Effects of boxing exercise in people with Parkinson's disease: a systematic review.

Objective: Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by progressive changes in both motor and non-motor symptoms. Boxing exercise can improve PD symptoms. This review aimed to determine the effects of boxing exercise on lower extremity strength, balance, mobility, gait, depression, quality of life, disease severity, exercise safety, and adherence in patients with PD.

Sex-based differences in the prevention of stress-induced anxiety by Resolvin D5 and its precursor docosahexaenoic acid: A comparative study.

Acute stress can cause emotional dysregulation and trigger various molecular changes, including increased neuroinflammation in limbic regions. These changes have the potential to induce anxiety by disrupting brain physiology and functional connectivity. In this study, we investigated whether an 8-day treatment with inflammation-resolving compounds, specifically Resolvin D5 (RvD5) and its precursor, the omega-3 fatty acid docosahexaenoic acid (DHA), could alleviate anxiety induced by acute restraint stress (ARS) in male and female rats.

Toxicological assessment of niga-ichigoside F1 and 2β,3β-19α-trihydroxyursolic acid derived from (Rosaceae): determining the safety using human peripheral blood mononuclear cells (PBMC).

Chum. Schl. (Rosaceae) is used in traditional medicine as a remedy to treat diabetes and other diseases.

Role of the interleukin-33 (IL-33)/suppressor of tumorigenicity 2 (ST2) signaling in superoxide anion-triggered inflammation and pain behavior in mice.

Reactive oxygen species such as superoxide anion have varied roles in inflammation and pain, which can be mimicked by potassium superoxide (KO), the superoxide anion donor. Interleukin (IL)-33 has pleiotropic functions by activating its receptor suppression of tumorigenicity 2 (ST2). However, the role of IL-33/ST2 signaling in inflammatory pain initiated by reactive oxygen species (ROS) such as superoxide anion has not been investigated, which was the aim of the present study.

Governance and responses of health and surveillance systems to COVID-19 in BRICS countries: A scoping review protocol.

This protocol is registered on the Open Science Framework (OSF) (available at https://doi.org/10.17605/OSF.

Comparison Between Shoulder Flexed and Extended Positions in Elbow Flexion Resistance Training on Regional Hypertrophy and Maximum Strength: Preacher versus Bayesian Cable Curls.

In the present study, the effects of resistance training on regional hypertrophy and maximum strength of the elbow flexor muscles were compared between elbow flexion exercises performed with different shoulder joint angles (∼50° of flexion vs. extension) while matched for resistance profiles. In a within-subject design, 15 young men (25.

Personalising Antidepressant Treatment for Unipolar Depression Combining Individual Choices, Risks and big Data: The PETRUSHKA Tool: Personnalisation du traitement antidépresseur de la dépression unipolaire associant choix individuels, risques et mégadonnées: l'outil PETRUSHKA.

ObjectiveWe summarize the key steps to develop and assess an innovative online, evidence-based tool that supports shared decision-making in routine care to personalize antidepressant treatment in adults with depression. This PETRUSHKA tool is part of the PETRUSHKA trial (Personalize antidEpressant Treatment foR Unipolar depreSsion combining individual cHoices, risKs, and big datA).MethodsThe PETRUSHKA tool: (a) is based on prediction models, which use a combination of advanced analytics, i.

Vertical transmission of Neospora caninum from three generations of naturally infected dairy cattle from Brazil.

Neospora caninum is a major cause of abortion in dairy cattle, and vertical transmission is considered the most relevant route. The present study aimed to evaluate the vertical transmission of N. caninum from three generations of naturally infected dairy cows.

Effect of Alpha-Lipoic Acid on the Development, Oxidative Stress, and Cryotolerance of Bovine Embryos Produced In Vitro.

Oxidative stress (OS) induced by an imbalance in reactive oxygen species (ROS) levels in vitro impairs embryonic development. Here, we assessed the effects of alpha-lipoic acid (ALA) in in vitro production media on OS reduction, embryonic development, and cryotolerance of bovine embryos. We evaluated the effects of adding different concentrations of ALA (2.

in Inflammation and Pain: Update on Pathologic Mechanisms.

) is a Gram-positive bacterium of significant clinical importance, known for its versatility and ability to cause a wide array of infections, such as osteoarticular, pulmonary, cardiovascular, device-related, and hospital-acquired infections. This review describes the most recent evidence of the pathogenic potential of , which is commonly part of the human microbiota but can lead to severe infections. The prevalence of pathogenic in hospital and community settings contributes to substantial morbidity and mortality, particularly in individuals with compromised immune systems.

Are There Differences in Postural Control and Muscular Activity in Individuals with COPD and with and Without Sarcopenia?

Aim: The aim of this study was to compare balance performance and electromyographic activity in individuals with COPD, with and without sarcopenia.

Method: Thirty-five patients with COPD were classified with and without sarcopenia according to EWGSOP criteria. Balance was assessed using a force platform under four conditions: standing with feet apart and eyes opened (FHEO), eyes closed (FHEC), on an unstable surface (US), and on one leg (OLS).

Shaping ability and cyclic fatigue resistance between Genius ProFlex, ZenFlex, and TruNatomy rotary systems: an experimental study.

Objectives: The aim of this study was to investigate the efficacy of three newly introduced rotary endodontic systems: Genius ProFlex (Medidenta), TruNatomy (Dentsply Maillefer), and ZenFlex (Kerr).

Methods: Forty-five mandibular molars with root canal curvatures <5° were utilized. Micro-computed tomography scans were performed pre- and post-preparation to assess apical transportation, centralization, percentage of dentin wear, and canal volume alterations.

