Extended Use of Central Veno-Arterial Extracorporeal Membrane Oxygenation in Lung Transplantation for Patients with Pulmonary Arterial Hypertension.

Objectives: Lung transplantation (LTx) for patients with pulmonary arterial hypertension (PAH) is associated with high postoperative morbidity and mortality. Extracorporeal membrane oxygenation (ECMO) supports patients' haemodynamics during and after LTx. However, the optimal ECMO strategy, especially for patients with PAH, is debated.

Fully printed multimodal sensing system for continuous health monitoring during exercise.

Continuous monitoring of physicochemical information during exercise using wearable and implantable systems is critical for disease management and health monitoring. However, it remains challenging due to limited multimodal system integration, poor detection precision, and rigidity of the equipment. Herein, we present a fully printed multimodal sensing system (MSS) that integrates an implantable glucose/lactate biosensor, wearable electrocardiogram (ECG) and temperature sensors with the reusable electronics.

Improved survival with high albumin leakage in patients with protein-energy wasting and inflammation on hemodialysis and online hemodiafiltration.

Albumin leakage (Alb-L) and serum albumin (S-Alb) levels are predictors of mortality in dialysis patients. Because protein-energy wasting (PEW) and inflammation reduce hepatic albumin synthesis, we hypothesized that mortality would differ based on Alb-L and/or S-Alb levels, depending on the presence of PEW and inflammation. This retrospective study included 738 super high-flux hemodialysis (SHF HD) and online hemodiafiltration (OHDF) patients.

Evaluation of the linear and nonlinear classifiers for distinguishing between healthy subjects and patients with valvular heart diseases based on electrocardiograms, seismocardiograms, and gyrocardiograms.

Background And Objective: Heart rate variability (HRV) is a prognostic marker in numerous cardiovascular and non-cardiovascular conditions. Valvular heart disease (VHD) is a cardiovascular disease that affects the heart valves (aortic valve, mitral valve, pulmonic valve and tricupsid valve) and is the third most common cardiovascular disease. Traditional methods, such as echocardiography, computed tomography, and magnetic resonance imaging, are effective, but their limitations in outpatient monitoring have led to the exploration of alternative techniques, such as electrocardiography (ECG), seismocardiography (SCG) and gyrocardiography (SCG).

Calculation of the Optimal Angiographic View Using Intravascular Ultrasound by the Tip Detection Method.

Objectives: We aimed to calculate the optimal angiographic view from an intravascular ultrasound (IVUS) image using the tip detection (TD) method.

Key Steps: Using the TD method, we identified the orientation of the angiographic image on the IVUS image. The IVUS image was superimposed on the angiographic image.

Calculation of Absolute Blood Volume Using Intermittent Infusion Hemodiafiltration.

The absolute blood volume of dialysis patients at the start of treatment can be calculated using a method that combines continuous relative blood volume measurement and dialysate infusion. In this study, we applied this method to patients undergoing intermittent infusion hemodiafiltration. The initial absolute blood volume was measured based on the relative blood volume changes observed during each of the five intermittent dialysate infusions (dilutions).

Use of NPWTi-d for simultaneous pleural and mediastinal drainage in deep sternal wound infection during mechanical circulatory support.

This case report describes the management of deep sternal wound infection in a female patient supported with an extracorporeal left ventricular assist device (LVAD) following the Bentall procedure for acute aortic dissection. She developed pleural effusions with pathological communications between the pleural and mediastinal cavities, necessitating continuous drainage. After radical debridement, we applied negative pressure wound therapy (NPWT) with instillation and dwell time (NPWTi-d) to simultaneously drain the pleural cavities and the infected mediastinum.

Clinical note: the demagnetisation and successful re-magnetisation of a cochlear implant magnet using 3T magnetic resonance imaging.

Objective: This case report describes the successful application of a procedure to re-magnetise the cochlear implant (CI) magnet in a unilaterally implanted user with an older generation implant, following an inadvertent exposure to a higher strength magnetic resonance imaging (MRI) field for which the implant was indicated.

Design: A case report.

Study Sample: An adult with a unilateral CI (a SONATA TI100 CI).

Selective visceral perfusion in thoracoabdominal aortic surgery: optimal flow rate in a porcine model.

To determine the optimal perfusion volume for the celiac artery (CA) and superior mesenteric artery (SMA) in a porcine model. Fifteen Yorkshire pigs (46.7 ± 5.

Deep learning neural network of adenocarcinoma detection in effusion cytology.

