Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Spike morphology is crucial for wheat (Triticum aestivum L.) yield and environmental adaptation. We developed a high-throughput phenotyping platform to dissect spike morphology traits based on 54 traits in 1,359 wheat accessions. These 54 spike morphology traits exhibited clear geographical differences among 306 worldwide accessions and breeding selection trend across different time windows for 1,053 accessions released from 1900 to 2020 in China. Based on geographical distribution and breeding selection of haplotypes, we attribute the differences in spike morphology to variable haplotype combinations. Wheat breeding breaks the trade-off between spike length and width/thickness, resulting in increased spike volume. A large proportion of genomic regions has been identified across wheat varieties and utilized as a fixed group to facilitate the targeted improvement and selection of desirable traits during wheat breeding programs. Overall, we provide a resource for the molecular design of spike morphology to facilitate future wheat breeding.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.celrep.2025.116120 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Reshaping epigenomic landscapes facilitated bread wheat speciation.
Plant Physiol
September 2025
Laboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Polyploidization is a driving force of wheat (Triticum aestivum) evolution and speciation, yet its impact on epigenetic regulation and gene expression remains unclear. Here, we constructed a high-resolution epigenetic landscape across leaves, spikes, and roots of hexaploid wheat and its tetraploid and diploid relatives. Inter-species stably expressed genes exhibited conserved amino acid sequences under strong purifying selection, while dynamically expressed genes were linked to species-specific adaptation.
View Article and Find Full Text PDFSpatial Transcriptomics and Single Cell-RNASeq Reveals Cellular Heterogeneity of SARS-CoV-2 in Lung Tissues and Global Mutational Patterns in COVID-19 Patients.
J Med Virol
September 2025
Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
RNA viruses have high mutation frequency, quick generation periods and vast population numbers, which promote fast evolution and host environment adaptation. We integrated scRNA-seq and spatial transcriptomics to profile immune cells and viral gene expression in COVID-19. Cell types and interactions were identified using Seurat-based tools.
View Article and Find Full Text PDFExploring the genetic variation of wheat- introgression lines for flowering morphology traits for hybrid wheat use.
Front Plant Sci
August 2025
Nottingham Wheat Research Centre, School of Biosciences, University of Nottingham, Loughborough, United Kingdom.
Introduction: The autogamous nature of wheat presents a significant challenge for hybrid wheat breeding, which relies on cross-pollination. To facilitate hybrid wheat production, it is essential to modify the floral morphology of wheat to promote outbreeding rather than inbreeding. While some genetic diversity for flower morphology exists within wheat, it is limited compared to the vast and largely untapped genetic variation found in its wild relatives for potentially all agronomically important traits, including flowering characteristics.
View Article and Find Full Text PDFDevelopment of an in vitro method to assess the immunogenicity of biologics in the prevention of infectious diseases.
Immunol Res
September 2025
Centre for Advanced Materials and Technologies, Warsaw University of Technology, Warsaw, Poland.
We present a series of preclinical studies focused on developing in vitro 2D and 3D models for assessing immunogenic factors in preventing infectious diseases. Human peripheral blood mononuclear cells (PBMC) and Calu-3 cell lines (bronchial epithelial cells) were used to develop 2D and 3D models. Peptides: Spike-S1-His (S-His), nucleocapsid-His and adjuvants: human adenovirus five serotype-based viral vector (AdV-D24-ICOSL-CD40L), armed with inducible co-stimulator (ICOSL) and CD40 ligand (CD40L), and a vector lacking these transgenes (AdV5/3) were used due to their effective initial interaction with antigen-presenting cells (APC).
View Article and Find Full Text PDFA case report of pulmonary sarcoidosis with fibrosis after COVID-19 is presented. Morphologic and immunohistochemical analysis of lung biopsies for Sars-Cov2 nucleocapsid and adhesion proteins was performed. Virus proteins were detected in alveolar macrophages, second-order pneumocytes and bronchiolar epithelium, also in granuloma-associated macrophages, multinucleated Pirogov-Langhans cells, indicating Sars-Cov2 persistence.
View Article and Find Full Text PDF