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This study proposes a novel framework based on an entropy-informed graph neural network (EIGNN) integrated with Gaussian distribution (GD) to assess the driving risk of intelligent vehicles in typical traffic scenarios. Existing research often overlooks comprehensive spatiotemporal modeling of vehicle interaction characteristics and the quantification of uncertainty in dynamic risk assessments. In this work, vehicle speed and acceleration are probabilistically modeled using GD, while entropy theory is introduced to quantify risk uncertainty. A risk assessment model based on graph neural networks (GNNs) is then designed to capture the spatiotemporal dynamics of multivehicle interactions and predict the potential risk levels of driving strategies. The results demonstrate that the framework accurately quantifies collision risks in multivehicle interactions in complex traffic scenarios, with high accuracy and robustness across typical situations such as cruising, cut-ins, lane changes, overtaking, and different density traffic. By thoroughly analyzing traffic risk characteristics and incorporating them into intelligent driving decision-making, this study provides significant technical insights and theoretical support for enhancing the safety and decision-making efficiency of autonomous driving systems.
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http://dx.doi.org/10.1109/TNNLS.2025.3569826 | DOI Listing |
J Org Chem
September 2025
State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin 124221, P. R. China.
The Buchwald-Hartwig (B-H) reaction graph, a novel graph for deep learning models, is designed to simulate the interactions among multiple chemical components in the B-H reaction by representing each reactant as an individual node within a custom-designed reaction graph, thereby capturing both single-molecule and intermolecular relationship features. Trained on a high-throughput B-H reaction data set, B-H Reaction Graph Neural Network (BH-RGNN) achieves near-state-of-the-art performance with an score of 0.971 while maintaining low computational costs.
View Article and Find Full Text PDFMol Omics
September 2025
Laboratory of Structural Bioinformatics and Computational Biology, Federal University of Rio Grande do Sul, Av. Bento Gonçalves, 9500, Porto Alegre 91501-970, RS, Brazil.
The integration of multimodal single-cell omics data is a state-of-art strategy for deciphering cellular heterogeneity and gene regulatory mechanisms. Recent advances in single-cell technologies have enabled the comprehensive characterization of cellular states and their interactions. However, integrating these high-dimensional and heterogeneous datasets poses significant computational challenges, including batch effects, sparsity, and modality alignment.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
September 2025
Accurate vascular segmentation is essential for coronary visualization and the diagnosis of coronary heart disease. This task involves the extraction of sparse tree-like vascular branches from volumetric space. However, existing methods have faced significant challenges due to discontinuous vascular segmentation and missing endpoints.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
September 2025
The tumor microenvironment is a dynamic eco system where cellular interactions drive cancer progression. However, inferring cell-cell communication from non-spatial scRNA-seq data remains challenging due to incomplete li gand-receptor databases and noisy cell type annotations. H ere, we propose scGraphDap, a graph neural network frame work that integrates functional state pseudo-labels and graph structure learning to improve both cell type annotation an d CCC inference.
View Article and Find Full Text PDFJ Chem Inf Model
September 2025
Songshan Lake Materials Laboratory, Dongguan 523808, PR China.
Large language models (LLMs) have demonstrated transformative potential for materials discovery in condensed matter systems, but their full utility requires both broader application scenarios and integration with ab initio crystal structure prediction (CSP), density functional theory (DFT) methods and domain knowledge to benefit future inverse material design. Here, we develop an integrated computational framework combining language model-guided materials screening with genetic algorithm (GA) and graph neural network (GNN)-based CSP methods to predict new photovoltaic material. This LLM + CSP + DFT approach successfully identifies a previously overlooked oxide material with unexpected photovoltaic potential.
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