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Loneliness is a growing global health issue, yet real-time assessments of its objective risk and protective factors are limited. This study identifies momentary and daily predictors using digital phenotyping and temporal analysis. Analyzing 12788 momentary observations from social mobile sensing and actigraphy, we examined how they impact loneliness on average (between-person) and in daily fluctuations (within-person). Instant messenger app usage was associated with increased loneliness, both momentarily (B = 2.95, p = 0.017) and daily (B = 2.83, p = 0.018), within and between subjects. Social media usage was associated with higher within-person momentary loneliness (B = 0.53, p = 0.001). An exploratory network analysis suggested that physical activity is associated with in-person social interaction, which is negatively associated with loneliness, while social media may replace social interactions. Thus, objective risk factors include increased use of social media and instant messaging, whereas greater physical activity may serve as a protective factor.
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http://dx.doi.org/10.1038/s44184-025-00148-4 | DOI Listing |
Pituitary
September 2025
Facoltà Di Medicina E Chirurgia, Università Cattolica del Sacro Cuore, Rome, Italy.
Introduction: Pituitary adenomas (PAs) are generally benign neoplasms, though in rare cases may exhibit aggressive behavior. In 2024, the PANOMEN-3 workshop released a new clinical-pathological classification. The objective of this study was to examine the potential of the PANOMEN-3 classification to predict prognosis of PAs and guide treatment in our single center cohort of patients with PAs.
View Article and Find Full Text PDFNutr Clin Pract
September 2025
Nutrition Department, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Background: Early diagnosis of malnutrition is essential for rapid decision-making regarding nutrition care to improve patient outcomes. We aimed to evaluate the prevalence of malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to assess the association of GLIM with 1-year mortality and length of hospital stay (LOS) in patients admitted to an emergency department (ED).
Methods: Prospective cohort study conducted in the ED of a university hospital.
Ann Surg Oncol
September 2025
Department of Surgery, Komfo Anoyke Teaching Hospital, Kumasi, Ghana.
The International Center for the Study of Breast Cancer Subtypes (ICSBCS) has played a vital role in defining and overcoming many inequities that exist in breast cancer treatment and outcome on a global basis through capacity-building programs that improve the management of breast cancer patients across the African diaspora. ICSBCS activities also fill critical gaps in disparities research related to the genetics of ancestry. Over the past 20 years, ICSBCS teams have spearheaded landmark studies documenting the relevance of genetic African ancestry to breast cancer risk, while also improving the quality of care delivered to patients in diverse communities.
View Article and Find Full Text PDFInt J Obes (Lond)
September 2025
Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Objective: To systematically evaluate the association between anthropometric parameter and myopia in children and adolescents.
Methods: PubMed, Web of Science, EBSCO, Embase, CNKI, CBM, WanFang Data, and VIP databases were searched from inception to June, 2025. We collected cross-sectional studies on the association between anthropometric parameter and myopia in children and adolescents aged 0-25 years, including body mass index (BMI) and weight-adjusted waist index (WWI).
Npj Ment Health Res
September 2025
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin (Campus Charité Mitte), Berlin, Germany.
Loneliness is a growing global health issue, yet real-time assessments of its objective risk and protective factors are limited. This study identifies momentary and daily predictors using digital phenotyping and temporal analysis. Analyzing 12788 momentary observations from social mobile sensing and actigraphy, we examined how they impact loneliness on average (between-person) and in daily fluctuations (within-person).
View Article and Find Full Text PDF