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http://dx.doi.org/10.1186/s12943-025-02303-z | DOI Listing |
Hum Genomics
August 2025
Department of Hepatobiliary Pancreatic Surgery, Medical School, South China Hospital, Shenzhen University, Shenzhen, 518116, People's Republic of China.
Background: The causal relationship between Transient receptor potential (TRP) and hepatocellular carcinoma (HCC) remains unclear. Our study aimed to identify potential drug targets for HCC within the TRP family using Mendelian randomization (MR).
Methods: The gene expression quantitative trait loci (eQTL) data for TRP was sourced from eQTLGen Consortium.
Sci Rep
July 2025
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Int J Biol Sci
June 2025
Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine - Hangzhou, China.
[This corrects the article DOI: 10.7150/ijbs.86227.
View Article and Find Full Text PDFTheranostics
June 2025
Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
[This corrects the article DOI: 10.7150/thno.34327.
View Article and Find Full Text PDFTransl Pediatr
May 2025
Department of Gland Surgery, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Background: Osteosarcoma (OS), the most common pediatric bone tumor, faces challenges with frequent relapse despite treatment advances. Identifying early diagnostic biomarkers and therapeutic targets is critical. The purpose of this study was to investigate the novel biomarkers for OS, and we also aimed to explore whether these biomarkers could potentially serve as the therapy targets.
View Article and Find Full Text PDF