Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Postoperative complications significantly impact outcomes in head and neck free-flap reconstruction. The comprehensive complication index (CCI) offers a continuous measure of complication burden but is rarely applied in head and neck surgery compared to the Clavien-Dindo Classification (CDC).
Methods: This retrospective study analyzed 354 patients who underwent head and neck free-flap reconstruction. Complications were graded using the CDC, and the CCI was calculated. Multivariable linear regression was used to identify risk factors for increased CCI values.
Results: A total of 413 complications were observed in 252 patients. Analysis using the CCI identified mandibular reconstruction, diabetes mellitus, and prolonged operative time as significant risk factors for increased complication burden, while analysis using the CDC identified only prolonged operative time.
Conclusions: The CCI provides a comprehensive assessment of postoperative morbidity and demonstrates potential for improved evaluation of complication burden in head and neck free-flap reconstruction.
Level Of Evidence: Level IV.
Clinical Trial Registration: This study was registered in the UMIN Clinical Trials Registry as UMIN000055625 (http://www.umin.ac.jp/ctr).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jso.70077 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Demystifying the link between periodontitis and oral cancer: a systematic review integrating clinical, pre-clinical, and in vitro data.
Cancer Metastasis Rev
September 2025
Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 North University Ave, Room G018, Ann Arbor, MI, 48109-1078, USA.
Chronic inflammation and microbial dysbiosis have been implicated in the development of head and neck squamous cell carcinoma (HNSCC), particularly oral cavity squamous cell carcinoma (OSCC). Periodontitis is a common chronic inflammatory disease characterized by the progressive destruction of tooth-supporting structures. While periodontitis Has been associated with an increased risk of OSCC in epidemiological and mechanistic studies, the strength of this association is unclear.
View Article and Find Full Text PDF5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
Lasers Med Sci
September 2025
Department of Otolaryngology Head and Neck Surgery, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, 71 Hexi Street, Nanjing 210019, Jiangsu, China.
To evaluated the efficacy of photodynamic therapy (PDT) in improving laryngeal mucosal wound scar healing in vivo and investigated its underlying mechanisms. Laryngeal mucosal wounds were induced in Sprague-Dawley rats. Two weeks post-injury, PDT was administered via intraperitoneal injection of 100 mg/kg 5-aminolevulinic acid (5-ALA) and 635-nm red laser irradiation at varying energy doses (15, 30, and 45 J/cm²).
View Article and Find Full Text PDFRecessive variants in TWNK cause syndromic and non-syndromic post-synaptic auditory neuropathy through MtDNA replication defects.
Hum Genet
September 2025
College of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, 28 Fuxing Road, Beijing, 100853, China.
Recessive variants in TWNK cause syndromes arising from mitochondrial DNA (mtDNA) depletion. Hearing loss is the most prevalent manifestation in individuals with these disorders. However, the clinical and pathophysiological features have not been fully elucidated.
View Article and Find Full Text PDFGlobal, regional and national burdens of mental disorders, substance use disorders and self-harm among adolescents and young adults, 1990-2021: a systematic analysis for the Global Burden of Diseases Study 2021.
Eur Arch Psychiatry Clin Neurosci
September 2025
School of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Concerns over the mental health among young people have been increasing recently. We aimed to estimate the burdens of mental disorders, substance use disorders (SUDs), and self-harm at global, regional and national levels among adolescents and young adults aged 10-24 years from 1990 to 2021. Incidence, prevalence, and disability-adjusted life years (DALYs) of mental disorders, SUDs, and self-harm among young people were examined by age, sex, region, and country/territory.
View Article and Find Full Text PDFVocal tract contribution to vocal intensity: Interaction between vocal fold adduction, formant tuning, and fundamental frequency.
J Acoust Soc Am
September 2025
Department of Head and Neck Surgery, University of California, Los Angeles, 31-24 Rehab Center, 1000 Veteran Avenue, Los Angeles, California 90095-1794, USA.
The goal of this study was to understand the interaction between the voice source spectral shape, formant tuning, and fundamental frequency in determining the vocal tract contribution to vocal intensity. Computational voice simulations were performed with parametric variations in both vocal fold and vocal tract configurations. The vocal tract contribution to vocal intensity was quantified as the difference in the A-weighted sound pressure level between the radiated sound pressure and the sound pressure at the glottis.
View Article and Find Full Text PDF