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The Framingham risk score (FRS) is used to assess an individual's risk of developing coronary heart disease (CHD) within 10 years by evaluating CHD risk factors. Despite the increasing mortality rate from CHD, there are limited studies examining the association between the atherogenic coefficient (AC), atherogenic index of plasma (AIP), dietary intake (assessed using a food frequency questionnaire), and FRS-CHD in Korea. The FRS is based on the following coronary risk factors: age, sex, total cholesterol, high-density lipoprotein cholesterol, smoking habits, and systolic blood pressure. The present study aimed to examine the factors that increase the risk of developing CHD in middle-aged men using the FRS based on the 2014-2015 Korea National Health and Nutrition Examination Survey (KNHANES). Data from 1,478 middle-aged men who participated in the 2014-2015 KNHANES were used. As the AC [odds ratio (OR), 6.06; 95% confidence interval (CI), 4.38-8.38; <0.001] and AIP (OR, 3.93; 95% CI, 1.93-8.01; <0.001) increased by 1 unit, the risk of developing CHD was significantly higher in the high-risk group than in the low-risk group after adjusting for potential confounding factors. In the high-risk group, the CHD risk decreased with an increase in egg intake per serving (OR, 0.84; 95% CI, 0.75-0.94; <0.01). The AC, AIP, and egg intake were potent determinants of the high-risk group compared with the low-risk group. Blood cholesterol levels and diet control can decrease the CHD risk in the next 10 years.
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http://dx.doi.org/10.3746/pnf.2025.30.4.295 | DOI Listing |
J Clin Ultrasound
September 2025
Hebei General Hospital, Shijiazhuang, China.
Background: Acute ischemic stroke (AIS) is characterized by high incidence, sudden onset, and often poor prognosis. Carotid atherosclerosis plays a crucial role in its pathogenesis, and ultrasound imaging offers a non-invasive method for evaluating carotid plaque characteristics. This study aimed to develop and validate a prediction model for AIS risk based on a novel ultrasound-based carotid plaque scoring system combined with clinical risk factors.
View Article and Find Full Text PDFNpj Ment Health Res
September 2025
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin (Campus Charité Mitte), Berlin, Germany.
Loneliness is a growing global health issue, yet real-time assessments of its objective risk and protective factors are limited. This study identifies momentary and daily predictors using digital phenotyping and temporal analysis. Analyzing 12788 momentary observations from social mobile sensing and actigraphy, we examined how they impact loneliness on average (between-person) and in daily fluctuations (within-person).
View Article and Find Full Text PDFEye (Lond)
September 2025
Department of Anesthesiology, Chi Mei Medical Center, Liouying, Tainan city, Taiwan.
Background: Diabetic retinopathy (DR) is the leading cause of preventable blindness. Although hyperglycaemia is the primary driver, other modifiable risk factors may contribute to DR development. This study investigated the association between haemoglobin levels and DR risk in adults with type 2 diabetes.
View Article and Find Full Text PDFBr J Cancer
September 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Background: Studies examining the association of chronic kidney disease (CKD) with cancer risk have demonstrated conflicting results.
Methods: This was an individual participant data meta-analysis including 54 international cohorts contributing to the CKD Prognosis Consortium. Included cohorts had data on albuminuria [urine albumin-to-creatinine ratio (ACR)], estimated glomerular filtration rate (eGFR), overall and site-specific cancer incidence, and established risk factors for cancer.
Nutr Metab Cardiovasc Dis
July 2025
Instituto de Investigación e Innovación Biomédica de Cádiz, (INiBICA), Cádiz, Spain; GALENO Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Puerto Real, Cadiz, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain; UGC
Aims: The prevalence of metabolic syndrome (MetS) is increasing annually across all age groups, raising the risk of morbidity, mortality, diabetes and cardiovascular disease in adults, adolescents, and children. Active commuting (AC) provides an opportunity to increase physical activity and reduce the MetS risk. The purpose of this study was to synthesize the available evidence on the prevalence of MetS and MetS risk factors in relation to AC vs non-active commuting among adults, adolescents, and children.
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