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Article Abstract

In this work we show how a network inspired by a coarse-grained description of actomyosin cytoskeleton can learn - in a contrastive learning framework - from environmental perturbations if it is endowed with mechanosensitive proteins and motors. Our work is a proof of principle for how force-sensitive proteins and molecular motors can form the basis of a general strategy to learn in biological systems. Our work identifies a minimal biologically plausible learning mechanism and also explores its implications for commonly occuring phenomenolgy such as adaptation and homeostatis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045384PMC

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