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This short communication examines the complex relationship between China's intensifying social involution and rising mental disorders among youth. We analyze the multidimensional diagnostic challenges specific to this cultural context and propose evidence-based intervention pathways. Key findings highlight the necessity of culturally-sensitive diagnostic approaches that account for China's unique socioeconomic pressures, the manifestation of "involution anxiety" as a culturally-bound syndrome, and the effectiveness of integrated intervention frameworks combining traditional Chinese approaches with contemporary psychotherapeutic techniques. This work contributes to the growing body of transcultural psychiatry literature and provides practical guidance for mental health professionals working with Chinese youth populations.
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http://dx.doi.org/10.1016/j.ajp.2025.104531 | DOI Listing |
Psychogeriatrics
September 2025
Shanghai University of Medicine and Health Sciences, School of Nursing and Health Management, Shanghai, China.
Background: Cognitive frailty (CF), characterised by the co-occurrence of physical frailty and mild cognitive impairment, poses significant risks for adverse health outcomes in community-dwelling older adults, yet effective prediction tools remain limited.
Objective: This study aimed to develop and validate a nomogram model for predicting CF risk in community-dwelling older adults based on multidimensional mental and physical functional markers.
Methods: A cross-sectional analysis included 481 participants (mean age 69.
Medicine (Baltimore)
September 2025
Nanchang Bright Eye Hospital, Nanchang, Jiangxi, China.
Introduction: This bibliometric analysis aims to explore global trends, research hotspots, and future directions in multidrug resistance of multiple myeloma (MM), providing insights for overcoming resistance mechanisms and optimizing therapeutic strategies.
Methods: We analyzed 3300 publications indexed in the Web of Science Core Collection (2015-2024) using CiteSpace and VOSviewer. Multidimensional evaluations of countries/regions, institutions, authors, journals, and keywords were conducted, supplemented by visual network mapping to elucidate research dynamics and collaborative patterns.
Semin Vasc Surg
September 2025
Division of Vascular and Endovascular Surgery, Department of Surgery, Northwell Health, Manhasset, NY; Zucker School of Medicine at Hofstra, Hempstead, NY. Electronic address:
Peripheral arterial disease (PAD) is a prevalent and debilitating condition in elderly patients, often leading to critical limb threatening ischemia (CLTI) and major amputations. While endovascular interventions are usually preferred for their lower perioperative risk, open surgical revascularization should also be considered due to its durability and superior patency in complex disease patterns. Age alone does not determine suitability for surgery; rather, candidacy hinges on frailty, functional status, comorbidities, and anatomical considerations.
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August 2025
Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Recent advances in artificial intelligence (AI) are reshaping the diagnostic and therapeutic of primary aldosteronism (PA). For screening, machine learning models integrate multidimensional data to improve the efficiency of PA detection, facilitating large-scale population screening. For diagnosis, AI-driven algorithms have further enhanced the specificity of PA identification.
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August 2025
School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Background: Ischemic stroke (IS), the leading stroke subtype (∼87%), arises from vascular occlusions, triggering brain necrosis through ischemia-reperfusion injury. Ferroptosis, an iron-driven cell death via Fe-mediated lipid peroxidation, is implicated in IS pathology. This study demonstrates that enoyl-coA hydrolase 1 (ECH1) may serve as a peripheral biomarker and therapeutic target for IS based on ferroptosis signaling.
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