Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Fe-based single-atom catalysts display extraordinary activity in the Fenton-like reaction, but low Fe atom densities limit their overall catalytic performance. In addition, high-valent iron (as Fe═O) plays a pivotal role due to the selective degradation of contaminants in water. However, it is rarely reported for Fe═O generation in the HO-based Fenton-like process. This study confirmed that the Fe atom (Fe and Fe) and the Fe cluster coexisted in the as-synthesized catalyst, in which the penta-coordinated Fe atom (Fe-N) was found instead of the normal Fe-N. The Fe content reaches 13.7 wt % in the catalyst, which is significantly higher than the normal Fe atom density (less than 5 wt %). The ratio of the Fe atom to the Fe cluster is 89.8% at the surface of the catalyst. Furthermore, Fe═O was generated during the HO-based Fenton-like reaction. The density functional theory and experimental results confirm that the synergistic effect between FeN and the Fe cluster enhanced the catalytic activity and Fe═O formation. The catalyst showed selective degradation for electron-rich contaminants such as tetracycline hydrochloride via the Fenton-like reaction, in which the nonradical pathway by Fe═O dominated the degradation process.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.langmuir.5c02751 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Enzyme-mediated nanoreactors with cascade metabolic modulation for enhanced chemo-chemodynamic combination therapy.
J Colloid Interface Sci
September 2025
School of Materials, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. Electronic address:
Harnessing the significant buildup of lactic acid (LA) within the tumor microenvironment (TME) for metabolic manipulation presents a promising avenue for cancer treatment. Nevertheless, single-agent therapies often fail to address the complex and varying needs of TME heterogeneity, posing a substantial scientific hurdle in oncology. In this context, we employ asymmetric mesoporous silica nanoparticles (AMS NPs) as delivery vehicles, simultaneously loading them with zinc‑cobalt‑manganese ferrite nanoparticles (ZCMF NPs), lactate oxidase (LOX), and doxorubicin (DOX).
View Article and Find Full Text PDFAn injectable hyaluronic acid-based hydrogel for the treatment of breast cancer.
Colloids Surf B Biointerfaces
September 2025
Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Ministry of Education, School of Chemical Engineering, Northwest University, Xi'an 710127, China; Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation
In this study, we develop a hyaluronic-tannic acid (HA-TA) hydrogel loaded with Cu nanoparticles attach to MXene (MXene@Cu) to explore its potential as a targeted breast cancer treatment. The MXene@Cu nanosheets exhibit activity in depleting glutathione (GSH) and inducing reactive oxygen species (ROS) through the Fenton-like reaction. They can down-regulate the activity of glutathione peroxidase 4 (GPX4), leading to the accumulation of lipid peroxides (LPO) and inducing ferroptosis in tumor cells.
View Article and Find Full Text PDFMitoSiege-Driven Catalase Collapse: A GSH-Responsive, Mitochondria-Targeted COF Prodrug for Amplified Chemodynamic Therapy.
Angew Chem Int Ed Engl
September 2025
Department of Chemistry, Korea University, Seoul, 02841, South Korea.
Chemodynamic therapy (CDT), leveraging Fenton reactions to generate hydroxyl radicals (•OH) from intracellular hydrogen peroxide (HO), offers a promising cancer treatment strategy due to its high specificity and low systemic toxicity. However, the targeted delivery of •OH-producing prodrugs using covalent organic frameworks (COFs) remains a significant challenge. Here, we report a mitochondria-targeted COF-based nano prodrug, COF-31@P, designed for enhanced CDT efficacy.
View Article and Find Full Text PDFCu(OH)PO@PAA Nanoparticles for Highly Effective Combination of Chemodynamic, Photodynamic and Photothermal Therapies Against Bladder Cancer.
Int J Nanomedicine
September 2025
Department of Ultrasonic Imaging, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Background: Due to the complex structure and variable microenvironment in the progression of bladder cancer, the efficacy of traditional treatment methods such as surgery and chemotherapy is limited. Tumor residual, recurrence and metastasis are still difficult to treat. The integration of diagnosis and treatment based on nanoparticles can offer the potential for precise tumor localization and real-time therapeutic monitoring.
View Article and Find Full Text PDFElectronic Structure Reconfiguration of Zn-NB Sites for Enhanced Fenton-Like Catalysis.
Angew Chem Int Ed Engl
September 2025
College of Environmental Science and Engineering, Yangzhou University, Yangzhou, 225000, P.R. China.
Despite growing interest in single-atom catalysts (SACs) for Fenton-like reactions, zinc (Zn)-based SACs remain unexplored due to the inherent inertness of Zn, whose fully occupied 3d electronic configuration limits redox activity. Here, we overcome this limitation by introducing boron (B) atoms to reconfigure the electronic structure of Zn-N coordination sites, yielding an activated catalyst denoted as Zn-NBC. This electronic modulation transforms inert Zn-N sites into catalytically active centers (Zn-NB ), enabling significantly enhanced Fenton-like activity.
View Article and Find Full Text PDF