Rare Metastases to Liver and Spleen form a Seldom Case of Facial Angiosarcoma Demonstrated on Staging FDG PET-CT.

Angiosarcoma is a rare type of soft-tissue sarcoma, constituting only 1% out of all soft-tissue sarcomas pathologically originating from lymphatic or vascular endothelial cells. Angiosarcomas are reported to be very aggressive with a high incidence of metastases to different sites; therefore, it is very important to determine disease extension and detect local recurrence and/or distant metastases for appropriate management. We report a case of a 55-year-old Indian male who presented with soft-tissue thickening of the left cheek for which biopsy revealed angiosarcoma and was referred for fludeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) to assess the extent of disease highlighting the potential role of FDG PET/CT in rare malignancies like angiosarcomas.

Exploring the Utility of FDG PET-CT in Metastatic Recurrent Extra Skeletal Renal Osteosarcoma.

Metastatic renal osteosarcoma is a rare entity. We report a case of a 52-year-old male postright nephrectomy status presented to us with metastatic renal osteosarcoma. 18-fluorine- fluorodeoxyglucose (F-FDG) avid lesions were seen in the right renal bed with extension to adjacent hepatic parenchyma.

A Comparative Evaluation of the Accuracy of Invasive Point-of-care Hemoglobin Devices.

Aims: The aim of the study was to evaluate the accuracy of two devices that measure hemoglobin (Hb) from blood samples taken from small capillary tubes (HemoCue® Hb 301 System) and another from whole blood taken from veins or arteries (Horiba H550) with a laboratory reference analyzer (Beckman Coulter DxH 520).

Subjects And Methods: A cross-sectional study was conducted, in which capillary and venous blood samples were taken from 529 individuals across outpatient and inpatient wards of both genders, with an age range from 7 to 83 years. The accuracy and agreement were statistically evaluated using Lin's concordance correlation coefficient.

Global anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study.

Introduction: Restoration of surgical capacity is essential to post-COVID-19 recovery. This study explored the use and safety of anaesthesia options for inguinal hernia surgery, a common tracer condition, to describe current global practice and highlight opportunities to build the capacity of health systems.

Methods: This is a secondary analysis of an international prospective cohort study of consecutive patients who underwent elective inguinal hernia surgery.

Circulating SLC17A5 as a Diagnostic Biomarker of Early Endothelial Dysfunction in Young Dyslipidemic Individuals.

Diagnostic potential of sialin in identifying endothelial dysfunction is explored. 50 CAD patients, 50 young (20-35 years) dyslipidemic individuals (DLP), and 50 healthy controls (HC) were included in the study. HUVECs were stimulated with either TNFα or AT-2.

A critical review of high-frequency activity for functional mapping in SEEG.

Mapping functional brain networks is a critical component of stereo-electroencephalography (SEEG) evaluations. Although direct cortical stimulation (DCS) is the clinical gold standard, it has important limitations-particularly in mapping distributed, complex functions such as language and memory, where deficits may still occur despite preservation of DCS-positive sites, impacting quality of life. More broadly, there is increasing emphasis on preserving cognitive function in epilepsy surgery.

The Indo-European Cognate Relationships dataset.

The Indo-European Cognate Relationships (IE-CoR) dataset is an open-access relational dataset showing how related, inherited words ('cognates') pattern across 160 languages of the Indo-European family. IE-CoR is intended as a benchmark dataset for computational research into the evolution of the Indo-European languages. It is structured around 170 reference meanings in core lexicon, and contains 25731 lexeme entries, analysed into 4981 cognate sets.

Caregiver-Mediated Early Support Program Delivered Online Versus Care-as-Usual for Infants at Elevated Familial Likelihood for Autism: A Parallel, Assessor Masked, Feasibility Randomized Controlled Trial in India.

