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Health disparities in pediatric, adolescent, and young adult (AYA) oncology remain a significant challenge, with socioeconomic status, geographic location, race, and ethnicity contributing to unequal access to care and poorer outcomes. Emerging technologies, including artificial intelligence (AI) and immersive tools such as virtual and augmented reality (VR/AR), offer transformative solutions to address these inequities. AI has demonstrated potential in enhancing diagnostic accuracy, tailoring treatment plans, and providing personalized patient navigation to guide families through complex care pathways. Immersive technologies have shown promise in delivering equitable, supportive care, including VR-based psychological support, pain management, physical rehabilitation, and patient education. This paper explores how integrating AI and immersive technology tools into cancer care can enhance quality of life and bridge gaps in care delivery for pediatric and AYA patients. Additionally, the increasing availability of internet-enabled devices presents an unprecedented opportunity to overcome traditional barriers to care in underserved populations. The paper also addresses critical challenges, including the digital divide, ethical considerations, and cost barriers, while proposing strategies for equitable implementation. By leveraging these technologies, healthcare providers can create more inclusive and effective treatment environments, ensuring that the benefits of innovation reach all patients, regardless of background or circumstance.
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http://dx.doi.org/10.1002/pbc.31909 | DOI Listing |
Pediatr Transplant
November 2025
Division of Urology, University of Toronto, Toronto, Canada.
Introduction: Differentiating acute tubular necrosis (ATN) from rejection in pediatric kidney transplant (KT) recipients remains challenging and necessitates invasive biopsy. Doppler ultrasound-derived resistive index (RI) is a noninvasive modality to assess graft status, but its diagnostic utility in children is unclear. This study evaluates RI's ability to distinguish ATN and rejection in KT.
View Article and Find Full Text PDFFront Immunol
September 2025
Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Introduction: Anti-N-methyl-D-aspartate receptor (NMDA-R) encephalitis is a neuropsychiatric disorder with additional psychiatric features caused by NMDA-R immunoglobulin G (IgG) antibodies in cerebrospinal fluid (CSF). This report presents the follow-up of a patient in whom we assumed mild NMDA-R encephalitis in the first psychotic episode.
Case Study: A patient with a prior episode of an acute polymorphic psychotic syndrome relapsed five and a half years later following a severe COVID-19 infection.
Front Immunol
September 2025
Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan.
Introduction: Human papillomavirus (HPV) infection has been implicated in autoimmune processes, yet concerns remain about the potential autoimmune risks of HPV vaccination. Juvenile idiopathic arthritis (JIA) is a chronic autoimmune condition that typically manifests in childhood. The relationship between HPV vaccination and the development of JIA remains uncertain.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Introduction: Synovial sarcoma (SS) is one of the most prevalent malignant soft tissue sarcomas in children and adolescents. Pediatric populations often present with atypical features, complicating the differentiation from benign intramuscular venous malformations (VMs).
case Presentation: An 11-year-old male with a four-year history of progressive right plantar pain and a compressible intramuscular mass.
Front Endocrinol (Lausanne)
September 2025
Department of Pediatrics, Faculty of Medicine, The Hashemite University, Zarqa, Jordan.
Background: Short stature is associated with psychological and emotional challenges, yet its impact on children's behavioral well-being in Jordan remains underexplored. This study examines the association between short stature and behavioral and emotional difficulties in Jordanian children.
Methods: A cross-sectional study was conducted at Prince Hamza Hospital, Amman (2023-2024).