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Despite humanity's many lunar missions to the equatorial and mid-latitude regions, the south pole remains uncharted because of its exceptionally harsh conditions. The quest for water ice and the drive to establish lunar bases have positioned the south pole area above 80° latitude, characterized by permanently shaded regions and conducive to water ice preservation. However, the daunting terrain and intricate illumination in this area present significant challenges to engineering safety. Here, we introduce a Landing Feasibility Probability (LFP) model to evaluate the viability of potential landing sites. We pinpoint 120 prospective landing sites, stratified into 25 high-priority, 64 medium-priority, and 31 low-priority sites. These sites, encompassing a mere 0.6 % of the lunar south pole, have been rigorously vetted against 10 critical factors for landing feasibility. These sites show a pronounced clustering around 8 major craters and plateaus, organizing into 7 lunar site networks, with each network comprising 4 sites with a maximum dimension under 25 km, ideal for the development of lunar bases and observational networks. The LFP model's selection process is derived from a heuristic Genetic Algorithm (GA) informed by expert experience. The landing sites are strategically positioned to address the dual challenges of scientific goals and engineering safety at the lunar south pole, while also providing site selection guidance and facilitating international collaboration and communication for lunar expeditions. This method can also be adapted for site selection on other celestial bodies (e.g. Mars and asteroids) for scientific exploration and construction of extraterrestrial bases.
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http://dx.doi.org/10.1016/j.scib.2025.08.035 | DOI Listing |
Sci Bull (Beijing)
August 2025
College of Surveying and Geo-Informatics, Tongji University, Shanghai 200092, China; Tiandu-Tongji University Deep Space Exploration Joint Laboratory, Tongji University, Shanghai 200092, China; Shanghai Key Laboratory for Planetary Mapping and Remote Sensing for Deep Space Exploration, Tongji Univer
Despite humanity's many lunar missions to the equatorial and mid-latitude regions, the south pole remains uncharted because of its exceptionally harsh conditions. The quest for water ice and the drive to establish lunar bases have positioned the south pole area above 80° latitude, characterized by permanently shaded regions and conducive to water ice preservation. However, the daunting terrain and intricate illumination in this area present significant challenges to engineering safety.
View Article and Find Full Text PDFOphthalmol Glaucoma
September 2025
NIHR Moorfields Biomedical Research Centre, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, England; Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Purpose: To compare the long-term safety of MicroShunt implantation with trabeculectomy in eyes with primary open-angle glaucoma (POAG).
Methods: This was a 3-year observational extension of a 2-year prospective randomized trial comparing clinical outcomes of MicroShunt implantation with trabeculectomy, both augmented with mitomycin C. Adverse events (AEs), intraocular pressure (IOP), and IOP-lowering medication use were recorded 36, 48, and 60 months after initial randomization.
Epilepsia
August 2025
Department of Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.
The acceptability and validity of the term "psychogenic nonepileptic seizures" (PNES) have been questioned. Currently, numerous alternative terms, such as "conversion," "dissociative," "functional," "attacks," and "events," are used in both medical literature and clinical practice, leading to confusion among professionals and patients. The lack of a uniform diagnostic label is likely to impede research funding and service development.
View Article and Find Full Text PDFNat Hum Behav
August 2025
Department of Child and Adolescent Psychiatry, Robert Debré Hospital, APHP, Paris, France.
The use of complementary, alternative and integrative medicine (CAIM) is highly prevalent among autistic individuals, with up to 90% reporting having used CAIM at least once in their lifetime. However, the evidence base for the effects of CAIM for autism remains uncertain. Here, to fill this gap, we conducted an umbrella review of meta-analyses exploring the effects of CAIM in autism across the lifespan and developed a web platform to disseminate the generated results.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Earth, Environmental and Resources Sciences (DiSTAR), University of Naples Federico II, Naples, 80126, Italy.
Rugged terrains and remote desert environments present notable challenges for geological data analyses due to limited accessibility and scarcity of surface and subsurface data. One of such challenging areas is Wadi Dif, located in South Eastern Desert (SED) of Egypt. This study presents an integrated approach combining aeromagnetic and remote sensing data to effectively investigate such environments.
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