tACS-combined motor training for the rehabilitation of the upper limb in children and adolescents with cerebral palsy: A randomized, sham-controlled trial protocol.

Background: Children with cerebral palsy (CP) commonly face gross motor function impairments and manual dexterity deficits, significantly affecting their activity level and independence and, ultimately, quality of life. Rehabilitation often targets improving manual dexterity and activity levels, but standard therapies have limited efficacy. Hence, exploring novel methods to enhance upper limb functionality is crucial.

Increased GM-WM in a prefrontal network and decreased GM in the insula and the precuneus are associated with reappraisal usage and reduced perceived stress: A data fusion approach.

Emotion regulation plays a crucial role in mental health, and difficulties in regulating emotions can contribute to psychological disorders. While reappraisal and suppression are well-studied strategies, the joint contributions of gray matter (GM) and white matter (WM) to these strategies remain unclear due to methodological limitations in previous studies. To address this, we applied a data fusion approach using Parallel Independent Component Analysis (Parallel ICA) to GM and WM MRI images from 165 individuals.

A dedicated deep learning workflow for automatic Fasciola hepatica and Calicophoron daubneyi egg detection using the Kubic FLOTAC microscope.

Fasciola hepatica and Calicophoron daubneyi are trematodes with significant health and economic impacts on ruminant livestock farms. An effective and reliable diagnosis is essential to control their spread. To improve copromicroscopic diagnosis, the Kubic FLOTAC Microscope (KFM), a portable digital microscope, was designed for both laboratory and field use.

Barriers Related to the Identification and Satisfaction of the Sexual Needs of Nursing Homes' Residents: A Narrative Review.

Background: Sexuality is a central aspect of being human, even if people experience it in different ways in various stages of life. Sexuality in older people may be expressed, as well as affection, companionship, touch, and physical contact. However, older peoples' sexual needs are not properly considered by themselves, caregivers, or healthcare professionals.

Neuroanatomical and Functional Correlates in Bipolar Disorder (BD): A Narrative Review.

The incidence of mood disorders in the general population is quite high. Among the most common is bipolar disorder (BD), often associated with severe mood disorders, psychotic changes (e.g.

Timmy's Trip to Planet Earth: The Long-Term Effects of a Social and Emotional Education Program for Preschool Children.

Background/objectives: Social and Emotional Education (SEE) interventions during early childhood have shown considerable promise in enhancing children's emotion understanding, social competence, and behavioural adjustments. However, few studies have examined their long-term impact, especially across the preschool-to-primary school transition. This study evaluated the effectiveness of a manualized SEE program, Timmy's Trip to Planet Earth, in promoting emotional, behavioural, and social functioning over time.

Connected by Boredom: A Systematic Review of the Role of Trait Boredom in Problematic Technology Use.

In an increasingly pervasive digital environment, trait boredom has been identified as a key psychological factor in the onset and maintenance of problematic digital technology use. This systematic review aims to investigate the role of trait boredom in digital behavioral addictions, including problematic smartphone use, Internet and social media overuse, and gaming addiction, through theoretical models such as the I-PACE model and the Compensatory Internet Use Theory (CIUT). A systematic literature search was conducted across multiple scientific databases (PsycINFO, Web of Science, PubMed, and Scopus), yielding a total of 4603 records.

The System of Corrective Interventions in the Sex Offender Population and the Proposed "Trident Statal Program" (TSP) in the Field of Italian Sex Crimes.

The issue of effective treatments for individuals with a history of sexual offending has legal, social, economic, political, and clinical impacts. Studies conducted on the topic of evaluating treatment outcomes for sex offenders have examined both biological and psychological interventions. The etiology of the phenomenon appears to be multifactorial, as the sexual harasser learns from the social and family context the norms that will constitute our framework of rules, in addition to the characteristics of temperament, character, and personality.

Effect of Technological Process and Temperature on Phospholipids in Buffalo Milk, Whey and Buttermilk.

