Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Introduction: Laryngopharyngeal reflux (LPR) is a common disease in the outpatient department of otolaryngology and is characterised by backflow of stomach contents into the pharynx and larynx resulting in significant negative impact on the quality of life of patients. The aim of study was to assess the effect of proton pump inhibitor (PPI) on quality of life in patients with LPR.
Method: 110 patients diagnosed with LPR were enrolled in study and prescribed omeprazole (20 mg) twice daily for 12 weeks. The Reflux Symptom Index (RSI), Reflux Finding Score (RFS) and LPR-health-related quality of life (HRQOL) were recorded for each patient at the initial visit and at 4th, 8th and 12th week follow-up visits.
Results: Mean RSI, RFS, HRQOL was 15.28 ± 1.19, 12.65 ± 1.16 and 77.77 ± 11.80 respectively at baseline. Significant improvement was observed in RSI and RFS scores after treatment. The HRQOL score also showed gradual improvement after PPI treatment.
Conclusion: PPI treatment brought about a significant improvement in signs, symptoms and quality of life of LPR patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297158 | PMC |
| http://dx.doi.org/10.1007/s12070-025-05621-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Use of Deep Learning in Primary Agricultural Products Freshness Assessment: A Systematic Review.
J Food Sci
September 2025
College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Primary agricultural products are closely related to our daily lives, as they serve not only as raw materials for food processing but also as products directly purchased by consumers. These products face the issue of freshness decline and spoilage during both production and consumption. Freshness degradation induces sensory deterioration and nutritional loss and promotes harmful substance accumulation, causing gastrointestinal issues or even endangering life.
View Article and Find Full Text PDFCross-cultural adaptation, validity and reliability of the Dutch version of the Lymphedema Symptom Intensity and Distress Survey-Head and Neck version 2.0 (LSIDS-H&N v2.0) in head and neck cancer patients.
Disabil Rehabil
September 2025
Department of Rehabilitation Sciences and Physiotherapy, University of Leuven, Leuven, Belgium.
Purpose: This study aims to cross-culturally validate the Dutch version of the Lymphedema Symptom Intensity and Distress Survey-Head and Neck version 2.0 (LSIDS-H&N v2.0).
View Article and Find Full Text PDFA reinvigorated Health and Quality of Life Outcomes: recent successes and renewed aims & scope.
Health Qual Life Outcomes
September 2025
Department of Health Policy, Corvinus University of Budapest, 8 Fővám tér, Budapest, H-1093, Hungary.
Estimating Health State Utilities for IDH-Mutant Diffuse Glioma.
Pharmacoecon Open
September 2025
Acaster Lloyd Consulting Ltd, Lacon House, 84 Theobalds Rd, London, WC1X 8NL, UK.
Background: Isocitrate dehydrogenase-mutant (mIDH) gliomas are malignant central nervous system tumours. After initial resection, patients with mIDH gliomas with favourable prognosis may live without receiving oncologic treatment for years, but ultimately patients will experience recurrence and require radio- and/or chemotherapy (RT/CT). Cost-utility analyses (CUA) can explore the value of treatments that delay recurrence and initiation of RT/CT.
View Article and Find Full Text PDFSocioeconomic differences in the cost-effectiveness of a telephone-based intervention for obesity prevention in early childhood.
Int J Obes (Lond)
September 2025
Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Objectives: This study investigated the cost-effectiveness of an early childhood obesity prevention intervention providing telephone and short message service (SMS) support to mothers of children aged 2-4 years by socioeconomic position (SEP).
Methods: A model-based SEP-specific economic evaluation of the intervention was conducted. SEP-specific intervention costs and effects at age 5 years were derived from the trial data and applied to a cohort of 4- to 5-year-old Australian children.