Radiation-induced single event effects in vertically prolonged drain dual gate Si Ge source TFET.

Context: This study investigates the radiation tolerance of a SiGe source vertical tunnel field effect transistor (VTFET) under heavy ion-induced single event effects (SEEs). Single event effects (SEEs) occur when high-energy particles interact with semiconductor devices, leading to unintended behavior. The effect of high energy ions on the VTFET is examined for various linear energy transfer (LET) values and at multiple ion hit locations.

The puzzle of high lifetime and low stabilization of HO˙: rationalization and prediction.

One of the most important puzzles in atmospheric chemistry is the long-lifetime of HO˙ in spite of its low-stabilization energy. In the present work, we have estimated the lifetime of HO˙ using classical dynamics simulations by coupling an available neural-network analytical potential energy surface with a chemical dynamics program. The simulation results clearly indicate that at room temperature, the lifetime of HO˙ can exceed 1 μs under collision-free conditions.

Whole transcriptome analysis identifies fusion as a novel biomarker in metastatic colorectal cancer.

Background: Colorectal cancer (CRC) is a complex, heterogeneous disease characterized by frequent relapses and metastasis. Previous studies have reported that the invasion and progression of CRC in several cases can be controlled by targeting fusion genes. This study aimed to screen for potent fusion transcripts as potential molecular biomarkers and therapeutic targets for metastatic CRC (mCRC) using an approach.

Sunlight-Assisted Photodegradation of Tetracycline Using ZnS-Melamine-Formaldehyde Nanocomposites.

The degradation of colorless tetracycline hydrochloride (TCH), a widely used antibiotic, is a significant environmental concern due to its persistence in aquatic systems. The zinc sulfide (ZnS) nanoparticle fabricated melamine-formaldehyde polymer (MFP)-based nanocomposite (ZnS-MFP) was prepared via a hydrothermal polymerization method, followed by surface modification through a simple precipitation route. The degradation of TCH through photocatalysis adheres to pseudo-first-order kinetics with a significantly faster rate under natural sunlight than under artificial bulb light.

Bio-reductive Co(iii)-doxorubicin complex for cancer cell-selective delivery of doxorubicin and potent anticancer activity.

The utility of bio-reductive prodrugs in cancer research has emerged as an attractive strategy. We synthesized and characterized a couple of cobalt(iii)-Schiff base complexes of general molecular formula Co(L)(L) and Co(L)(dox) , where L and L are ,-(ethane-1,2-diyl)bis(1-(pyridine-2-yl)methanimine) and 1-phenyl-1,3-butanedione, and dox = doxorubicin, as bio-reductive prodrugs. UV-vis and fluorescence spectroscopic assays confirmed the reductive release of doxorubicin from the complex in a GSH-dependent manner under physiological conditions, showing its potential for drug release.

Recent developments and innovative application of propolis in the food industry: a natural preservative from honeybee waste.

Unlabelled: Propolis, or bee glue, is a resinous substance produced by honeybees from plant resins, rich in bioactive compounds with antimicrobial, antioxidant, anti-cancer, anti-inflammatory, and anti-cavity properties. These qualities make it a valuable natural preservative in the food industry, extending shelf life and preventing spoilage. Propolis has gained attention as an alternative to synthetic preservatives.

Exploring the functional properties of the diamond-like quaternary compound LiZnGeS for potential energy applications: a theoretical approach.

It is anticipated that wide-bandgap semiconductors (WBGSs) would be useful materials for energy production and storage. A well-synthesized, yet scarcely explored, diamond-like quaternary semiconductor LiZnGeS has been considered for this work. Herein, we have employed two well-known functionals GGA and mGGA within a framework of density functional theory (DFT).

Optimized node-level capsule graph neural network for subject-independent emotion recognition from EEG signals.

Subject-independent emotion detection using EEG (Electroencephalography) using Vibrational Mode Decomposition and deep learning is made possible by the scarcity of labelled EEG datasets encompassing a variety of emotions. Labelled EEG data collection over a wide range of emotional states from a broad and varied population is challenging and resource-intensive. As a result, models trained on small or biased datasets may fail to generalize well to unknown individuals or emotional states, resulting in lower accuracy and robustness in real-world applications.

Decoding the Interactions Between Antibiotics and Microplastics- Chemistry, Environmental Impacts, and Mitigation Approaches- A State-of-the-Art Review.