Objective: Cytologic examination, which confirms the presence or absence of malignant cells, detects malignant cells from various organs, with adenocarcinoma as the most common histologic type. We developed a deep learning model to detect malignant cells in images obtained following effusion cytology.

Methods: The deep learning model was created using the YOLOv8 object detection algorithm (Roboflow, Inc) and 275 cases of adenocarcinoma comprising 12 182 images and 29 245 labels as well as 188 cases negative for malignancy comprising 1980 images.

A Novel Technique for Diaphragmatic Compound Motor Action Potential Monitoring Using the BeeAT Catheter During Cryoballoon Ablation for Atrial Fibrillation.

Background: Diaphragmatic compound motor action potential (CMAP) monitoring helps prevent phrenic nerve palsy during cryoballoon ablation (CBA) for atrial fibrillation.

Methods: This retrospective analysis included 95 patients who had undergone CBA. Phrenic nerve pacing was performed via the distal electrode of a BeeAT catheter positioned in the right subclavian vein, with CMAPs recorded from the most proximal electrode in the subdiaphragmatic inferior vena cava.

Preliminary Quantitative Evaluation of the Optimal Colour System for the Assessment of Peripheral Circulation from Applied Pressure Using Machine Learning.

Peripheral circulatory failure refers to a condition in which the blood flow through superficial capillaries is markedly reduced or completely occluded. In clinical practice, nurses strictly adhere to regular repositioning protocols to prevent peripheral circulatory failure, during which the skin condition is evaluated visually. In this study, skin colour changes resulting from pressure application were continuously captured using a camera, and supervised machine learning was employed to classify the data into two categories: before and after pressure.

Cell Membrane Capacitance () Measured by Bioimpedance Spectroscopy (BIS): A Narrative Review of Its Clinical Relevance and Biomarker Potential.

Cell membrane capacitance () is a potential biomarker that reflects the structural and functional integrity of cell membranes. It is essential for physiological processes such as signal transduction, ion transport, and cellular homeostasis. In clinical practice, can be determined using bioimpedance spectroscopy (BIS), a non-invasive technique for analysing the intrinsic electrical properties of biological tissues across a range of frequencies.

Transcutaneous Oxygen Tension and Bradykinin Concentration During Rheocarna Therapy: Case Series.

Introduction: Rheocarna therapy is believed to improve circulation via vasodilation; however, few reports have evaluated peripheral circulation during treatment.

Methods: Bradykinin plasma concentration, blood pressure (BP), and transcutaneous oxygen pressure (TcPO) were measured in two patients with chronic limb-threatening ischemia during Rheocarna therapy.

Results: Case 1 (wound grade 1) exhibited stable, high TcPO and no ulcer progression after 6 months.

Voluntary Exercise-Induced Skeletal Muscle Responses in Young and Aged Mice on a High-Fat Diet.

Background and objective Aging and consumption of a high-fat diet (HFD) are associated with increased body weight and reduced skeletal muscle quality. Although aerobic exercise is generally considered protective against these risks, the impact of self-initiated physical activity on an HFD in older individuals remains unclear. This study aimed to investigate the influence of spontaneous wheel-running on body weight, intramuscular fat accumulation, and mitochondrial metabolic function in the skeletal muscles of young and aged mice on HFD.

Iron Deficiency Prevention and Dietary Habits Among Elite Female University Athletes in Japan.

This study investigated the percentage of iron deficiency anemia (IDA) and iron deficiency (ID) among 71 elite female athletes at a Japanese university and assessed their dietary habits. IDA was identified in 9.9% ( = 7) of participants, and only 22.

Immunosensor Enhanced with Silver Nanocrystals for On-Chip Prostate-Specific Antigen Detection.

An electrochemical immunosensor for the quantification of prostate-specific antigens (PSAs) using silver nanocrystals (AgNCs) is reported. The silver nanocrystals were synthesized using a conventional citrate reduction protocol. The silver nanocrystals were characterized using scanning electron microscopy (SEM) and field effect scanning electron microscopy (FESEM), X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), Fourier-transform infrared spectroscopy (FTIR), UV-Vis spectroscopy, and small-angle X-ray scattering (SAXS).

Androgen Receptor-Controlled microRNA-124-3p.2 Suppresses Prostate Cancer Progression via CCL2 Inhibition.

We previously reported that androgen receptor (AR) signaling blockade induces chemotactic-C-C-motif-chemokine-ligand-2 (CCL2) secretion from prostate cancer cells and activates cancer cells through an autocrine manner. However, the mechanism of how AR negatively regulates CCL2 expression is still unclear. As various microRNAs participate in prostate cancer development, we hypothesized that there are AR-controlled miRs that regulate CCL2 production.

