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Article Abstract
Aims: This randomized controlled trial evaluated the efficacy of a psychoeducational program in enhancing telomerase activity (TA) among patients with bipolar disorder (BD), with a specific focus on gender differences.
Methods: A total of 62 participants were assigned to either the psychoeducation (PE) group or the control (CTR) group, with TA measured both before and after the intervention.
Results: Results demonstrated a significant increase in TA in the PE group compared to the controls at the conclusion of the study. Notably, gender-specific analyses revealed that female participants showed significant increases in both TA and delta TA (Δ), with Δ PE = 0.586 ± 0.273 and Δ CTR = -0.251 ± 0.177. In contrast, male participants exhibited significant changes only in Δ, with Δ PE = 0.257 ± 0.138 and Δ CTR = -0.144 ± 0.1194.
Conclusion: These findings suggest that psychoeducational interventions have differential gender-specific effects, underscoring the importance of personalized approaches in the treatment of BD.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982523 | PMC |
| http://dx.doi.org/10.1111/cns.70292 | DOI Listing |
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