LiL' STEPS (Language development & Intervention Lab's SupporTing Early social-communication and language by Promoting caregiver Sensitive responsiveness) is a novel, manualized, caregiver-mediated early support program developed in India and delivered online for infants at elevated familial likelihood for autism. The program has been found to be feasible and acceptable. The preliminary efficacy of the LiL' STEPS program, which remains to be evaluated, was assessed in this study using a feasibility randomized controlled trial design.

In-situ hydrogen bonding driven green extraction of five Sudan dyes from tomato ketchup using thymol followed by UHPLC-PDA analysis.

We explored the potential of thymol and menthol, which are natural hydrophobic compounds containing hydrogen-bond-donor and -acceptor group, as an extractant and developed an extraction method for the simultaneous determination of five Sudan dyes in tomato ketchup. To maximize extraction efficiency, we optimized key factors that affect the extraction process. The samples were then analysed using UHPLC-PDA.

Antioxidant, Antidiabetic Study and Wastewater Remediation by Selenium Nanoparticles of Hesperidin.

Nanotechnology has opened several applications in engineering, waste management and biomedical science. Metal nanoparticles of inorganic metals have unique electrical, magnetic, optical and physicochemical properties, making them superior to bulk metals. Selenium nanoparticles are less toxic than inorganic selenium, which has a narrow therapeutic index and high toxicity.

PRACT-India: Practical Recommendations on Acne Care and Medical Treatment in India-A Modified Delphi Consensus.

Acne vulgaris is a prevalent dermatological condition, yet clear, region-specific management guidelines, particularly for India's diverse population, remain limited. Effective acne management extends beyond pharmacologic therapy, emphasizing proper skincare, patient education, and adherence strategies. This consensus aims to provide tailored, evidence-based recommendations for optimizing acne treatment in the Indian context.

Clinical study to evaluate the efficacy and safety of an herbal toothpaste in reducing gingivitis in a diabetic population.

Purpose: To assess the efficacy and safety of Glister multi-action toothpaste Herbals (GHT) on gingivitis in diabetic subjects.

Methods: A total of 72 diabetic subjects were enrolled and 61 subjects completed the open label single arm clinical study for a period of 30 days. Subjects were evaluated on Day 10 (visit 3), Day 20 (visit 4), and Day 30 (visit 5) for reduction in gingivitis, plaque, gingival bleeding, pocket depth, S.

Water-In-Glass: A Self-Supporting Inorganic Aqueous Electrolyte.

Aqueous rechargeable sodium-ion batteries (ARNIBs) are emerging as cost-effective and safe candidates for large-scale energy storage applications. However, their advancement has been constrained by the narrow electrochemical stability window (ESW) of conventional aqueous electrolytes (1.23 V).

Neuroendocrine Effects of Hyperprolactinemia: Focus on Dopamine and Serotonin Systems.

Hyperprolactinemia is characterized by unusually high levels of prolactin, a hormone primarily known for regulating reproductive functions. However, studies have shown that prolactin has also a significant impact on various neurotransmitter systems in the brain. This review examined the intricate relationship between hyperprolactinemia and neurotransmission, with a particular emphasis on the dopaminergic and serotonergic systems.

Bacterial diversity in the freshwater sponges of Sundarban and their potential role in biomonitoring toxic element pollution.

Sponges serve as the natural cleaner in diverse aquatic ecosystems, harboring diverse microbial communities and forming a highly specialized holobiont. The present study provides the first insights into the bacterial communities associated with freshwater sponges of Sundarban, highlighting their distinct microbial community composition compared to the surrounding water using 16S rRNA gene-based metataxonomic analyses. The analysis encompassing six sponge species collected from Sagar Island and Ghoramara revealed distinct variations in microbial abundance and diversity compared to their ambient water, suggesting selective bacterial associations with the sponges.

A Study on the Quality of Life and Economic Burden Among People Living With HIV/AIDS and Attending a Tertiary Care Hospital in Jharkhand, India.

