The Scissors Effect of the Macromolecular Crosslinker on the Glass Transition of Polystyrene in Its Conetworks with Poly(dimethylsiloxane).

The glass transition temperature () is undoubtedly one of the most important characteristics of polymers, and investigating its dependence on their structure and composition is crucial from both fundamental and application points of view. This study deals with the unexpected relationship between and the average molecular weight between crosslinking points () in nanophase-separated polystyrene--poly(dimethylsiloxane) (PSt--PDMS) and polystyrene--poly(dimethylsiloxane)/divinylbenzene (PSt--PDMS/DVB) polymer conetworks. In order to reveal the correlation between the and , a library of PSt--PDMS and PSt--PDMS/DVB conetworks was synthesized, and their compositions and s were determined.

Epidemiological, Clinical, and Molecular Insights into Canine Distemper Virus in the Mekong Delta Region of Vietnam.

Canine distemper virus (CDV) is a highly contagious pathogen and causes a fatal systemic disease in domestic dogs and wild carnivores worldwide. Despite CDV infections being monitored globally, studies on CDV in Vietnam seem to be limited. This study, therefore, investigated the epidemiological, clinical, and molecular characteristics of CDV in the Mekong Delta (MD) region of Vietnam.

Application of Response Surface Methodology for the Optimization of Basic Red 46 Dye Degradation in an Electrocoagulation-Ozonation Hybrid System.

The release of synthetic dyes like Basic Red 46 (BR46) from industrial wastewater has raised growing concerns due to their toxicity, long-term persistence, and resistance to standard biological treatment methods. In this work, we developed and tested a pilot-scale electrocoagulation-ozonation (EC-O) hybrid system aimed at removing BR46 from aqueous solutions. The system integrates electrocoagulation, using iron electrodes, with ozone-based advanced oxidation processes, facilitating a combination of coagulation, adsorption, and oxidative breakdown of dye molecules.

Iridium-free high-entropy ruthenium-based oxides with activated lattice oxygen towards high efficient and durable acidic water oxidation.

Ruthenium-based oxides are promising high-activity acidic OER catalysts to replace IrO but suffer from poor stability. Here, we report an Ir-free high-entropy (RuCrMnFeNi)O electrocatalyst with exceptional activity (212 mV@10 mA cm) and stability (100 h) in 0.5 M HSO.

Improvement in Transient Agarose Spot (TAS) Cell Migration Assay: Microplate-Based Detection and Evaluation.

Collective cell migration is crucial in various biological processes, including tumor progression and metastasis. The widely used scratch assay (wound healing assay) has limitations in throughput, reproducibility, and data analysis. To overcome these challenges, we previously developed the Transient Agarose Spot (TAS) assay, which enhanced assay precision and reproducibility.

Comprehensive Risk Evaluation of Perfluoroalkyl Substance Pollution in Urban Riverine Systems: Ecotoxicological and Human Health Perspectives.

This study investigated the spatiotemporal distribution of perfluoroalkyl substances (PFASs) in the Daku River, Taoyuan, with a particular focus on source apportionment and associated ecological and human health risks. The total PFAS concentrations ranged from below the detection limits to 185 ng/L, with perfluorooctanoic acid (PFOA) emerging as the predominant compound, followed by perfluorobutanesulfonic acid (PFBS). Elevated PFAS levels were observed downstream of the confluence between the Daku River and Litouzhou ditch, suggesting contributions from industrial activities.

Design, synthesis and computational approach of vanillyl-imidazolidinyl-sulfamethoxazole derivatives as potent antimicrobial candidates tackling microbial resistance.

Superbugs are dominating the world due to the misuse and overuse of antibiotics. This study designed and synthesised two sets of compounds, oxazolones (3a-3j) and their respective imidazolones (4a-4j) bearing a sulfonamide functional group, with increased efficacy and capability to tackle microbial resistance. The structural conformation of compounds was determined using different techniques, including H/C NMR, FT-IR, HRMS and elemental analysis.

Weyl Semimetals: From Principles, Materials to Applications.

Weyl semimetals have attracted significant interest in condensed matter physics and materials science, due to their unique electronic and topological properties. These characteristics not only deepen the understanding of fundamental quantum phenomena, but also make Weyl semimetals promising candidates for advanced applications in electronics, photonics, and spintronics. This review provides a systematic overview of the field, covering theoretical foundations, material synthesis, engineering strategies, and emerging device applications.