Phospholipids (PLs) are a group of biomolecules found in the milk fat globule membranes (MFGMs). Recently, MFGM phospholipids have attracted increasing amounts of attention due to their unique composition, stability, and potential health benefits, including protective effects against Alzheimer's disease, hypercholesterolemia, and certain types of cancer. Although buffalo milk is the second most commonly produced milk and has high nutritional value, few studies have focused on the properties of buffalo MFGM.

A fronto-insular network underlies individual variations in anger expression and control.

Anger can be deconstructed into distinct components: a tendency to outwardlyexpress it (anger-out) and the capability to manage it (anger control). Theseaspects exhibit individual differences that vary across a continuum. Notably,the capacity to express and control anger is of great importance to modulate ourreactions in interpersonal situations.

CALS and ACB Scales are Associated with Physical and Cognitive Impairment and Predict Mortality in Nursing Home Residents.

Background And Objective: Anticholinergic medications are known to affect the prognosis of older nursing home residents. Various anticholinergic scales were developed to measure the cumulative anticholinergic burden; among them, the CRIDECO Anticholinergic Load Scale (CALS) has recently emerged as a new tool to identify patients with cognitive impairment due to anticholinergic burden. This study aimed to externally validate the CALS and to evaluate the association of CALS and the anticholinergic cognitive burden (ACB) scales with baseline cognitive and functional impairment, as well as with 3-year mortality rates.

Electrically controlled heat transport in graphite films via reversible ionic liquid intercalation.

The ability to control heat transport with electrical signals has been an outstanding challenge due to the lack of efficient electrothermal materials. Previous attempts have mainly concentrated on low-thermal conductivity materials and encountered various problems such as narrow dynamic range and modest on/off ratios. Here, using high-thermal conductivity graphite films, we demonstrate an electrothermal switch enabling electrically tunable heat flow at the device level.

Comparison between and used in sequential wine fermentations with .

Introduction: The interest toward the use of non- yeasts in the winemaking process has been increasing because it has been demonstrated that they can contribute positively to the quality of wines; however, there is a gap in the literature on holistic approaches showing the effective contribution of non- yeasts in sequential fermentations.

Methods And Results: Two commercial strains of (Mp) and (Td) were used in sequential fermentations with (Sc). The fermentations were monitored by evaluating cell viable counts, ethanol, glycerol, acids, amino acids, phenols, total antioxidant activity, total polysaccharides, and volatile organic compounds (VOCs).

A novel repellent bioassay to evaluate the effect of wood vinegar against louse .

The water buffalo farm with intensive breeding techniques promotes the spread of lice (), leading to a reduction in meat and milk productions. Current control measures include the use of chemicals, which in the long-term lead to the development of resistance. Given the lack of alternative solutions, the aim of this study was to evaluate the repellent effect of a low impact by-product, the wood vinegar (WV), against using a new bioassay test.

The effect of compositional fluctuations in a liquid Fe-O alloy on the nucleation of Earth's inner core.

The Earth's solid inner core plays a fundamental role in determining the past and present properties and dynamics of the Earth's deep interior. Inner core growth powers the geodynamo, producing the protective global magnetic field, and provides a record of core evolution spanning geological timescales. However, the origins of the inner core remain enigmatic.

Effects of EEG-guided transcranial alternating current stimulation (tACS) of the cerebellum on motor behavior and electrophysiological activity.

The cerebellum plays a key role in motor control, yet its oscillatory dynamics remain poorly understood due to anatomical and methodological constraints. Transcranial alternating current stimulation (tACS) has emerged as a promising tool to modulate cerebellar activity, particularly when tailored to individual neural oscillations. This study examined the effects of EEG-guided gamma-frequency cerebellar tACS-matched to each participant's individual gamma frequency (IGF)-on motor performance and neurophysiological markers in healthy adults.

Covarying gray and white matter networks characterize schizophrenia and bipolar disorders on a continuum: A data fusion machine learning approach and a brain network analysis.

