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The management of groin recurrences in women with vulval cancer presents a significant therapeutic challenge. Groin recurrences, particularly those involving the femoral vessels, are associated with poor outcomes. Historically, surgery was often not offered in such cases, exposing patients to the risk of fatal complications from femoral vessel blow-out, leading to exsanguination. This report describes the management of a right large vulval groin recurrence involving the femoral vein, treated successfully with femoral vein ligation. The patient's postoperative recovery was largely uneventful. This case highlights the feasibility of femoral vein ligation when performed with early involvement of vascular surgeons and a multidisciplinary team approach. Femoral vein ligation should be considered in cases of vessel invasion as it can be both life-saving and limb-sparing. Additionally, the report discusses the development of collateral venous circulation, which often compensates for femoral vein obstruction.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180957 | PMC |
http://dx.doi.org/10.1016/j.crwh.2025.e00723 | DOI Listing |
Rheumatology (Oxford)
September 2025
Department of Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey.
Objectives: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder often complicated by vascular events, with or without antiphospholipid antibody syndrome (APS). This study aimed to explore subclinical venous involvement in SLE using biochemical and imaging modalities, focusing on vein wall thickness (VWT) and inflammation-related biomarkers.
Methods: In this cross-sectional study, 68 SLE patients were categorized based on antiphospholipid antibody (APA) status and clinical APS.
Braz J Med Biol Res
September 2025
Departamento de Biofísica e Fisiologia, Universidade Federal do Piauí, Teresina, PI, Brasil.
This study aimed to evaluate the effects of the ketamine-xylazine (KX) anesthetic mixture on autonomic and cardiovascular functions in normotensive rats (Wistar) and spontaneously hypertensive rats (SHR), using both spectral and symbolic analyses. Male Wistar (n=22) and SHR (n=28) rats were intramuscularly anesthetized with KX, and their femoral artery and vein were cannulated for pulsatile arterial pressure recording and drug administration. Autonomic function was assessed 24 and 48 h post-surgery through spectral and symbolic analyses of heart rate (HR) and systolic arterial pressure (SAP) variability.
View Article and Find Full Text PDFJ Neurotrauma
September 2025
The Max Harry Weil Institute for Critical Care Research and Innovation, University of Michigan, Ann Arbor, Michigan, USA.
Cerebrovascular autoregulation (CA) is a protective mechanism against brain injury. We present an ultrasound-based volumetric blood flow indices to monitor CA. Swine were instrumented under general anesthesia to monitor mean arterial blood pressure (MAP), intracranial pressure (ICP), and blood flow in the internal carotid artery (ICA) and femoral artery (FA) and flow velocity and volumetric flow in the middle cerebral artery (MCA) using transcranial Doppler.
View Article and Find Full Text PDFSurg Radiol Anat
September 2025
Department of Mathematics, Manipal Institute of Technology, Manipal Academy of Higher Education, Madhav Nagar, Manipal, Karnataka State, 576104, India.
Front Surg
August 2025
Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Epithelioid hemangioendothelioma (EHE) is a rare and locally aggressive tumour of vascular endothelial origin, with an estimated prevalence of less than 1 in a million. EHE can arise in any part of the body, most commonly in the liver, lungs, and skeleton, while occurrence in the blood vessels of the extremities is rare. This article reports a rare case of primary epithelioid hemangioendothelioma (EHE) of the right femoral artery.
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