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Ganoderma polysaccharides (GPs), derived from various species of the Ganoderma genus, exhibit diverse bioactivities, including immune modulation, anti-tumor effects, and gut microbiota regulation. These properties position GPs as dual-purpose agents for medicinal and functional food development. This review comprehensively explores the structural complexity of six key GPs and their specific mechanisms of action, such as TLR signaling in immune modulation, apoptosis pathways in anti-tumor activity, and their prebiotic effects on gut microbiota. Additionally, the structure-activity relationships (SARs) of GPs are highlighted to elucidate their biological efficacy. Advances in green extraction techniques, including ultrasonic-assisted and enzymatic methods, are discussed for their roles in enhancing yield and aligning with sustainable production principles. Furthermore, the review addresses biotechnological innovations in polysaccharide biosynthesis, improving production efficiency and making large-scale production feasible. These insights, combined with ongoing research into their bioactivity, provide a solid foundation for developing health-promoting functional food products that incorporate GPs. Furthermore, future research directions are suggested to optimize biosynthesis pathways and fully harness the health benefits of these polysaccharides.
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http://dx.doi.org/10.1007/s13659-025-00496-w | DOI Listing |
Pestic Biochem Physiol
November 2025
Anhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, School of Resource & Environment, Anhui Agricultural University, Hefei, Anhui 230036, China; Institute of Ecological Environmental Protection and Pollution Remediation Engineering, Anhui Agricultural U
Neonicotinoid insecticides residuals pose a threat to aquatic ecosystems and human health. Imidaclothiz, as a novel neonicotinoid pesticide, the metabolic mechanisms in aquatic environments was unclear. This study investigated the degradation characteristics of imidaclothiz in both pure and actual water, and analyzed the photodegradation and hydrolysis metabolites of imidaclothiz in aquatic environments and assessed their toxicity.
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November 2025
Key Laboratory of Agri-Food Safety of Anhui Province, Anhui Agricultural University, Hefei 230036, China. Electronic address:
The Asian Corn Borer (ACB), Ostrinia furnacalis (Guenée) is a devastating pest of maize, causing significant yield and economic losses in Asia. GABA receptor inhibitors have served as effective tools for controlling ACB larvae over the past several decades. However, the toxicity levels and pharmacological properties of two insecticides, fluxametamide and fipronil against the ACB are still unclear.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China. Electronic address:
Azadirachtin, a highly effective botanical pesticide, demonstrated notable biological activities against Spodoptera frugiperda, including mortality induction, growth and development inhibition, and antifeedant effects. Neuropeptide F (NPF) has been shown to play a role in various physiological processes in insects. Nonetheless, the functions of Sf-NPF1 in regulating food intake and antifeedant induction by azadirachtin in S.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Jiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang, 330013, PR China; Department of Ecology and Environment, Yuzhang Normal University, Nanchang, 330103, PR China. Electronic address: pushouzhi
Background: The hydrogen sulfide (HS) in spoilage of raw meat poses significant food safety risks to human health. Meanwhile, as a signaling molecule, HS is crucial for maintaining human physiological homeostasis. Thus, the establishment of an efficient method for HS detection is essential for safeguarding human health.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Measurement Technology & Instrumentation Key Laboratory of Hebei Province, Institute of Electrical Engineering, Yanshan University, Qinhuangdao, 066004, China.
Background: With the development of modern agriculture, neonicotinoid pesticides have been widely used due to their high efficiency and strong systemic properties. However, excessive use leads to the accumulation of residues in the food chain, threatening the ecosystem and human health. Pesticide residues are easily accumulated in oilseed crops and become concentrated during the edible oil refining process.
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