Not just old wine in new bottles: Polygenic liability for ADHD is associated with electrophysiological affective-motivational processing beyond anxiety, depression, and ODD.

In attention-deficit/hyperactivity disorder (ADHD), emotional features account for heterogeneity and exacerbate severity of behavioral and functional impairments, beyond cognitive and comorbidity features. Yet, debate remains about the extent to which, in ADHD, such emotional features are a "core feature", i.e.

Near-Wavelength Sculpturing-Evoked Radiative Cooling.

Radiative cooling, inspired by the silver ants of the Sahara Desert, is gaining increasing interest for its cost-effectiveness and zero energy consumption. However, it remains imperative and challenging to deal with high-temperature environments, which are inevitably required in many cutting-edge applications. We proposed the direct femtosecond laser sculpturing of near-wavelength microgrooves on substrates to evoke powerful radiative cooling.

Bridging the divide: Cultivating collaborative leadership in a rural Ghanaian school.

This study examines administration-faculty relationships at Chiana Senior High School (SHS) in Ghana, highlighting challenges in communication, cultural sensitivity, decision-making, and professional development. Using a mixed-methods approach, findings reveal that 75.6 % of faculty feel their concerns are unaddressed while communication channels exist.

Mn-Co-BTC@MOF/S-MXene composite with superior efficiency for Pb(II) ion removal: Mechanistic and DFT study.

The increasing severity of water pollution requires effective remediation solutions. In this study, a Mn-Co-BTC@MOF/S-MXene composite was synthesized and characterized by variety of analytical tools including FTIR, XPS, XRD, SEM, and Zeta Potential to confirm its successful fabrication. Zeta potential clarified that Mn-Co-BTC@MOF/S-MXene has a point of zero charge of 3.

Epistemic preparedness.

Preparedness strategies for emergent infectious diseases have focused on microbial surveillance, medical stockpiling and healthcare infrastructure resilience. But what does it mean to be or cognitively prepared for the next disease outbreak? Taking stock of lessons for data practices and statistical modelling in the wake of COVID-19, we propose a reconceptualising of preparedness in global health, focusing on ecological and sociological configurations or framings rather than resorting to reductive 'crisis technologies'. We address three problem areas: data collection and sharing, outbreak modelling and the spatiotemporal structuring of analysis and intervention.

Explainable artificial neural network as a soft sensor to predict the moisture content in a continuous granulation line.

The application of artificial neural networks (ANNs) has the potential to fundamentally change the pharmaceutical industry, making manufacturing more agile, robust, efficient and reliable. Although ANNs' application as data-driven soft sensors has a particular potential, the black-box nature of most models creates mistrust and prevents their widespread application. Therefore, this study focuses on the development of an explainable ANN used as a soft sensor to monitor an integrated, continuous manufacturing process based on twin-screw granulation.

Future of diabetic foot risk: Unveiling predictive continuous glucose monitoring biomarkers.

This study critically analyzes the findings of Geng , which investigated the association between continuous glucose monitoring (CGM) metrics and the risk of diabetic foot (DF) in individuals with type 2 diabetes mellitus. The study demonstrated significant associations between lower time in range, higher glycemic risk index, mean blood glucose, and time above range and an increased risk of DF. While acknowledging the study's strengths, such as its large sample size and robust statistical methods, this analysis also highlights its limitations, including its cross-sectional design and reliance on self-reported data.

Beyond association: Examining overweight as a mediator in the link between depression and diabetes.

This letter critically examines a recent study by Zhang investigating the mediating role of overweight in the association between depression and new-onset diabetes among middle-aged and older adults. The study provides compelling evidence that overweight mediates approximately 61% of this relationship, suggesting that depression may contribute to diabetes by influencing behaviors that lead to weight gain. This aligns with the understanding that depression can impact appetite regulation and physical activity.

Expert-level differentiation of incomplete Kawasaki disease and pneumonia from echocardiography via multiple large receptive attention mechanisms.

Background: Incomplete Kawasaki disease (KD) is challenging to diagnose due to its lack of classic clinical features, yet it has a higher incidence of coronary artery lesions, making early detection crucial. Echocardiography plays a vital role in identifying these lesions, but differentiating incomplete KD from other febrile illnesses, such as COVID-19, is difficult. Algorithms capable of achieving expert-level performance are needed to aid diagnosis, particularly in the absence of pediatric cardiologists.

Optimizing wound healing: insights from phytochemicals and advanced therapies.