The coexistence of antibiotics (AB) and microplastics (MP) in the environment has led to the formation of AB-MP complexes, posing several ecological and public health challenges. This review explores the mechanisms driving AB adsorption onto MPs, including diverse interactions (hydrophobic interactions, hydrogen bonding, π-π stacking, and ionic exchange) and their role in maintaining the persistence and mobility of the complexes. These complexes have been reported to serve as reservoirs/vectors for antimicrobial resistance (AMR), disrupt microbial communities, and enhance the bioavailability of ABs, thus posing various threats affecting biodiversity health and ecosystem stability.

Enhancing cybersecurity in virtual power plants by detecting network based cyber attacks using an unsupervised autoencoder approach.

The increasing adoption of the Internet of Things (IoT) in energy systems has brought significant advancements but also heightened cyber security risks. Virtual Power Plants (VPPs), which aggregate distributed renewable energy resources into a single entity for participation in energy markets, are particularly vulnerable to cyber-attacks due to their reliance on modern information and communication technologies. Cyber-attacks targeting devices, networks, or specific goals can compromise system integrity.

Identification, purification and functional characterization of a thermostable marine chitinase for potential fungal control via chitin degradation mechanism.

The growing prevalence of treatment-resistant Candida species highlights an urgent need for innovative antifungal therapies. The current range of antifungals, limited to polyenes, azoles, and echinocandins, are becoming insufficient due to the rise of resistance, including cross-resistance among fungal strains. Marine environment is an underexplored reservoir of unique enzymes which can be extremophilic.

Investigating spatiotemporal traffic dynamics toward conflict risk levels using trajectory data in heterogeneous traffic conditions.

Objective: This study aimed to identify dynamic spatiotemporal traffic factors influencing conflict risk levels on National Highways under heterogeneous traffic conditions in India. The research addresses gaps by capturing vehicle interactions using high-resolution UAV-based trajectory data and proposes a novel two-stage methodology for real-time conflict risk evaluation, moving beyond traditional binary risk classifications to a four-level framework (High, Moderate, Low, No-Risk).

Methods: Over 40,000 conflict risk sequences were classified into four severity levels using the Modified Time-to-Collision (MTTC) surrogate safety measure.

Physicochemical characterization of polyoxyethylene (POE)-based nonionic surfactants in single and mixed micellar environments for anticancer drug solubilization enhancement.

This work reports the nanoscale micellar formation in single and mixed surfactant systems by combining an amphiphilic graft copolymer, Soluplus® (primary surfactant), blended with other polyoxyethylene (POE)-based nonionic surfactants such as Kolliphor® HS15, Kolliphor® EL, Tween-80, TPGS®, and Pluronics® P123 in an aqueous solution environment. The solution behaviour of these surfactants as a single system were analyzed in a wide range of surfactant concentrations and temperatures. Rheological measurements revealed distinct solution behaviour in the case of Soluplus®, ranging from low-viscosity () and fluid-like behavior at ≤20% w/v to a highly viscous state at ≥90% w/v, where the loss modulus ('') exceeded the storage modulus (').

NgBeB : Binding of Noble Gas Through Both Cationic Beryllium and Anionic Boron Centers.

Quantum chemical calculations have been performed to investigate the structure, stability, and bonding in noble gas (Ng) bound BeB complexes. The present results show that BeB , a charge-separated [Be][B][Be] cluster, can employ both its cationic Be center and anionic B center to bind Ng atoms. It can bind a total of seven Ng atoms, resulting in the formation of a highly symmetric (Ng)Be(Ng)B complex, having D point group.

A Theoretical Investigation on the Role of Primary, Secondary, and Tertiary Amine Substituents in Excited State Intramolecular Proton Transfer of p-Amino o-Hydroxy Benzaldehyde.

This article reports a comprehensive theoretical analysis of the dual fluorescence property of three derivatives of p-amino o-hydroxy benzaldehyde molecules, namely, para-N,N-dimethylamino orthohydroxy benzaldehyde (tertiary PAOHBA), para-N-methylamino orthohydroxy benzaldehyde (secondary PAOHBA), and para-amino orthohydroxy benzaldehyde (primary PAOHBA) through ab initio calculations and excited state molecular dynamics. The results revealed that excited-state intramolecular proton transfer is responsible for the dual emission properties of such molecules. The conclusions are made based on the computed vibrational frequencies, excited state antiaromaticity, potential energy surfaces, absorption and emission spectra, and finally, from the excited state dynamics.

Deleuzo-Guattarian de-construction of the mind to re-evaluate undeath.