Background AIDS, a potentially life-threatening disease caused by a retrovirus known as human immunodeficiency virus (HIV), has evolved from a mysterious illness to a global pandemic, affecting tens of millions of people. HIV/AIDS poses an increasing threat to the health of the population and causes further socioeconomic loss for people, communities and governments in many countries and drastically affects the quality and standard of life. Very few studies have used the World Health Organization Quality of Life HIV Brief Scale (WHOQOL-HIV BREF) instrument in people living with HIV and AIDS (PLWHA).

Key frame extraction based abnormal vehicle identification technique using statistical distribution analysis.

In recent days, due to potential growth of vehicle usage, the researchers have to concentrate on abnormal vehicle identification areas to provide solutions to avoid accidents. Though many vehicle identification works have been done by applying machine and deep learning approaches, still there is some problem with handling repetition frames and identifying the abnormal vehicles among vehicles in a camera. To overcome these challenges, this paper introduces KFEAVI (Key Frame Extraction based Abnormal Vehicle Identification) technique that uses statistical feature extraction technique and constrained angular second moment technique.

Profile of central line-associated bloodstream infections in adult, paediatric, and neonatal intensive care units of hospitals participating in a health-care-associated infection surveillance network in India: a 7-year multicentric study.

Background: Central line-associated bloodstream infections (CLABSIs) are preventable health-care-associated infections (HAIs) that cause considerable morbidity and mortality. Understanding the epidemiology of CLABSIs through large, quality-assured, hospital-based datasets could help to enable development of preventive protocols suited to specific health-care systems. We aimed to describe the profile of CLABSIs in intensive care units (ICUs) at tertiary care centres in India.

SiC ultra -thin films for high-performance quantum spacecraft applications fabricated via nanosecond pulsed laser deposition and doping.

This research investigates the deposition, characterization of SiC ultra-thin films deposited by nanosecond pulsed Nd3 ⁺ laser deposition technique and laser assisted doping. These SiC films possess better qualities in terms of surface roughness varying from 2-5 nm. Using an atom probe tomography (APT) and a transmission electron microscope (TEM), key elemental maps showed desirable concentrations of Si of ~50 at.

Assessing Cravings Among Individuals with Alcohol Dependence Syndrome Prescribed with Anti-craving Medication: A Prospective Observational Study.

Background: Alcohol Dependence Syndrome (ADS) is a prevalent condition marked by difficulty controlling alcohol use, with significant global health impacts. Despite the effectiveness of anti-craving medications like Naltrexone, Acamprosate, Baclofen, Ondansetron, and Topiramate, these medications remain underutilized by healthcare providers. This study aims to assess the relationship between craving and relapse rates among individuals prescribed anti-craving medications and to explore the correlation between medication dosage and craving severity.

Therapeutic Potentials of Jamun () and Its Integration Into Modern Food Technologies: A Review.

In a world where consumer preferences continue to pivot toward healthier and eco-conscious choices, jamun () emerges as an underutilized resource with untapped potential. Despite the abundance of phytochemicals, the fruit also encounters postharvest losses, pointing toward extensive processing and additional research for sustainable utilization of food. The review brings together an understanding of existing knowledge on the therapeutic potentials of jamun and its integration into modern food technologies, providing valuable insights for food researchers and healthcare professionals aiming to leverage the health-promoting properties of this remarkable fruit to enhance human well-being.

FDG PET/CT Imaging in Mucormycosis: A Novel Approach for Early Detection and Disease Monitoring.

Background: To evaluate the role of FDG PET/CT in diagnosing and monitoring rhinocerebral mucormycosis (RCM) and its added value over conventional imaging.

Patients And Methods: We conducted a prospective observational study of 47 adults with biopsy-confirmed rhinocerebral mucormycosis between July 2022 and September 2024. All patients underwent FDG PET/CT, and findings were compared with MRI/CT and correlated with microbiological or histopathologic results.