Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The association between asthma and chronic obstructive pulmonary disease overlap (ACO) and insulin resistance (IR) has not been adequately investigated. Triglyceride glucose (TyG) index-related obesity indices offer a novel measure for assessing IR. We aimed to explore the associations between these indices and ACO in US population. Data used in this study were obtained from the National Health and Nutrition Examination Survey. We performed logistic regression analysis, restricted cubic spline modeling, subgroup analysis, sensitivity analysis, and additional analyses to examine the association between TyG-related obesity indices and ACO. The study involved 11,453 participants. TyG-waist to height ratio, TyG-body mass index, TyG-weight adjusted waist index, and TyG-waist circumference were all associated with ACO in multivariate logistic regression, with adjusted odds ratios (ORs) (95% confidence interval [CI]) of 1.23 (1.11-1.37), 1.32 (1.12-1.57), 1.20 (1.08-1.34), 1.14 (1.06-1.22), respectively. The highest quartile of all indices had the strongest link with ACO, as evidenced for TyG-waist to height ratio (OR [95% CI] = 1.80 [1.29-2.52]), TyG-body mass index (OR [95% CI] = 1.59 [1.19-2.14]), TyG-weight adjusted waist index (OR [95% CI] = 1.82 [1.23-2.69]), and TyG-waist circumference (OR [95% CI] = 1.75 [1.28-2.39]) in the fully adjusted model. Most subgroup, sensitivity, and supplementary analyses revealed similar results. TyG-related obesity indices were significantly associated with ACO. This finding indicates a strong correlation between high IR and susceptibility to ACO in the US population.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/MD.0000000000044294 | DOI Listing |
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419257 | PMC |
Publication Analysis
Top Keywords
Similar Publications
The Comparative Effects of White Potato and White Rice Consumption on Measures of Cardiometabolic Health in Individuals with Type 2 Diabetes Mellitus and Features of Metabolic Syndrome.
Curr Dev Nutr
September 2025
Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL, United States.
Background: The objective of this study was to compare the effects of daily consumption of white potatoes compared with white rice on cardiometabolic health in individuals with type-2 diabetes (T2D).
Objective: To determine the effects of white potato consumption compared to white rice (a commonly consumed refined grain) on indices of glycemic control and cardiovascular health in individuals with overweight or obesity and T2D.
Methods: In this randomized crossover study, comparative control trial, 24 adults with T2D [45-80 y, body mass index (kg/m) 25-40] consumed baked white potatoes (100 g) or calorie-matched white rice (75 g) daily for 12 wk, separated by a 2-wk washout, with assessments of glycemic control, lipids, inflammation, blood pressure, endothelial function, and body composition at baseline (only 1 baseline visit included as a covariate in statistical analyses), 6 wk, and 12 wk.
Longitudinal changes in bodyweight, body condition, and muscle condition in ageing pet cats: findings from the Cat Prospective Ageing and Welfare Study.
Front Vet Sci
August 2025
Department of Musculoskeletal Biology and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.
Body composition metrics such as bodyweight, body condition score (BCS) and muscle condition score (MCS) can be readily recorded as part of veterinary examinations in ageing cats. However, the description of how these parameters change with age, whilst accounting for sex and age-related morbidity, is limited. The aim of this prospective cohort study was to evaluate age, sex and health-related changes in bodyweight, BCS and MCS in client-owned pet cats.
View Article and Find Full Text PDFEfficacy of lifestyle modification combined with GLP-1 receptor agonists on body weight and cardiometabolic biomarkers in individuals with overweight or obesity: a systematic review and meta-analysis.
EClinicalMedicine
October 2025
Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are established treatments for obesity. However, it remains inconclusive whether the combination of lifestyle modifications and GLP-1RA interventions can lead to greater weight loss and better control of cardiovascular biomarkers. We aimed to evaluate the efficacy of this combination therapy on weight loss and cardiometabolic markers in adults with overweight or obesity.
View Article and Find Full Text PDFCross-sectional study on exercise capacity in obese patients with severe obstructive sleep apnea syndrome.
Front Physiol
August 2025
Department of Rehabilitation Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Objective: To explore the exercise capacity in obese patients with severe obstructive sleep apnea syndrome (OSAS) through cardiopulmonary exercise test (CPET).
Methods: In this cross-sectional study, patients with simple obesity (36 cases) and obese patients with severe OSAS (45 cases) admitted to the Department of Rehabilitation Medicine and the Department of General Practice of the Affiliated Wuxi People's Hospital of Nanjing Medical University from September 2019 to January 2024 were collected. Additionally, we included 33 patients (BMI<28 kg/m,AHI<5/hour) as a control group.
The Association Between Obesity and Depressive Symptoms: Mediation by C-Reactive Protein and Neutrophil-to-Lymphocyte Ratio.
Alpha Psychiatry
August 2025
Department of Mental Health, The Second Hospital of Lanzhou University, 730000 Lanzhou, Gansu, China.
Background: Obesity and depressive disorders are significant public health concerns, and their association is well-documented. This study investigates the role of inflammatory markers, specifically C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR), in mediating the relationship between obesity and depressive symptoms.
Methods: We utilized data from 37,538 adults from the National Health and Nutrition Examination Survey (NHANES), covering the period from 2005 to March, 2020, pre-pandemic.