This article examines the cases of Jahi McMath and Poe's M. Valdemar to reconceptualize the idea of undeath from a Deleuzo-Guattarian perspective. It builds upon the ambiguity existing in defining a body in the state of 'brain death' after permanent loss of consciousness to analyze how the brain, as Deleuze and Guattari's 'partial object,' facilitates the construction of the mind as a transcendent entity.

Sodium alginate/polyvinylpyrrolidone/lapatinib-loaded Zr-metal organic framework: biocompatibility evaluation and pH-responsive drug release for oral delivery applications.

Recent advancements in drug delivery systems have transformed drug administration methods to ensure precise, targeted delivery with minimal side effects. Innovations involving polymer-metal organic frameworks can significantly improve drug stability and controlled release properties. In this study, a drug delivery system based on a zirconium metal organic framework (Zr-MOF), sodium alginate (SA), and polyvinylpyrrolidone (PVP) was developed.

Inorganic-organic γ-octamolybdate hybrids for targeted anticancer applications against MiaPaca-2 and A549 cells.

Cancer is widely recognized as one of the most critical public health challenges, transcending economic boundaries and impacting populations across all socioeconomic strata. Developing effective cancer therapies is significantly hindered by challenges such as chemotherapy-related side effects, drug resistance, and tumor metastasis, which contribute to poor prognoses for many patients. In this context, inorganic drugs, particularly polyoxomolybdate-based inorganic-organic hybrids, are emerging as promising candidates for future metallodrugs.

Organoid-Based Skin and Lung Biofilm Models, a Cutting-Edge Approach for Anti-Biofilm Research: A Mini Review.

Bacterial biofilms contribute to 60%-80% of human infections, exhibiting resistance to traditional antibiotic treatment and contributing to chronic, relapsing diseases, particularly in healthcare settings. Traditional in-vitro and in-vivo models often fail to accurately replicate the human microenvironment. This mini review highlights the emerging use of organoid-based models that are three-dimensional, self-organizing structures derived from stem cells.

Advanced photocatalytic degradation of POPs and other contaminants: a comprehensive review on nanocomposites and heterojunctions.

The environmental persistence and toxicity of pollutants such as persistent organic pollutants (POPs), synthetic dyes, and pharmaceutical residues necessitate the development of effective and sustainable remediation strategies. This review underscores the urgent need for advanced approaches to eliminate these contaminants, with a particular focus on metal oxide-based photocatalysts, such as TiO, ZnO, WO, CuO, and others. We have explored their photocatalytic mechanisms, inherent limitations, and recent advancements, such as elemental doping and heterojunction engineering, to enhance their activity under visible light.

Investigation of the impact of sulfur on the properties of CZTS nanomaterials for enhanced supercapacitor performance.

CuZnSnS (CZTS) has been synthesised using ethylene glycol as a solvent by the solvothermal method. Preliminary characterisation, like X-ray diffraction, Raman spectroscopy, and FTIR, confirmed the tetragonal structure of CZTS with kesterite phase. In the synthesis, a series of samples with different concentrations of sulfur were produced, accompanied by an in-depth analysis of structural parameters such as crystallite size and strain, utilising both the Scherrer equation and the Williamson-Hall method.

Nonaqueous capillary electrophoresis of graphene suggesting charging and dispersion mechanism in certain organic solvents.

Background: Graphene, with its unique electronic, thermal, and mechanical properties, plays an important role in electronic devices and batteries. Current applications strongly rely on liquid-phase processing, which requires stable graphene dispersions. However, stabilizing graphene dispersions in a liquid phase remains challenging because graphene easily aggregates due to strong inter-sheet forces.

Strategic use of CC bond-forming reactions for enlarging the carbon skeletal system of carbohydrate-derived platform chemicals: An overview.

Efficient conversion of biomass into hydrocarbon fuels, organic chemicals, and synthetic polymers promises sustainability of the organic chemical industries and a circular carbon economy. Synthesizing targeted bioproducts bearing more carbon atoms in their skeletal system than the parent carbohydrate molecules require strategic use of various CC bond-forming reactions (e.g.

Introducing Normalized Surface-adjusted Precipitation Index (NSPI) for regional drought assessment.

Drought is a natural event, but its frequency and severity are increasingly influenced by human activity and climate change. In the current Anthropocene era, human-induced changes to the hydrological cycle combined with natural climate variability are reshaping how droughts develop and persist. Droughts often result from complex interactions between atmospheric conditions and land surface processes, which affect how water and energy move through the environment.