Sugar Esters of Fatty Acids: Chemo-Enzymatic Synthesis and Biological Activity.

Molecules

Department of Biotechnology and Food Microbiology, Wrocław University of Environmental and Life Sciences, 51-630 Wrocław, Poland.

Published: July 2025


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Article Abstract

Human applications of surfactants have been diverse, from their initial use as detergents to their subsequent utilization in a multitude of other fields, including medicine, lubricants, cosmetics, and even assisted oil recovery. Nevertheless, the most significant challenge lies in the synthesis of surfactants. A particular challenge is the purification of compounds following chemical synthesis, as well as the toxic effect of the solvents used. Consequently, there is a growing need for more environmentally friendly solutions, namely solvents that are less toxic and more biocompatible, as well as reactions in which an enzyme serves as a catalyst. This review examines the various methods of synthesizing sugar esters and glycolipids, evaluating their respective advantages and disadvantages.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12348620PMC
http://dx.doi.org/10.3390/molecules30153123DOI Listing

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