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http://dx.doi.org/10.1111/ddg.15842 | DOI Listing |
Acta Obstet Gynecol Scand
September 2025
Unit of Gynecological Oncology, Department of Oncology, KU Leuven, Leuven, Belgium.
Introduction: Vulvovaginal cancer in pregnancy is rare. Limited data complicate decision-making and patient counseling. Our review, coupled with new case data, fills a current gap in the literature and provides practical insights.
View Article and Find Full Text PDFCan Vet J
September 2025
Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn Alabama, USA (Schwartz, Waters, Cole, Forehand, Prim, Rush, Stockler); Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn Alabama, USA (Neto).
A 1-year-old intact Nigerian dwarf nulliparous doe was presented to the Auburn University College of Veterinary Medicine, Large Animal Teaching Hospital in March 2024 for evaluation of recurrent perivulvar masses of 3 mo duration. Transcutaneous ultrasonographic examination of the labia and ventrolateral peri-vulvar area was carried out. This examination revealed a horizontally oriented, bilobed mass on the dorsal left labia majora, and a separate mass located directly below the ventral vulvar commissure.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
This study presents a rare case of primary vulval sebaceous carcinoma (SC) and a literature review. Sebaceous carcinoma is an aggressive skin malignancy, predominantly periocular, with extraocular cases being particularly uncommon. We detail a 50-year-old female patient diagnosed with primary vulval SC, exhibiting a 0.
View Article and Find Full Text PDFCase Rep Dermatol Med
August 2025
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia.
Squamous cell carcinoma (SCC) of the vulva is caused by disturbances in the proliferation and differentiation of the squamous epithelium, which can be associated with human papillomavirus (HPV) infection. Vulvar SCC is usually caused by high-risk HPV types, although there are some cases that are caused by low-risk HPV types. The clinical manifestations of vulvar SCC vary, one of which can resemble anogenital warts.
View Article and Find Full Text PDFInt J Gynaecol Obstet
September 2025
Department of Obstetrics and Gynecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Immune checkpoint inhibitors (ICIs) have transformed cancer treatment by leveraging the immune system's capacity to fight gynecologic cancer. This review summarizes the current status and future perspectives of ICIs in the treatment of cervical, endometrial, and ovarian cancers and rare tumors. ICIs have demonstrated significant efficacy in tumors with high tumor mutational burden and immune markers such as PD-L1 expression and microsatellite instability.
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