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Background: Many studies have identified the negative psychological impact of in vitro fertilisation and embryo transfer (IVF-ET) on couples with infertility, but there remains a paucity of research clarifying both positive and negative effects within the context of Chinese culture.
Aim: To explore the dynamic psychosocial experiences and underlying mechanisms of couples in the whole process of IVF-ET, and to construct a theoretical framework that elucidates this phenomenon within the context of Chinese social-culture.
Design: A grounded theory study.
Methods: Guided by constructivist grounded theory methodology, semi-structured face-to-face interviews were conducted in the reproductive medicine outpatient department of a tertiary-level hospital located in northwest China between January and October 2023. Purposive and theoretical sampling methods were used to recruit couples undergoing IVF-ET. Data were analysed through three iterative steps: initial coding, focused coding, and theoretical coding, utilising constant comparative methods and reflective memo-writing. The study is reported using the COREQ checklist.
Results: Theoretical saturation was achieved after interviewing 22 couples. The substantive theory was synthesised into one core category: 'forward or backward', which captured the ambivalent psychosocial experiences of couples undergoing IVF-ET within the context of Chinese culture. This theory described three overarching stages: making the decision, undergoing the treatment, and facing the result, with each stage linked to specific promoting and hindering factors.
Conclusion: This study establishes a theoretical foundation for further implementation of comprehensive reproductive health management within the Chinese sociocultural context. It is crucial for healthcare providers and policymakers to focus on the dyad of couples undergoing IVF-ET, pay attention to both negatively and positively psychosocial fluctuations, and enhance both medical care and sociocultural support systems accordingly.
Patient Or Public Contribution: No patient or public contribution.
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http://dx.doi.org/10.1111/jocn.17848 | DOI Listing |
Phys Rev Lett
August 2025
RIKEN, Center for Quantum Computing, Wakoshi, Saitama 351-0198, Japan.
Disorder and non-Hermitian effects together can upend how waves localize. In a 1D disordered chain, the non-Hermitian skin effect (NHSE) can induce Anderson delocalization, defying the usual rule that disorder in low dimensions always localizes states. While weak disorder leaves the NHSE intact, strong disorder restores Anderson localization.
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September 2025
Michael DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada; David Braley Center for Antibiotic Discovery, McMaster University, Hamilton, ON L8S 4K
Many Gram-negative bacteria use type VI secretion systems (T6SSs) to deliver toxic effector proteins into neighboring cells. Proteins in the VasX toxin family form ion-permeable channels in the bacterial cytoplasmic membrane that dissipate the proton motive force, thereby interfering with essential physiological processes. However, the structure of any VasX family effector has remained unknown.
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September 2025
Hainan Institute of East China Normal University, State Key Laboratory of Petroleum Molecular & Process Engineering, Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 20006
A novel sulfinamide reagent was developed that enables the one-step installation of sulfinamides through palladium-catalyzed coupling with aryl iodides. This method offers distinct advantages, including the use of readily available starting materials and broad substrate compatibility. Moreover, the strategy was successfully extended to the synthesis of complex functional molecules.
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August 2025
Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Background And Objective: Parental chromosomal structural variations (SVs) represent a primary genetic factor contributing to recurrent spontaneous abortion (RSA). Individuals carrying SVs with complex chromosomal rearrangements (CCRs) typically exhibit a normal phenotype but are at an increased risk of miscarriage. Current standard clinical detection methods are insufficient for the identification and interpretation of all SV types, particularly complex and occult SVs, thereby presenting a significant challenge for clinical genetic counseling.
View Article and Find Full Text PDFInorg Chem
September 2025
Yunnan Key Laboratory of Crystalline Porous Organic Functional Materials, College of Chemical and Materials Engineering, Qujing Normal University, Qujing 655011, China.
Sequential assembly of donor-acceptor components at the molecular level within a MOF is an effective strategy to achieve efficient electron-hole separation for enhancing the activity of photocatalysts. Meanwhile, the highly efficient and selective functionalization of tetrahydroisoquinoline (THIQ) under mild conditions remains an urgent demand in both the scientific and industrial communities. This work reports a donor-acceptor MOF photocatalyst () constructed by the coordinated assembly of donor and acceptor components, in which a naphthalene unit serves as an electron donor and a perylenediimide unit as an electron acceptor.
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