Inorganic-organic γ-octamolybdate hybrids for targeted anticancer applications against MiaPaca-2 and A549 cells.

Cancer is widely recognized as one of the most critical public health challenges, transcending economic boundaries and impacting populations across all socioeconomic strata. Developing effective cancer therapies is significantly hindered by challenges such as chemotherapy-related side effects, drug resistance, and tumor metastasis, which contribute to poor prognoses for many patients. In this context, inorganic drugs, particularly polyoxomolybdate-based inorganic-organic hybrids, are emerging as promising candidates for future metallodrugs.

An α-MoO hybrid with sulfuric acid-intercalated 4,4'-bipyridine for adsorptive dye removal.

Herein, a polyoxometalate hybrid material, [MoVI3O(HSO)]·[(bpy)] (1), has been specifically designed for efficient dye adsorption. The molecular structure of 1 was elucidated single-crystal X-ray diffraction (SC-XRD), revealing a well-defined coordination network. Comprehensive characterization through FTIR, P-XRD TGA, FE-SEM, EDX mapping, XPS and zeta potential measurements confirmed the uniform distribution of constituent elements and the robust stability of 1 under operational conditions.

Polyoxometalate-supported transition metal complexes for the oxidative cross-coupling of amines and alcohols.

Three new hybrid polyoxometalates (POMs) based on transition metals, namely, copper metal with γ-[MoO] polyoxometalates [Cu(DMF)(MoO)·2CHNO]·1.8 DMF (1), cobalt metal with hexamolybdate [Co(DMSO)][MoO] (2), and nickel metal with hexamolybdate [Ni(DMSO)][MoO] (3), were developed. These materials were characterised by applying both analytical and spectroscopic techniques (IR, TGA, and CHNO elemental analysis), and structural elucidation was performed using single-crystal X-ray diffraction studies.

Insights into organic-inorganic hybrid molecular materials: organoimido functionalized polyoxomolybdates.

Polyoxometalates (POMs) are polyatomic anions that comprise transition metal group 5 (V, Nb, Ta) or group 6 (Mo, W) oxyanions connected together by shared oxygen atoms. POMs are fascinating because of their exclusive and remarkable characteristics. One of the most interesting features of POMs is their capability to function as an electron relay by performing stepwise multi-electron redox reactions while maintaining their structural integrity.