The Probiotication of a Lychee Beverage with : An Alternative to Dairy-Based Probiotic Products.

Probiotic vegetable-based beverages, such as lychee, can be rich in nutrients, free of cholesterol and lactose, and also have few allergenic components. is an alternative to make lychee juice a probiotic beverage. This work aimed to develop probiotic lychee beverage (LB) using by evaluating the effect of refrigerated storage on cell viability, physicochemical characteristics, and acceptance.

Analysis of choroidal markers of activity in pachychoroid disease spectrum.

Purpose: To detect choroidal markers of disease activity in eyes with chronic active unilateral pachychoroid disease spectrum (PDS) compared to the non-active contralateral eyes, based on multimodal imaging and particularly indocyanine green angiography (ICGA).

Methods: An observational retrospective case-control study. The study evaluated individuals diagnosed with chronic active unilateral PDS (group 1) by comparing the eyes with the non-active fellow eyes (group 2).

Clustering of obesogenic behaviours amongst 140 052 South American adolescents: a harmonized meta-analysis of national health surveys.

Background: Physical activity, sedentary behaviour, and diet synergically coexist (in different ways) within adolescents' lifestyles. Thus, understanding obesogenic behaviour patterns within populations is critical to promoting adolescents' health. This study investigates clustering patterns of adolescents' obesogenic behaviours across South American countries.

Effect of In Situ Acid Erosion on Structural and Optical Properties of Nanoparticulated Bisacrylic Resin With Different Surface Treatments.

Objective: To evaluate the influence of in situ acid erosion on the structural and optical properties of nanoparticulate bisacrylic resin with different surface treatments, evaluating surface roughness (Ra), knoop microhardness (KHN), color change (ΔE, ΔL, ΔC, ΔH), contrast (CR) and translucency (TP).

Methods: Eighty specimens were made (n = 10 per group) and the following surface treatments were applied: U -unpolished; A -polishing with Astropol rubber tips (Ivoclar); S -Biscover LV surface sealant (Bisco) and S -Palaseal surface sealant (kulzer). For the in situ experiment, 10 volunteers wore an intraoral appliance containing eight specimens (two specimens per experimental group), with only one specimen from each experimental group being subjected to the acid process.

Advances in intraoperative imaging in retinal diseases: A narrative review.

This review explores recent technological advances in intraoperative imaging during retinal disease surgeries, focusing on their applicability in clinical practice and impact on surgical outcomes. A literature search identified studies discussing new imaging technologies, their advantages over conventional methods, relevant case studies, and literature reviews. Exclusion criteria included studies unrelated to retinal diseases, imaging technologies not suitable for intraoperative use, outdated articles, and nonscientific reports.

Improving Soybean Germination and Nodule Development with Nitric Oxide-Releasing Polymeric Nanoparticles.

Nitric oxide (NO) is a multifunctional signaling molecule in plants, playing key roles in germination, microbial symbiosis, and nodule formation. However, its instability requires innovative approaches, such as using nanoencapsulated NO donors, to prolong its effects. This study evaluated the impact of treating soybean () seeds with the NO donor S-nitrosoglutathione (GSNO), encapsulated in polymeric nanoparticles, on the germination, nodulation, and plant growth.

Aspirin-triggered lipoxin A4 reduces neuropathic pain and anxiety-like behaviours in male diabetic rats: antinociceptive enhancement by cannabinoid receptor agonists.

Neuropathy is the most common complication of diabetes, leading to painful symptoms like hyperalgesia. Current treatments for diabetic painful neuropathy often prove inadequate, necessitating the exploration of new pharmacological approaches. Therefore, this study aimed to investigate the potential antinociceptive effect of aspirin-triggered lipoxin A4 (ATL), a specialized pro-resolving lipid mediator, when administered alone or in combination with cannabinoid agonists, to alleviate diabetic neuropathic pain.

Betalains: A Narrative Review on Pharmacological Mechanisms Supporting the Nutraceutical Potential Towards Health Benefits.

Betalains are naturally occurring pigments sourced mainly from (beetroot), spp. (dragon fruit), spp., and spp.

Protective role of TRPV1 nociceptive neurons communication to macrophages against infection in mice.

Chagas' disease is a life-threatening condition caused by . Patients with chronic disease may develop gastrointestinal, neurological, or associated neuro-digestive dysfunctions. CNS invasion by can occur in the acute phase, and its presence in the brain and cerebrospinal fluid was reported.

Do bodybuilders pose symmetrically? Lateral bias analysis in mandatory poses of Mr. Olympia Classic Physique athletes.

Athletes in bodybuilding can pose favouring one side or the other of the body while being evaluated in the contests. While previous research assessed lateral bias of posing in a variety of situations, no investigation has been conducted in bodybuilding. We analyzed the lateral posing bias of the Top 15 athletes for the mandatory poses in Classic Physique Mr.

Beneficial effects of pentoxifylline on spermatogenesis and germ cell apoptosis in stallions subjected to scrotal heat stress.

This study evaluated the effects of oral pentoxifylline on testicular biometry, histology, and gene expression in stallions subjected to scrotal heat stress. Fourteen stallions were divided into three groups: Control (CRL, n = 4), Testicular Degeneration (DEG, n = 5), and Testicular Degeneration Treated with Pentoxifylline (DEG + PTX, n = 5). Testicular degeneration was induced by scrotal insulation, twice daily, over two consecutive days (D-1 and D0).