Schizophrenia (SZ) and Bipolar disorder (BD) share genetic and cerebral abnormalities, supporting an expanded continuum hypothesis. In this paper, we aim to better characterize differences and commonalities of gray and white matter features between SZ and BD to clarify how they align or diverge on this continuum. We transposed independent vector analysis (tIVA), a data fusion technique, to the gray and white matter images of 128 individuals diagnosed with SZ, 128 with BD and 127 healthy controls (CTRL), matched for gender, age and IQ.

Limitations in Determining Oxidation States in Condensed Matter at the Subnanometric Scale.

The oxidation state is a fundamental chemical concept commonly employed to rationalize, classify, and predict the chemical reactivity of a variety of compounds. Understanding and defining the elemental oxidation state of solid materials at the atomic level becomes increasingly complex as their physical dimensions are reduced from tens of nanometers─where properties are still dominated by bulk or outer atomic crystal plane characteristics, to the subnanometric limit. In this work, we highlight the significant limitations in determining even a basic quantity, such as the oxidation state, when oxidized low-nuclearity mass-selected clusters are investigated by means of X-ray photoelectron spectroscopy (XPS), widely recognized as the elective approach to resolve different oxidations states.

Psychological distress and myocardial infarction (MI): A cross-sectional and longitudinal UK population-based study.

Objective: The objective of the present research is to establish the cross-sectional and longitudinal associations between dimensions of psychological distress (i.e., social dysfunction and anhedonia, depression and anxiety, and loss of confidence) and the risk of clinically diagnosed myocardial infarction (MI).

Genetic variability in ADAM17/TACE is associated with sporadic Alzheimer's disease risk, neuropsychiatric symptoms and cognitive performance on the Rey Auditory Verbal Learning and Clock Drawing Tests.

Recent studies have highlighted the significant role of ADAM17/TACE (encoded by ADAM17/TACE) in the pathogenesis of Alzheimer's disease (AD). Yet, the relationship between ADAM17/TACE gene polymorphisms and AD was less studied. This study aims to analyse the relationship of ADAM17/TACE gene polymorphism with the risk, age of onset, neuropsychiatric manifestations, cognitive impairment, and medial temporal lobe atrophy in sporadic AD (sAD).

Dropout in Psychotherapy for Personality Disorders: A Systematic Review of Predictors.

Introduction: Dropout in psychotherapy for personality disorders is a major challenge, affecting treatment efficacy and mental health care delivery. Influenced by patient characteristics, therapist factors and treatment dynamics, dropout remains prevalent. This systematic review identifies predictors of psychotherapy dropout in individuals with personality disorders to inform strategies that enhance treatment engagement.

Psychoeducational Program Increases Telomerase Activity in Bipolar Disorder: A Gender-Based Randomized Controlled Trial.

Aims: This randomized controlled trial evaluated the efficacy of a psychoeducational program in enhancing telomerase activity (TA) among patients with bipolar disorder (BD), with a specific focus on gender differences.

Methods: A total of 62 participants were assigned to either the psychoeducation (PE) group or the control (CTR) group, with TA measured both before and after the intervention.

Results: Results demonstrated a significant increase in TA in the PE group compared to the controls at the conclusion of the study.

Deepfake Media Forensics: Status and Future Challenges.

The rise of AI-generated synthetic media, or deepfakes, has introduced unprecedented opportunities and challenges across various fields, including entertainment, cybersecurity, and digital communication. Using advanced frameworks such as Generative Adversarial Networks (GANs) and Diffusion Models (DMs), deepfakes are capable of producing highly realistic yet fabricated content, while these advancements enable creative and innovative applications, they also pose severe ethical, social, and security risks due to their potential misuse. The proliferation of deepfakes has triggered phenomena like "Impostor Bias", a growing skepticism toward the authenticity of multimedia content, further complicating trust in digital interactions.