Exploring the emerging trends and hot topics of 5G technology application in wireless medicine: A bibliometric and visualization analysis.

Background: The online diagnosis and treatment model based on 5th generation mobile communication (5G) technology is one of the important ways to solve the imbalance between supply and demand of medical services.

Objective: We systematically summarized Chinese and English literature on the application of 5G technology in the field of wireless medical and conducted a literature feature analysis.

Methods: We used bibliometrics to quantitatively analyze the research trends and hot topics and comparatively analyzed the differences between research in China and other countries.

Multi-site feasibility and reproducibility study on UTE 3D phosphorous MRSI using novel rosette trajectory (PETALUTE).

Purpose: This study aims (1) to implement a robust acquisition, fully automated reconstruction, and processing pipeline using a novel rosette k-space pattern for UTE P 3D MRSI and (2) to evaluate the clinical applicability and reproducibility at different experimental setups.

Methods: A multi-center feasibility/reproducibility study was conducted for the novel UTE P 3D MRSI sequence with rosette petal trajectory (PETALUTE) at three institutions with different experimental setups (Siemens Prisma with volume head coil or surface coil, Siemens Biograph mMR with volume head coil). Five healthy subjects at each site were measured with an acquisition delay of 65 μs and a final resolution of 10 × 10 × 10 mm in 9 min.

Open-access ultrasonic diaphragm dataset and an automatic diaphragm measurement using deep learning network.

Background: The assessment of diaphragm function is crucial for effective clinical management and the prevention of complications associated with diaphragmatic dysfunction. However, current measurement methodologies rely on manual techniques that are susceptible to human error: How does the performance of an automatic diaphragm measurement system based on a segmentation neural network focusing on diaphragm thickness and excursion compare with existing methodologies?

Methods: The proposed system integrates segmentation and parameter measurement, leveraging a newly established ultrasound diaphragm dataset. This dataset comprises B-mode ultrasound images and videos for diaphragm thickness assessment, as well as M-mode images and videos for movement measurement.

Modeling Intershot Variability for Robust Temporal Subsampling of Dynamic, GABA-Edited MR Spectroscopy Data.

Variability between individual transients in an MRS acquisition presents a challenge for reliable quantification, particularly in functional scenarios where discrete subsets of the available transients may be compared. The current study aims to develop and validate a model for removing unwanted variance from GABA-edited MRS data, while preserving variance of potential interest-such as metabolic response to a functional task. A linear model is used to describe sources of variance in the system: intrinsic, periodic variance associated with phase cycling and spectral editing, and abrupt changes associated with subject movement.

Impact of three-dimensional prostate models during robot-assisted radical prostatectomy on surgical margins and functional outcomes.

Background: Robot-assisted radical prostatectomy (RARP) is the standard surgical procedure for the treatment of prostate cancer. RARP requires a trade-off between performing a wider resection in order to reduce the risk of positive surgical margins (PSMs) and performing minimal resection of the nerve bundles that determine functional outcomes, such as incontinence and potency, which affect patients' quality of life. In order to achieve favourable outcomes, a precise understanding of the three-dimensional (3D) anatomy of the prostate, nerve bundles and tumour lesion is needed.

Body Composition and Metabolic Profiles in Young Adults: A Cross-Sectional Comparison of People Who Use E-Cigarettes, People Who Smoke Cigarettes, and People Who Have Never Used Nicotine Products.

: Recent research highlights uncertainties surrounding the metabolic effects of nicotine in young adults, particularly among people who use e-cigarettes. While traditional smoking is known to alter body composition, the metabolic impact of using e-cigarettes remains less understood. : In this cross-sectional study, body composition (via bioelectrical impedance analysis) and lifestyle data were collected from 60 university students (mean age: 21.

The Role of [18F]FDG PET Imaging for the Assessment of Pulmonary Lymphangitic Carcinomatosis: A Comprehensive Narrative Literature Review.

: Pulmonary lymphangitic carcinomatosis (PLC) is a rare, aggressive manifestation of metastatic cancer characterized by lymphatic infiltration of the lungs, typically indicating advanced disease and poor prognosis. : This comprehensive narrative review evaluates the role of [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) imaging in assessing PLC. : Current evidence demonstrates that [18F]FDG PET/CT achieves high diagnostic accuracy, with sensitivity and specificity ranging from 86 to 97% and 84 to 100%, respectively, particularly when employing semiquantitative metrics such as peritumoral standardized uptake value (SUVmax) thresholds (e.