lunge-and-reach stretching program on hip flexor length and gluteus maximus strength, power, and endurance in healthy college-aged adults.

The effectiveness of a geriatric simulation suit for improving empathy and simulating the aging process for older adults in a DPT program: a pilot study.

Enhancing empathy toward older adults among physical therapy students is essential to prepare graduates to be equipped to properly treat geriatric patients in all types of healthcare settings. This pilot study evaluated the effectiveness of a homemade geriatric suit to simulate an older adult and improve empathy among physical therapy students. The Jefferson Scale of Empathy for Health Professions student version was utilized to measure empathy-related parameters before and after the geriatric simulation experience.