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In the present study, the effectiveness of atmospheric pressure cold plasma (APCP) in reducing aflatoxins (AFB, AFB, AFG, and AFG) and total aflatoxin in naturally contaminated and spiked mixed nuts as well as in standard toxin solutions was investigated. According to the results, after 16 min of APCP treatment, AFB levels decreased by 24.6 % in naturally contaminated nuts and by 88.4 % in spiked samples, while an 80.9 % reduction was observed in standard toxin solutions after just 2 min. The total aflatoxin levels decreased by 22.7 % in naturally contaminated samples within 16 min, while this rate was 72.6 % in spiked samples. Considering the standard toxin solution, a rapid 76.3 % decrease was observed in total aflatoxin level in just 2 min. While APCP slightly affected moisture, free fatty acid, and peroxide values, other quality parameters remained stable. These results demonstrate that mycotoxin form and food matrix significantly influence detoxification efficiency.
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http://dx.doi.org/10.1016/j.foodchem.2025.146203 | DOI Listing |
Anal Methods
September 2025
Jilin Province Product Quality Supervision and Inspection Institute, Changchun 130103, China.
A method for determination of ten kinds of sweeteners in soybean products by multi-plug filtration cleanup (-PFC) combined with ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was established. The sample was extracted with acetonitrile (containing 1% formic acid), degreased by using -hexane liquid-liquid extraction and purified by solid phase extraction using an -PFC column (Oasis PRiME HLB). The analytes were separated by using a Waters ACQUITY UPLC® BEH C (2.
View Article and Find Full Text PDFEur J Clin Pharmacol
September 2025
Department of Hospital Pharmacy, Meander Medical Centre, Amersfoort, the Netherlands.
Purpose: This study was designed to analyse the influence of temperature, pH and storage time on unbound fractions of PHT and VPA.
Methods: The influence of ultrafiltration (UF) temperature on measured unbound fractions of PHT and VPA in spiked samples was evaluated in a single laboratory experiment and in data from a national external quality control (EQC) database. The influence of pH adjustment with phosphate buffered saline (PBS) on measured unbound fractions of PHT and VPA was investigated in patient samples.
J Proteome Res
September 2025
Center for Proteomics and Metabolomics, Leiden University Medical Center, Postbus 9600, 2300 RC Leiden, The Netherlands.
Plasma proteomics has regained attention in recent years through advancements in mass spectrometry instrumentation and sample preparation as well as new high-throughput affinity-based technologies. Here, we evaluate the analytical performance of the new Olink Reveal platform, a proximity extension assay (PEA)-based technology quantifying 1034 proteins and covering many biological pathways, in particular immune system processes. Using spiked-in recombinant Interleukin-10 (IL-10) and vascular endothelial growth factor D (VEGF-D) in the NIST SRM 1950 plasma standard, we assessed the linearity, sensitivity, precision, and accuracy of the Olink Reveal assay.
View Article and Find Full Text PDFMikrochim Acta
September 2025
College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, 712100, Shaanxi, China.
Salmonella typhimurium (S. typhimurium) A dual-mode colorimetric/photothermal immunochromatographic strip (ICS) employing hollow polydopamine nanoparticles (h-PDA) is reported for the ultrasensitive detection of Salmonella typhimurium (S. typhimurium).
View Article and Find Full Text PDFMikrochim Acta
September 2025
Teaching & Research Department of Common Course, Shenyang Sport University, Shenyang, 110115, China.
A surface enhanced Raman scattering (SERS)-based sensing platform is devised integrating a TMB redox system for rapid dopamine detection. Gold nanobipyramids (Au NBPs), synthesized via the heat-mediated seed-mediated growth method, possess dual functionality of peroxidase-like activity and SERS activity. This enables them to catalyze the oxidation of TMB and simultaneously amplify the Raman signal of the oxidized TMB product (oxTMB).
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