Preclinical evaluation of [La]La-FAP-2286 as a novel theranostic agent for tumors expressing fibroblast activation protein.

In this study, a novel theranostic radiopharmaceutical, [La]La-FAP-2286, for targeting Fibroblast Activation Protein (FAP)-positive tumors. The theranostic pair of La (half-life: 4.59 h, 42.

Energy and cost analysis of bottom waste cooking oil (B-WCO) based solid alcohol biofuel and supernatant waste cooking oil (S-WCO) based biodiesel.

Waste cooking oil (WCO) represents one of the most available renewable energy sources to produce solid alcohol biofuel (SABF) and biodiesel. The objective of this work is to conduct energy and cost balances for biodiesel and SABF generation from supernatant waste cooking oil (S-WCO) and bottom waste cooking oil (B-WCO) derived from catering facilities in Iran, respectively. The total energy input/output for SABF and biodiesel, respectively, were 31.

Advanced computational approaches for predicting sunflower yield: Insights from ANN, ANFIS, and GEP in normal and salinity stress environments.

Prediction of crop yield is essential for decision-makers to ensure food security and provides valuable information to farmers about factors affecting high yields. This research aimed to predict sunflower grain yield under normal and salinity stress conditions using three modeling techniques: artificial neural networks (ANN), adaptive neuro-fuzzy inference system (ANFIS), and gene expression programming (GEP). A pot experiment was conducted with 96 inbred sunflower lines (generation six) derived from crossing two parent lines, over a single growing season.

Elucidating the synergistic effects of aeration and non-thermal plasma on the degradation pathways of specific pollutants in wastewater.

Organic pollutants originating from industrial discharges pose significant threats to human health and ecological balance. Conventional pretreatment methods face challenges due to high costs, limited efficiency, and the generation of residual sludge. Non-thermal plasma (NTP) technology, a promising advanced oxidation process, has attracted substantial research interest for its potential to rapidly and effectively treat industrial wastewater.

Grass pea dual purpose dry matter and seed yields in rainfed conditions across diverse environments.

Grass pea (Lathyrus sativus L.) stands out as an excellent choice for sustainable agriculture, thanks to its favorable agronomic characteristics, including a robust root system that penetrates deeply into the soil and its resilience against various biotic and abiotic stressors. In this study, dry-matter yield and seed yield of 16 grass pea genotypes were evaluated in rain-fed conditions at "Gachsaran", "Mehran", "Kuhdasht", and "Shirvan-Chardavol" locations in Iran for three consecutive years.

Effect of different crystalline directions on the mechanical properties and processing maps of Zr-Nb alloy for orthopedic applications.

In the current study, the effect of direction on the hot compression behavior, processing map, and microstructure of Zr-Nb alloy after bidirectional hot forging was studied. Accordingly, the alloy billet was hot-forged and samples at different directions were extracted. Phase changes and microstructure of the samples were characterized.

Dosimetry characteristics of polycarbonate/bismuth oxide nanocomposite for real-time application in the field of gamma-rays.

Background: Polymer-carbon nanostructures have previously been introduced for dosimetry of gamma rays with potential application in radiotherapy. In this research work, bismuth oxide (BiO) nanoparticles were added into the amorphous polycarbonate (PC) matrix to enhance the probability of the photoelectric effect and dosimetry response in parallel.

Materials And Methods: PC/BiO nanocomposites at concentrations of 0, 5, 20, 40, and 50 BiO wt% were fabricated via a solution method.

AutoPVPrimer: A comprehensive AI-Enhanced pipeline for efficient plant virus primer design and assessment.

Plant viruses pose a significant threat to global agriculture and require efficient tools for their timely detection. We present AutoPVPrimer, an innovative pipeline that integrates artificial intelligence (AI) and machine learning to accelerate the development of plant virus primers. The pipeline uses Biopython to automatically retrieve different genomic sequences from the NCBI database to increase the robustness of the subsequent primer design.

Preparation and Biodistribution Assessment of Lu-curcumin as a Possible Therapeutic Agent.

Purpose: Curcumin as a potent anti-inflammatory and cancer-prevention molecule was labeled with n.c.a Lu.

Enhancing diagnostic accuracy in breast cancer: integrating novel machine learning approaches with enhanced image preprocessing for improved mammography analysis.

Purpose: This study explored the use of computer-aided diagnosis (CAD) systems to enhance mammography image quality and identify potentially suspicious areas, because mammography is the primary method for breast cancer screening. The primary aim was to find the best combination of preprocessing algorithms to enable more precise classification and interpretation of mammography images because the selected preprocessing algorithms significantly impact the effectiveness of later classification and segmentation processes.

Material And Methods: The study utilised the mini-MIAS database of mammography images and examined the impact of applying various preprocessing method combinations to differentiate between malignant and benign breast lesions.

Shielding design and heat transfer analysis of the transportation container of a hot batch in the Mo production facility.

