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http://dx.doi.org/10.1007/s00405-025-09587-3 | DOI Listing |
J Voice
September 2025
Department of Otolaryngology - Head & Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), Paris, France.
Objective: To investigate the potential relationship between retrograde cricopharyngeal dysfunction (R-CPD) and laryngopharyngeal reflux disease (LPRD) at baseline and whether cricopharyngeal sphincter paralysis botulinum toxin injection (BTI) is associated with an increase of LPRD symptoms in treated R-CPD patients.
Methods: Patients with clinical diagnosis of R-CPD were prospectively recruited from two European hospitals. Controls included individuals unable to burp without troublesome symptoms (CT1) and healthy subjects able to burp (CT2).
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2025
Department of Otolaryngology, Peking University Third Hospital, Beijing 100191,China.
To explore the clinical and salivary metabolic component characteristics of patients with OSA combined with LPRD, and to investigate the potential co-morbid mechanisms of LPRD and OSA. A total of 98 adult patients with OSA (81 males and 17 females) who visited the Department of Otolaryngology of Peking University Third Hospital from March 2024 to May 2024 were consecutively included. The age ranged from 19 to 68 years (mean±standard deviation: 39.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2025
Department of Otorhinolaryngology Head and Neck Surgery, the Sixth Medical Center of PLA General Hospital, and National Clinical Research Center for Otolaryngologic Diseases, Beijing 100048, China.
To study the characteristics of laryngopharyngeal reflux (LPR) events in patients with obstructive sleep apnea (OSA). This cross-sectional study analyzed OSA patients who were admitted in the Department of Otolaryngology-Head and Neck Surgery, the Sixth Medical Center of the Chinese PLA General Hospital between November 2020 to July 2023[OSA group, 52 males, 6 females, aged 23-69 (41.22±11.
View Article and Find Full Text PDFJ Voice
August 2025
Department of Surgery, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otolaryngology - Head & Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines
Objective: To review the current literature dedicated to the effectiveness of the diet recommendations for laryngopharyngeal reflux disease (LPRD).
Methods: Two independent investigators conducted a PubMED, Scopus, and Cochrane Library database search for studies investigating the effectiveness of anti-reflux diet in LPRD patients. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements and the Methodological Index for Non-Randomized Studies (MINORS) tool were considered for study analyses.
J Voice
August 2025
Department of Surgery, Research Institute for Language Science and Technology, University of Mons (UMons), Mons, Belgium; Department of Otolaryngology Head Neck Surgery, CHU Saint-Pierre, Brussels, Belgium; Department of Otolaryngology-Head & Neck Surgery, Foch Hospital, School of Medicine, UFR Simo
Objective: To analyze the methods used for digestive enzyme measurements in saliva of patients with laryngopharyngeal reflux disease (LPRD) and to investigate their respective diagnostic performances.
Methods: Three independent investigators conducted a PubMED, Scopus, and Cochrane Library database search for studies investigating the digestive saliva enzyme measurements in LPRD patients according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements.
Results: Of the 183 screened studies, 38 studies met the inclusion criteria (1461 females (47.