Wound healing is a complex process with various dimensions, often presenting as a growing concern that prompts the quest for advancements. This review emphasizes the therapeutic potential of medicinal plants rich in flavonoids, terpenoids, polyphenols, alkaloids, and steroids and discusses their valuable antibacterial, antioxidant, and anti-inflammatory properties in wound management. Cross talk of the phytochemicals with the intricate phases of wound healing, encompassing hemostasis, inflammation, proliferation, and remodeling is detailed, highlighting essential cellular and molecular mechanisms crucial for effective tissue repair.

Recovering the polyhedral geometry of fragments.

Not only is the geometry of rock fragments often well approximated by convex polyhedra having few faces and vertices, but these numbers carry vital geophysical information on the fragmentation process. Despite their significance, the identification of the number of faces and vertices of the ideal polyhedron has so far been carried out only through visual inspection. Here, we present an algorithm capable of performing this task in a reliable manner.

Amlodipine protects the retinal ganglionic cell damage maintaining intra ocular pressure by regulating the biological activities of carrageenan like red algae: an in vivo and in-silico study.

Unlabelled: Carrageenan (Carr), a natural polysaccharide derived from edible red algae, was used for the green biosynthesis and also recognized as toxic compound causing oxidative stress. The objective was to know the insight mechanism of Carr-induced retino ganglionic cell (RGCs) damage and its connection with brain having two model systems, mammalian (rabbit), lower vertebrates (zebrafish). The present study investigated the modulatory effect of amlodipine (AML), a dihydropyridine calcium channel antagonist, against Carr-induced RGCs loss.

Graphene oxide-carbon nanotube-magnetite nanocomposites for efficient arsenic removal from aqueous solutions.

In this study, graphene oxide-carbon nanotube-magnetite (GO/CNT/FeO) nanocomposites were synthesized a co-precipitation method for wastewater treatment. The obtained results indicated that FeO nanoparticles exhibited a spherical-shaped morphology, with an average diameter of around 20 nm, and decorated the surface of GO and CNTs. The adsorption data fitted well with the Langmuir isothermal model, exhibiting a coefficient of > 0.

Preparation of chitosan-modified Moringa A liposomes and its protective effect on acute alcoholic liver injury.

Moringa A (MA), the hepatoprotective components of Lam. seeds, are metabolized and eliminated quickly in the body. In this study, cholesterol-modified chitosan (CH-CS) was used as a polymer carrier to prepare chitosan-modified MA liposomes (MA-CLs) in order to slow down the release of MA, prolong its circulation time, and improve the oral bioavailability of MA in comparison with common MA liposomes (MA-Ls).

Porosity dependence of mechanical properties of titanium nanofoams.

Context: This study employs molecular dynamics (MD) simulations to investigate the mechanical properties and deformation mechanisms of titanium (Ti) nanofoam under uniaxial tensile loading. The effects of porosity (ranging from 20 to 50%), strain rate (from 5 × 10⁸ to 5 × 10⁹ s⁻), and temperature (from 300 to 900 K) on the tensile response are systematically examined. The results reveal that increasing porosity significantly reduces the ultimate tensile strength (UTS) and elastic modulus, while intensifying localized shear strain and stress concentration.

Pumpkin Seeds as a Natural Remedy for Anemia: Nutritional Insights and Therapeutic Potential.

Anemia is a widespread global health concern characterized by reduced hemoglobin levels and diminished oxygen-carrying capacity of the blood. According to the World Health Organization, anemia affects 40% of children aged 6 to 59 months, 37% of pregnant women, and 30% of women aged 15 to 49 years globally. The condition is primarily linked to iron deficiency, particularly in low- and middle-income countries, although other factors such as vitamin B12 insufficiency, parasitic infections, chronic diseases, and genetic disorders also contribute.

Humidity-Resistant Piezoelectric Nanogenerator in a Self-Powered Smart Glove for Real-Time Motion Detection and Morse Code Transmission for Remote Workers.

Wearable flexible sensors have gained significant attention for their applications in bioelectronics, human-machine interaction, motion monitoring, and self-powered energy harvesting─especially in scenarios requiring real-time feedback and autonomy. In hazardous or noisy environments, such as in industrial, military, or medical contexts, communication can be severely restricted. To address this, we developed a smart glove embedded with a flexible piezoelectric nanogenerator (FPENG) for real-time, self-powered Morse code transmission via finger movements.