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The Global Flourishing Study is a longitudinal panel study of over 200,000 participants in 22 geographically and culturally diverse countries, spanning all six populated continents, with nationally representative sampling and intended annual survey data collection for 5 years to assess numerous aspects of flourishing and its possible determinants. The study is intended to expand our knowledge of the distribution and determinants of flourishing around the world. Relations between a composite flourishing index and numerous demographic characteristics are reported. Participants were also surveyed about their childhood experiences, which were analyzed to determine their associations with subsequent adult flourishing. Analyses are presented both across and within countries, and discussion is given as to how the demographic and childhood relationships vary by country and which patterns appear to be universal versus culturally specific. Brief comment is also given on the results of a whole series of papers in the Global Flourishing Study Special Collection, employing similar analyses, but with more-specific aspects of well-being. The Global Flourishing Study expands our knowledge of the distribution and determinants of well-being and provides foundational knowledge for the promotion of societal flourishing.
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http://dx.doi.org/10.1038/s44220-025-00423-5 | DOI Listing |
HIV Med
September 2025
Department of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Introduction: Human immunodeficiency virus (HIV) remains a significant global health problem, and the number of new cases is increasing in Central Asia, including Kazakhstan. This study aimed to examine the association of a range of demographic, physical health and psychosocial factors with the mental health of people living with HIV in Kazakhstan, applying the two-continua model of mental health, which holds that mental wellbeing and mental illness are two distinct continua that are interrelated in their contributions to overall mental health. The study findings can inform future interventions aimed to prevent mental illness and promote the mental wellbeing of people living with HIV.
View Article and Find Full Text PDFLancet
August 2025
Department of Anesthesia, St Michael's Hospital-Unity Health Toronto, Toronto, ON, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada; Department of Physiology, Univ
Background: Saphenous vein graft (SVG) failure remains a substantial challenge after coronary artery bypass graft (CABG). LDL cholesterol (LDL-C) is a causal risk factor for atherosclerosis, but its role in SVG failure is not well established. We evaluated whether early initiation of intensive LDL-C lowering with evolocumab could reduce SVG failure.
View Article and Find Full Text PDFBMC Glob Public Health
September 2025
Baylor University, Institute for Studies of Religion, Waco, TX, USA.
Background: Health limitations, defined as problems in life that limit an individual from activities of daily living, have been associated with human flourishing, globally. However, how health problems leading to functional limitations vary across multiple demographic characteristics and how these vary across countries requires additional exploration.
Methods: The Global Flourishing Study is a 5-year longitudinal study of human flourishing among 202,898 individuals across 22 countries.
Children (Basel)
August 2025
Curtin School of Population Health, Curtin University, Perth, WA 6102, Australia.
Adverse early childhood developmental outcomes across physical, cognitive, language, communication, and socioemotional domains are major global health concerns. This systematic review aimed to synthesise perinatal and childhood risk factors using a socioecological model. We searched six databases for cohort, case-control, and cross-sectional studies published between January 2000 and January 2024.
View Article and Find Full Text PDFFront Psychol
August 2025
College of Education, University of the Philippines Diliman, Quezon City, Philippines.
Background: Disruptions in education caused by natural disasters, conflict, or global crises pose significant challenges for educators, particularly in physical education (PE), where embodied learning and social interaction are essential. Following the COVID-19 pandemic, supporting the wellbeing of both students and teachers became a central focus of educational recovery. While the PERMAH model of wellbeing has garnered international attention, this study contributes to the growing body of work by exploring how it may take shape within culturally specific and resource-constrained educational contexts.
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