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Although ischemic stroke in infants is not very common, it remains one of the causes of morbidity and mortality in children. One of the etiologies is Moyamoya disease, which remains a rare entity in Morocco. Management of this disease in the pediatric population remains precarious due to delayed diagnosis, given the diversity of clinical presentations and the lack of necessary technical means, such as MRI or angiography, allowing early diagnosis, as well as the lack of standardized international rehabilitation protocols and the absence of pediatric rehabilitation structures in underdeveloped countries. Through this case report of a four-month-old infant who suffered an ischemic stroke in a Moyamoya, we discuss the diagnostic difficulties and its rehabilitation challenges.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398300 | PMC |
http://dx.doi.org/10.7759/cureus.89133 | DOI Listing |
J Am Heart Assoc
September 2025
Department of Neurosurgery Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences Beijing China.
Background: The cellular composition and molecular mechanisms of the pathological arteries in Moyamoya disease (MMD) remain poorly understood. To improve our understanding of pathogenesis in MMD, we aimed to comprehensively map the cellular composition and molecular alterations within the pathological arteries of patients with MMD.
Methods: Superficial temporal artery samples were collected from patients with MMD (n=2) and healthy controls (n=3), yielding a total of 26 371 cells that were used for single-cell RNA sequencing.
Int J Surg
September 2025
Department of Neurosurgery, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.
Medicine (Baltimore)
August 2025
Department of Anesthesiology, Peking University International Hospital, Beijing, China.
Moyamoya disease (MMD) patients often experience cognitive dysfunction following vascular bypass surgery, with anesthesia potentially influencing recovery. This study aims to evaluate the effects of IVA and combined intravenous and inhalational anesthesia (CIA) on cognitive recovery in MMD patients and explore influencing factors. We included 120 MMD patients who underwent vascular bypass surgery from January 1, 2021, to January 31, 2023.
View Article and Find Full Text PDFCureus
July 2025
Physical Medicine and Rehabilitation, Mohammed VI University Hospital, Oujda, MAR.
Although ischemic stroke in infants is not very common, it remains one of the causes of morbidity and mortality in children. One of the etiologies is Moyamoya disease, which remains a rare entity in Morocco. Management of this disease in the pediatric population remains precarious due to delayed diagnosis, given the diversity of clinical presentations and the lack of necessary technical means, such as MRI or angiography, allowing early diagnosis, as well as the lack of standardized international rehabilitation protocols and the absence of pediatric rehabilitation structures in underdeveloped countries.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Neurosurgery, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Objective: Superficial temporal artery-middle cerebral artery (STA-MCA) bypass, characterized by side-to-side (S-S) anastomosis, has been beneficial in reducing the incidence of postoperative complications and recurrent stroke in patients with moyamoya disease (MMD). However, the safety and efficacy of this unconventional S-S procedure remain unclear. This research aimed to investigate the clinical and hemodynamic outcomes associated with the S-S technique.
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