In molybdenum-99 (Mo) production facilities via the fission method, appropriate transportation containers must be used to transfer irradiated targets from the irradiation facility to the processing facility, following the requirements for transferring radioactive materials. In the Mo production industrial plan of Iran, the transportation container must be capable of carrying a holster containing nine irradiated low-enriched uranium targets, known as a hot batch. In this article, the proper shielding of two-layer containers based on the gamma spectrum emitted from the radioisotope inventory of a local hot batch, including fission products, activation products, and other radioisotopes produced from their decay chains, was investigated by using Monte Carlo code MCNP6.

Role of gamma irradiation and disaccharide trehalose to induce immune responses in Syrian hamster model against Iranian SARS-CoV-2 virus isolate.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is the causative agent of the emerging zoonotic respiratory disease. One of the most important prerequisites for combating emerging diseases is the development of vaccines within a short period of time. In this study, antigen-irradiated, inactivated SARS-CoV-2 viruses and the disaccharide trehalose were used to enhance immune responses in the Syrian hamster.

Determination of optimal gamma radiation dose for mutation breeding in 'Sabz' fig (Ficus carica L.) cuttings based on radiosensitivity and phenotypic changes.

The dried fig cv. Sabz of Iran, distinguishes out among the several fig cultivars for its unique characteristics and excellent properties. The aims to this study were 1) Carefully monitoring the resulting phenotypic changes in growth patterns, leaf morphology, shoot traits, root characteristics, and other relevant traits after irradiated with different gamma rays; 2) Investigating the LD25, 50, 75 and GR25, 50, 75 values at different gamma radiation doses for chose optimum dose.

[In]In-RM2: a high potential agent for SPECT imaging of GRPR-expressing tumors.

Gastrin-releasing peptide receptors (GRPRs) overexpressed in many cancers are known as promising biomarkers to target tumors such as prostate, breast, and lung cancers. As the early diagnosis of the cancers can serve for better treatment of the patients, [In]In-DOTA-Pip-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ([In]In-RM2) was prepared using an in-house developed Sn/In generator. 0.

Interpret probability density functions and maximum entropy model for zinc removal in PRDC column by analyzing droplet size distribution.

The research discussed in this paper focused on experimental data using a perforated rotating disc column to determine the factors that impact the distribution of drop sizes. A standard test system was utilized, consisting of zinc ions and D2EHPA extractant. When the rotor speed is increased, a majority of droplets display a smaller range of diameters, primarily because of decreased coalescence and increased breakup effects.

Evaluation of cyanex272 in the emulsion liquid membrane system for separation of thorium.

This study describes the use of the emulsion liquid membrane (ELM) technique to recover thorium (Th(IV)) from an aqueous nitrate solution. The components of the ELM were kerosene as a diluent, sorbitan monooleate (span 80) as a surfactant, bis(2,4,4-trimethylpentyl)phosphinic acid (Cyanex 272) as an extractant, and HSO solution as a stripping reagent. Th(IV) was more successfully extracted and separated under the following favorable conditions: Cyanex272 concentration of 0.

Influence of Newborns' Sex on Minor and Trace Element Concentrations in Human Milk During Early Lactation.

This study aimed to investigate the influence of newborns' sex on the concentrations of minor and trace elements in the human milk of lactating mothers during early lactation. The elemental analysis focused on calcium (Ca), potassium (K), sodium (Na), and chlorine (Cl) as minor elements and iodine (I), aluminum (Al), bromine (Br), and rubidium (Rb) as trace elements. Breast milk samples were collected from 75 lactating mothers in Tehran, Iran, during the early feeding stage.

Dose mapping of an irradiation chamber of a gamma cell unit using Fricke gel dosimeters and Monte Carlo simulation.

A gamma cell unit is used for gamma irradiation of small volume samples. Due to the sample volume, there is a dose distribution, which is imperative to be known for appropriate irradiation. In this study, samples of agarose Fricke gel dosimeters were prepared for the dose mapping of the gamma cell unit available in our laboratory.

Bioinformatics deciphers the thebaine biosynthesis pathway in opium poppy: Hub genes, network analysis, and miRNA regulation.

Thebaine, a vital precursor in the codeine and morphine pathway, shows promise in addiction treatment. We conducted a comprehensive study on the thebaine biosynthesis pathway in opium poppy, utilizing bioinformatics tools. The dataset comprising the thirteen genes associated with the thebaine biosynthesis pathway was compiled from an extensive review of published literature and validated using the NCBI BLAST tool.

Improvement of detector shield in PGNAA facility for boron concentration measurement.

A radiation shield consists of borated polyethylene (7 % wt of boron) and lead was used for the HPGe detector in Isfahan MNSR's PGNAA facility in order to remove scattered neutrons and gamma rays, respectively. Therefore, the boron peak in gamma spectroscopy is related to both resources in the sample and in the shield, and it has caused a challenge in determination of boron concentration in the samples. In this research, various methods have been investigated to remove the effect of boron in the shield of the detector.

The potential of TiCT-KHPO and TiCT-chitosan in the efficient removal of cesium from nuclear wastewater.

TiCT is synthesized from TiAlC by two common methods, HF and HF in situ. The synthesis approach is very practical regarding the structure, morphology, space between layers, type and number of surface-active sites and its specific surface. XRD, SEM, EDS, FTIR and BET analyzes were used to investigate the structure, morphology, type and number of surface-active sites.