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Background: In thoracic surgery, the concept of Enhanced Recovery After Surgery (ERAS) has been extensively implemented. Although numerous studies have investigated ERAS in thoracic surgery, bibliometric analyses remain limited. In this study, the developmental trajectory, current research status, and prospective trends of ERAS in thoracic surgery were systematically analyzed through bibliometric and visual analysis techniques.
Methods: Literature pertaining to ERAS in thoracic surgery was retrieved from the Web of Science Core Collection (WoSCC). Microsoft Excel 2019, R software (version 4.1.0), the Bibliometric Online Analysis Platform, VOSviewer (version 1.6.18), and Citespace (version 6.3.R1) were utilized for statistical analysis, bibliometric evaluation, and data visualization.
Results: A total of 617 publications were retrieved over the past decade. The number of publications has generally demonstrated an upward trend from 2015 to 2024. China and Sichuan University ranked as the leading country and institution, respectively, in terms of publication volume. The Journal of Thoracic Disease was identified as the leading journal in both publication count and citation frequency. Henrik Kehlet was recognized as the most prolific and highly co-cited author. Current research hotspots include "video-assisted thoracic surgery," "pain management," and "multicenter clinical trials."
Conclusion: ERAS-related research in thoracic surgery has been increasing steadily, highlighting it as a rapidly evolving and promising field. The ERAS concept plays a critical role in all perioperative phases-preoperative, intraoperative, and postoperative-and requires further in-depth investigation. Many existing ERAS studies in thoracic surgery lack high-quality evidence, underscoring the urgent need for rigorously designed research with robust methodological standards.
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http://dx.doi.org/10.1186/s41065-025-00501-9 | DOI Listing |
Lung Cancer
August 2025
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou, China; Guangzhou Institute of Respiratory Health, Guangzhou, C
Background: Large cell neuroendocrine carcinoma (LCNEC) represents a rare and unique type of lung tumor with an unfavorable prognosis. It is essential to summarize the treatment modalities and prognosis for inoperable stage III and IV LCNEC, explore the role of frontline immunotherapy, and examine the stratification role of the Lung Immune Prognostic Index (LIPI) and its relationship with the tumor microenvironment (TME).
Methods: This study retrospectively analyzed 160 patients with inoperable lung LCNEC (L-LCNEC) admitted to three hospitals from December 2012 to November 2023.
J Surg Res
September 2025
Department of Surgery, Keck School of Medicine of USC, Los Angeles, California. Electronic address:
Introduction: Psychiatric comorbidities are increasingly recognized in patients with thoracic malignancies. We undertook this scoping review to characterize the management of thoracic malignancies in patients with psychiatric illness and uncover any disparities in operative treatment or perioperative outcomes.
Methods: We conducted a scoping review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Int Immunopharmacol
August 2025
Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China; Shanghai Engineering Research Center of Lung Transplantation, Shanghai, China. Electronic address:
Background: Protein lactylation has been implicated in stress-responsive cellular mechanisms, yet its role in lung transplantation-associated ischemia-reperfusion injury (IRI) remains undefined.
Methods: Transcriptomic profiles from GSE145989 were analyzed through differential expression analysis (limma) and weighted gene co-expression network analysis (WGCNA). Integrating the identified genes with lactylation-related signatures uncovered key lactylation-related genes (LRGs) as potential targets.
J Thorac Oncol
September 2025
Department of Thoracic Surgery, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital Zhengzhou, People's Republic of China. Electronic address:
J Thorac Oncol
September 2025
Thoracic Surgery Unit, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy; Tumor Immunology and Immunotherapy Unit, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy. Electronic address: