Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372373 | PMC |
| http://dx.doi.org/10.1186/s12967-025-06943-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Astragalus polysaccharides restore neutrophil functions and gut microbiota homeostasis in dairy cows with subclinical ketosis.
J Dairy Sci
September 2025
State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun 130062, China. Electronic address:
Subclinical ketosis (SCK) in periparturient cows is associated with gut microbiota dysbiosis and energy metabolism disorders. Although in vitro studies show that free fatty acids (FFA) and BHB impair polymorphonuclear neutrophil (PMN) functions-potentially causing secondary infections-limited in vivo evidence exists. Astragalus polysaccharides (APS) modulate metabolism, immunity, and gut microbiota, but their effects on PMN functions and gut microbiota in SCK cows remain unclear.
View Article and Find Full Text PDFMicrobiota-dependent formylated peptide receptor (Fpr1/2) signaling regulates enteric nervous system development and gastrointestinal motility in mice.
Cell Mol Gastroenterol Hepatol
September 2025
Department of Pathology & Laboratory Medicine, Emory University, Atlanta, USA. Electronic address:
Background & Aims: Formylated peptide receptors 1 and 2 (Fpr1/2 or FPRs) are G-protein-coupled pattern recognition receptors that bind bacterial formylated peptides. The role of FPRs in enteric nervous system (ENS) development and gastrointestinal (GI) motility is unknown.
Methods: We generated mice with germline, epithelial-, and neural crest-specific deletion of the Fpr1/2 locus and assessed ENS structure and GI motility.
Therapeutic effects of Panax ginseng polysaccharides on qi deficiency diabetes: Insights from microbiomics and metabolomics.
J Chromatogr B Analyt Technol Biomed Life Sci
August 2025
School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China. Electronic address:
Panax ginseng, a traditional medicinal and edible plant valued for its tonifying properties, exhibits diverse pharmacological activities, including anti-fatigue, anti-oxidation and anti-diabetes. Polysaccharides represent a key active ingredient of Panax ginseng, known for their immunomodulatory properties and potential for development as health foods. However, the effect and mechanism of Panax ginseng polysaccharides (GP) on improving qi deficiency diabetes (QDD) is still unclear.
View Article and Find Full Text PDFTriptolide improves microbial dysbiosis and metabolite disorder in db/db mice.
Ren Fail
December 2025
Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital, Nanjing University of Chinese Medicine, Shenzhen, China.
Background: Diabetic kidney disease (DKD) is an increasing global public health problem. Triptolide (TP) has a good therapeutic effect on DKD and is widely used in China. However, the mechanism of TP is still unclear.
View Article and Find Full Text PDF