Evaluation of Reflectivities of RPE, ELM, EZ, and Their Relationship With Subretinal Fluid Properties in Central Serous Chorioretinopathy.

Purpose: The purpose of this study was to assess the reflectivity of the outer retinal layers (ORLs) in patients with central serous chorioretinopathy (CSCR) and to examine the relationship between the dimensions of the subretinal fluid (SRF) and ORL.

Methods: This retrospective, cross-sectional study included 33 eyes of 33 patients with CSCR and 33 age- and gender-matched controls. Unnormalized and relative reflectivities for the retinal pigment epithelium (RPE), the external limiting membrane (ELM), and the ellipsoid zone (EZ), as well as SRF height, base width, and area, were measured on optical coherence tomography images.

Effect of Anesthesia Type on Airway Assessment Tests in Cesarean Delivery Operations: A Prospective Comparative Study.

BACKGROUND Pregnancy-related anatomical and physiological changes, such as mucosal edema and increased oxygen demand, heighten risk of difficult airway, especially under general anesthesia. This study compared effects of spinal and general anesthesia on postoperative airway assessment tests in cesarean deliveries. We hypothesized upper airway changes can occur depending on anesthesia technique.

Comparison of hematoma block and dexmedetomidine for reduction of distal radius fractures in the emergency department: a prospective randomized controlled study.

Background: This study aimed to compare the effects of hematoma block (HB) and dexmedetomidine administration on pain control, reduction quality, and physician satisfaction during the reduction of distal radius fractures (DRFs) in the emergency department (ED).

Methods: A total of 60 patients presenting to the ED with DRFs were enrolled. Patients were randomly assigned to two groups: one received HB, while the other underwent conscious sedation with dexmedetomidine.

Quantitative Structure-activity Relationship-based Neural Network Model in Screening Potential Inhibitors from Brown Algae against RelA in Oral Squamous Cell Carcinoma.

Introduction And Aim: Oral squamous cell carcinomas (OSCCs) are one of the most frequently diagnosed head and neck cancers with a poor prognosis despite the advancements in diagnostic techniques and treatment strategies. The progression of OSCC is driven by several molecular mechanisms, among them the overexpression of transcription factor RelA, which plays a crucial role by correlating with the clinicopathological characteristics.

Methods: This systematic investigation focused on identifying the top 25 crucial molecular descriptors to predict the RelA inhibitor through the quantitative structure-activity relationship (QSAR)-based artificial neural network model.

High Nasal Septal Deviation and Anatomical Variations in Esthetic Rhinoplasty Patients.

This retrospective study aims to evaluate paranasal computed tomography (CT) scans that were previously obtained as part of routine preoperative assessment in patients who underwent rhinoplasty for aesthetic purposes, focusing on the prevalence of sinonasal anatomic variations and high septal deviations in cases without nasal axis deformity. The study included 274 patients who underwent rhinoplasty for aesthetic reasons. Preoperative CT images of the patients were evaluated in axial slices with a thickness of 0.

Impact of transcatheter aortic valve implantation on retinal hemodynamics: a Doppler imaging study.

Objectives: After transcatheter aortic valve implantation (TAVI), various hemodynamic alterations occur due to increased cardiac output, which may influence retinal blood flow. This study aimed to evaluate the impact of TAVI on retinal artery dynamics by measuring Doppler parameters before and after the procedure.

Methods: In this prospective, single-centre study, patients scheduled for TAVI were evaluated using retinal Doppler within one week before TAVI, on the first postoperative day, and at one month post-procedure.

Case Report: Cytopathological Diagnosis of Extracranial Anaplastic Meningioma Using Fine-Needle Aspiration.

This case report presents the cytological characteristics of an extracranial anaplastic meningioma-an exceptionally rare entity rarely sampled via fine-needle aspiration. We aim to highlight specific cytomorphological features that may aid in the preoperative identification of the anaplastic subtype.

Hypothermic Oxygenated Perfusion Versus Static Cold Storage in Transplantation of Extended Criteria Liver Grafts: A Systematic Review and Meta-Analysis.

Background: The use of extended criteria donor livers (ECD) is becoming more routine in many transplant centers. These organs have higher risks for complications; however, hypothermic-oxygenated perfusion (HOPE) was found to improve outcomes, including graft survival. We aim to assess the effect of HOPE on different types of ECD liver grafts.

Hashimoto's thyroiditis in children and adolescents: analysis of long-term course.

Objectives: This study retrospectively evaluated long-term clinical and biochemical findings in children and adolescents diagnosed with Hashimoto thyroiditis (HT).

Methods: A total of 233 patients aged 2-18 years, diagnosed with HT and followed for at least three years, were included. Patients were classified into five subgroups based on thyroid stimulating hormone (TSH) and free thyroxine (fT4) levels at diagnosis.

The Use of Serum Scoring Systems in Predicting Liver Fibrosis Caused by Chronic Hepatitis B: A Retrospective Case-Control Study.

: Early diagnosis and monitoring of liver fibrosis in chronic hepatitis B are crucial for effective disease management and prognosis. Traditionally, percutaneous liver biopsy has been regarded as the gold standard for assessing the degree of fibrosis histopathologically. However, this method has several drawbacks.

