Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Prostatectomy frequently leads to postoperative urinary incontinence (UI), significantly impairing patients' quality of life. While pelvic floor muscle exercises (PFME) are commonly employed, the efficacy of electrical stimulation (ES) as a non-invasive adjunct remains debated. This systematic review and meta-analysis evaluated the effectiveness of ES combined with PFME versus PFME alone for post-radical prostatectomy UI.

Method: A comprehensive search across PubMed, MEDLINE, EMBASE, Cochrane Library, and ResearchGate identified 10 randomized controlled trials (RCTs) meeting inclusion criteria. Outcomes included 24-hour pad test, International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), quality of life (QOL), and incontinence control rate. Data were analyzed using Review Manager 5.4.1, employing fixed- and random-effects models.

Results: Short-term ES (≤3 months) significantly improved ICIQ-SF scores (MD = - 3.50; 95% CI: - 5.11 to -1.89, p < 0.0001) and doubled incontinence control rates (RR = 2.01; p = 0.01), though no improvement was observed in 24-hour pad test (MD = - 50.07; p = 0.30) or QOL. Conversely, long-term ES (≥6 months) demonstrated marked reductions in urinary leakage via the 24-hour pad test (MD = - 21.64; p = 0.02), but no significant differences in ICIQ-SF scores or control rates compared to PFME alone.

Conclusion: Electrical stimulation therapy can be an effective treatment option for patients with post-RP UI. It can significantly improve UI symptoms in the short term and has a positive impact on reducing urinary leakage in the long term.

Download full-text PDF

Source
http://dx.doi.org/10.1097/JS9.0000000000002685DOI Listing

Publication Analysis

Top Keywords

electrical stimulation
12
24-hour pad
12
pad test
12
urinary incontinence
8
systematic review
8
quality life
8
incontinence control
8
iciq-sf scores
8
control rates
8
urinary leakage
8

Similar Publications

Lithobates palmipes is a frog species whose skin secretions contain peptides belonging to the ranatuerin, brevinin, and temporin families. In this study, the peptide ranatuerin-2PMe was isolated and evaluated for its antimicrobial, hemolytic, antiproliferative, and chemotactic activities. Ranatuerin-2PMe (2933.

View Article and Find Full Text PDF

Crossmodal correspondences - systematic mappings between stimulus attributes in different modalities - are ubiquitous in the general population. For example, high-pitched (vs low-pitched) sounds are commonly associated with elevated (vs low) positions in space, and rounded (vs angular) shapes tend to be linked to the term 'Bouba' (vs 'Kiki'). There is still some debate about the role of immediate sensory experience versus conceptual colour understanding in crossmodal correspondences.

View Article and Find Full Text PDF

Reactive astrogliosis and microgliosis in animal models of focally induced seizures: A systematic review and multivariate multilevel meta-analysis.

Epilepsy Behav

September 2025

Institute of Pharmacology and Toxicology, School of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany; Einstein Center for Neurosciences (ECN), Charité - Universitätsmedizin Berlin, Germany. Electronic address:

Reactive astrogliosis and microgliosis are hallmarks of various central nervous system (CNS) diseases, including epilepsy. Both are observed following seizures in various models of epilepsy. We conducted a systematic meta-analysis to synthesize current knowledge on reactive astrogliosis and microgliosis in animal models involving experimentally induced seizures using a multilevel approach to analyze 260 comparisons from 52 studies.

View Article and Find Full Text PDF

Electroacupuncture alleviates intestinal ischemia-reperfusion-induced acute lung injury via the vagus-sympathetic nerve pathway.

Int Immunopharmacol

September 2025

Key Laboratory of Anesthesia and Intensive Care Research, Harbin, China; Department of Anesthesiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address:

Aims: Intestinal ischemia-reperfusion (II/R) injury predominantly causes acute lung injury (ALI), and in severe instances, acute respiratory distress syndrome, both associated with high mortality. Electroacupuncture (EA) excels in regulating autonomic nervous system balance and safeguarding organ function. This study delved into EA's impacts and mechanisms on II/R-induced ALI.

View Article and Find Full Text PDF

Background: Awake surgery is the reference for diffuse low-grade glioma resection, allowing maximal tumor removal while preserving neurocognitive functions. It is also applicable to other brain tumors. However, key technical elements must be followed to ensure optimal conditions for intraoperative cognitive testing and reliable functional mapping.

View Article and Find Full Text PDF