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Magnesium (Mg) alloys have gained much attention for biomedical applications, due to their attractive properties, such as high specific strength, low density, low elasticity modulus, high damping capacity, biodegradation, and relatively good cytocompatibility. However, the biomedical use of Mg alloys also faces several challenges, primarily due to their low corrosion resistance and insufficient strength. Therefore, improving the strength and corrosion resistance of biomedical Mg alloys has become a critical issue. This review briefly summarizes the selection of appropriate alloying elements for biomedical Mg alloys, which is the fundamental factor in determining their microstructure, cytocompatibility, mechanical properties, and corrosion performance. It also discusses typical thermomechanical processing methods, including hot extrusion, hot rolling and hot forging, and examines the influence of deformation mode on microstructure, mechanical properties, and degradation behavior. Specifically, combining different thermomechanical processing methods could be an optimal choice, as it leverages the high efficiency and effectiveness of each method. Finally, the clinical application of biomedical Mg alloys in various fields are summarized and discussed to highlight their potential prospect and corresponding challenges. This review aims to provide insights for the rationale design and development of high-performance biomedical Mg alloys for widespread clinical applications.
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http://dx.doi.org/10.3390/ma18081718 | DOI Listing |
Small
September 2025
Institute of Thin Film Physics and Applications, Shenzhen Key Laboratory of Advanced Thin Films and Applications, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, State Key Laboratory of Radio Frequency Heterogeneous Integration, College of Physic
Antimony selenide (SbSe), a narrow-bandgap semiconductor with strong light absorption, exhibits photoresponse up to ≈1050 nm due to its intrinsic 1.15 eV bandgap. To extend detection into the near-infrared (NIR, 700-1350 nm), Bi-alloyed (BiSb)Se is developed via vacuum sputtering and postselenization.
View Article and Find Full Text PDFPLoS One
September 2025
Mechanical and Nuclear Engineering Department, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Sectionally nonlinearly functionally graded (SNFG) structures with triply periodic minimal surface (TPMS) are considered ideal for bone implants because they closely replicate the hierarchical, anisotropic, and porous architecture of natural bone. The smooth gradient in material distribution allows for optimal load transfer, reduced stress shielding, and enhanced bone ingrowth, while TPMS provides high mechanical strength-to-weight ratio and interconnected porosity for vascularization and tissue integration. Wherein, The SNFG structure contains sections with thickness that varies nonlinearly along their length in different patterns.
View Article and Find Full Text PDFACS Omega
September 2025
Department of Physics, Federal University of Sergipe, 49100-000 São Cristovão, SE, Brazil.
Hybrid coatings composed of crystalline monetite (CaHPO) and kefir-derived Dextran were synthesized on Ti6Al4V substrates using a low-temperature sol-gel-assisted route (≤80 °C), enabling biopolymer integration without thermal degradation. X-ray diffraction (XRD) confirmed the formation of triclinic monetite nanocrystals (∼152 nm), while Fourier transform infrared (FTIR) and scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS) analyses verified the uniform incorporation of Dextran, particularly in the 4 wt % formulation, which yielded compact, homogeneous surfaces. Electrochemical evaluations in Fusayama artificial saliva revealed a substantial enhancement in corrosion resistance, with the open-circuit potential shifting from -0.
View Article and Find Full Text PDFSmall Methods
September 2025
Research Center for Analysis and Measurement, Faculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, P. R. China.
Platinum and non-precious metal (PtM) alloy multimetallic catalysts have been developed to address the kinetically sluggish oxygen reduction reaction (ORR) occurring at the cathodes of proton exchange membrane fuel cells (PEMFCs). However, these catalysts inevitably suffer from poor lot-to-lot consistency of chemical compositions and structures during production, and the transition metal leaching in practical applications. Thus, the development of high-performance monometallic Pt catalysts using innovative nanoarchitectures has become important to address the technical challenges that hinder the widespread deployment of the PEMFCs.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Department of Pediatric Dentistry (Department of Preventive Dentistry), School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, No.44-1 Wenhua Road West, 250012 Jinan, Shandong, China.
Guided bone regeneration (GBR) is a prominent focus in biomedical materials research, yet few studies address practical clinical needs. GBR membranes must fulfill the "PASS" principles to be effective in surgery, but existing membranes often fall short in balancing antibacterial activity, controlled degradation, osteoinductive potential, and mechanical support. In this study, we employed laser powder bed fusion (LPBF) to fabricate a porous WE43 magnesium alloy scaffold suitable for large alveolar bone defects.
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