Comparison of the Effectiveness and Complications of PAIR, Open Surgery, and Laparoscopic Surgery in the Treatment of Liver Hydatid Cysts.

: The aim of this study was to compare percutaneous aspiration injection reaspiration (PAIR), open surgery (OS), and laparoscopic surgery (LS) in the treatment of liver hydatid cysts in terms of effectiveness, complications, and recurrence rates. : This retrospective cross-sectional study included 383 patients who were treated with a diagnosis of liver hydatid cyst at Harran University Faculty of Medicine between May 2014 and May 2024. Patients were divided into three groups based on the treatment method: PAIR, OS, and LS.

The Construct and Predictive Validity of the Japanese Version of the Intensive Care Unit Mobility Scale.

: The increasing emphasis on early mobilization in intensive care units (ICUs) has underscored the need for quick, simple, and reliable tools to assess patients' mobilization levels. The ICU Mobility Scale (IMS) was developed to address this need and has been translated into a Japanese version. This study aimed to evaluate the construct and predictive validity of the Japanese version of the IMS in critically ill patients.

Epidemiology of Kidney Disease in People Living with HIV in Türkiye; Comorbidities and Drug Toxicities are Emerging Problems.

Introduction/objective: To reveal the epidemiology of kidney disease (KD) in people living with HIV (PWLH) and to report the antiretroviral treatment (ART) management in case of kidney disease.

Methods: This multicenter, retrospective observational study identified KD under four categories: acute kidney disease (AKD), chronic kidney disease (CKD), accelerated decline of glomerular filtration rate (GFR > 60 mL/min), and asymptomatic kidney disease indicated by markers of kidney damage. Clinical characteristics and etiological causes of KD in patients were evaluated.

ChatGPT-4.0 or DeepSeek-V3? Comparative analysis of answers to the most frequently asked questions by total knee replacement candidate patients.

Background: Total knee arthroplasty (TKA) is a surgical intervention that significantly improves patients' quality of life, but the preoperative process can cause uncertainty, anxiety, and a lack of information. In recent years, artificial intelligence (AI)-powered chatbots and large language models have begun to play important roles in patient information processes in the healthcare field. In this study, the answers given by chat generative pretrained transformer (ChatGPT)-4.

Geospatial Insights into Access to Kidney Transplantation in Underserved Hispanic Communities.

Introduction: The rising Hispanic population in the U.S. is at significant end-stage kidney disease (ESKD) risk.

Prevalance and risk factors of congenital malaria in Osogbo, Southwestern Nigeria.

Background: Congenital malaria, defined as the presence of malaria parasites in the peripheral smear of newborns within the first seven days of life, remains an underexplored aspect of malaria epidemiology in endemic regions like Nigeria. This study investigated the prevalence and associated risk factors of congenital malaria at the State Specialist Hospital (SSH), Osogbo, Southwestern Nigeria.

Method: This cross-sectional study collected peripheral and cord blood samples from 77 newborns within the first 24 hours of delivery.

Diagnostic advancements in early detection of diabetic neuropathy: comparative analysis of medial and lateral plantar nerve degeneration.

Diabetic neuropathy (DN) is a widespread complication of diabetes, affecting nearly 50% of individuals with the condition. It commonly begins with the gradual loss of sensation in the lower extremities, particularly in the feet. If left undetected and untreated, this loss of sensation can lead to serious consequences, such as foot ulcers and eventual amputations.

Bowel Preparation Quality in Patients Using Glucagon-Like Peptide-1 Agonists: A Systematic Review and Meta-Analysis.

Background And Aims: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are now the mainstay treatment for many chronic conditions including diabetes mellitus, obesity, heart failure and chronic kidney disease. GLP-1 RAs may affect bowel preparation for a colonoscopy by modifying intestinal motility and gastric emptying. We conducted a systematic review and meta-analysis to investigate the impact of GLP-1 RA use on bowel preparation quality, measured by the Boston Bowel Preparation Scale (BBPS), and the frequency of inadequate preparation events.

Identification of salivary inflammatory non coding RNA biomarkers for coronary artery disease through epicardial adipose tissue gene network analysis.

Background And Aim: Epicardial adipose tissue (EAT), due to its proximity to the myocardium, contributes inflammatory profile in CAD onset and progression. Emerging evidence highlights the role of EAT-derived non-coding RNAs in modulating disease pathways. However, identifying EAT-specific biomarkers remains challenging for routine diagnosis.

Wide-awake local anaesthesia no tourniquet-assisted subcutaneous anterior ulnar nerve transposition in cubital tunnel syndrome: A retrospective evaluation.

Although several studies have demonstrated the successful use of wide-awake local anesthesia no tourniquet (WALANT) technique in cubital tunnel decompression, no prior study has investigated its use in anterior ulnar nerve transposition. This study aimed to retrospectively evaluate the outcomes of patients who underwent ulnar nerve decompression and subcutaneous anterior transposition using WALANT. A total of 41 surgeries were performed on 40 patients between August 2012 and March 2024 by a single surgeon.