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Understanding the formation and interactions of out-of-phase cavitation bubbles is crucial for comprehensively exploring cavitation processes in both nature and engineering applications. In this study, a numerical model for the interaction of out-of-phase cavitation bubbles is developed using the hybrid thermal lattice Boltzmann method, where cavitation bubbles are solely excited by thermal nucleation. Furthermore, a new temperature distribution function for thermal nucleation is proposed, enabling a more stable generation of cavitation bubbles. By comparing the results with those obtained from the Rayleigh-Plesset equation incorporating the thermal effect term, the validity of the thermal nucleation model has been verified. Subsequently, the validity of two out-of-phase cavitation bubbles model is experimentally verified, and the dynamic and thermodynamic behaviors of two out-of-phase cavitation bubbles are systematically investigated. The behaviors are primarily influenced by the dimensionless bubble spacing l and the dimensionless phase difference Δθ. Specifically, when l≥1.00, weak interaction is observed, and no penetration phenomenon occurs. When l<1.00 and Δθ<0.50, strong interaction is observed, and a penetration phenomenon occurs. Finally, the jet-enhancement effect of two out-of-phase cavitation bubbles is explored. The results indicate that when l=0.78, the optimal jet-enhancement effect can be achieved by maintaining Δθ=0.67. These findings provide important numerical insights for optimizing jet-enhancement in cavitation-related technologies.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124725 | PMC |
http://dx.doi.org/10.1016/j.ultsonch.2025.107365 | DOI Listing |
Ultrason Sonochem
August 2025
Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Service Hospitalier Frédéric Joliot, Orsay 91401, France. Electronic address:
Microbubble-mediated focused ultrasound is a promising strategy for transient and localized blood-brain barrier (BBB) permeabilization, enabling drug delivery to the brain. Optimizing microbubble stability and acoustic response is essential to maximize treatment efficiency and minimize potential damage. This study introduces an innovative microbubble formulation with a phospholipid-fluoropolymer shell (LIP-POL), designed to enhance circulation persistence while maintaining a low cavitation threshold.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109-5667, United States.
Phase-shift droplets undergoing acoustic droplet vaporization (ADV) offer a promising approach for ultrasound-mediated drug delivery, enabling the spatiotemporally controlled release of therapeutic payloads. A comprehensive understanding of their behavior, through both optical and acoustic methods, is essential for optimizing the therapeutic efficacy. In this study, we investigated the effects of driving pressure, pulse duration, and bulk boiling point of perfluorocarbon droplets on ADV dynamics, payload release, and acoustic emissions.
View Article and Find Full Text PDFUltrason Sonochem
August 2025
School of Materials Science and Engineering, Xi'an University of Technology, Xi' an 710048 Shaanxi, China.
Cavitation erosion could lead to material loss and structural damage in the flow components of hydraulic machinery, affecting the stable operation and efficiency of the equipment. This study established a cavitation erosion distance model for the gap in the cavitation field. High-speed cameras were used to capture the bubble distribution under different cavitation erosion distances.
View Article and Find Full Text PDFUltrason Sonochem
August 2025
Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Postdoctoral Workstation of Chongqing General Hospital, Chongqing, China; Department of Ultrasound, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Chi
Ultrasonic cavitation in viscoelastic media is a physical process that features in a variety of chemical reactions, food processing, and biomedical applications due to a range of cavitation-associated physical, chemical, and biological effects. The cavitation effects are essentially caused by the dynamic behaviors of oscillating bubbles, which are strongly influenced by the complex and various inter-bubble interactions. However, how cavitation bubbles interact with each other and these interactions subsequently influence the ultrasonic cavitation dynamics and acoustic emissions in viscoelastic materials still remain poorly understood.
View Article and Find Full Text PDFUltrason Sonochem
August 2025
Donghai Laboratory, Zhoushan 316021, China; Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, China. Electronic address:
Hydrodynamic cavitation offers a promising technological platform for diverse industrial applications, including water treatment and chemical process intensification, and holds significant potential for widespread adoption in future advanced processing systems. This study investigates the disinfection efficacy of a novel Cylindrical Rotational Hydrodynamic Cavitation Reactor (CRHCR) and elucidates the underlying mechanism of Escherichia coli (E. coli) inactivation induced by hydrodynamic cavitation.
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