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Objective: To determine if the PinkWave (PW) light-curing unit (LCU) that emits red and infrared (IR) light as well as violet and blue light improves the depth of cure and degree of conversion (DC) of resin-based composites (RBCs).
Methods: The DC of RBCs at various distances was calculated from data collected at a rate of 13 Hz using attenuated total reflectance Fourier-transform infrared spectroscopy. To assess the contributions of the different wavelengths of light, optical filters were used to block the red and IR light from the PW. The depth of cure was also evaluated by photocuring RBC samples in both metal and plastic molds for 20 s at a 0 mm distance. The length of resin remaining was then measured and divided by 2. Starting from a baseline of 32 °C, the temperature rise during photocuring was measured in the plastic and metal rings reproducing the conditions used to measure the depth of cure and the DC respectively.
Results: In general, the PW produced greater depth of cure, however the use of metal molds greatly reduced this effect because the temperature increase was reduced. Increasing the distance by up to 4 mm from the light tip produced a significant increase in the DC for the RBCs photocured with the PW, but not for the G4. The wavelength of the blue peak (peaking at 473 nm) from the PW was longer compared to the control LCU (peaking at 448 nm). This 25 nm difference negatively affected the photocuring efficiency of some resins.
Significance: The internal optics and the additional red and IR wavelengths from the PW significantly increased the temperature in the RBCs and increased both depth of cure and the DC.
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http://dx.doi.org/10.1016/j.dental.2025.02.005 | DOI Listing |
Int J Oncol
October 2025
Department of Medical Laboratory, Hainan Cancer Hospital, Affiliated Cancer Hospital of Hainan Medical University, Haikou, Hainan 570312, P.R. China.
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy closely associated with Epstein‑Barr virus (EBV) infection. Although patients with early‑stage NPC can achieve a high cure rate through radiotherapy, recurrence and distant metastasis remain the primary causes of treatment failure in patients with advanced‑stage NPC. Circular RNA (circRNA) is a class of covalently closed non‑coding RNAs involved in multiple aspects of tumor biology.
View Article and Find Full Text PDFBMC Med Ethics
August 2025
Division of Infectious Diseases and Global Public Health, School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Introduction: Despite progress in antiretroviral therapy (ART), an effective cure for HIV remains out of reach. End-of-life (EOL) research studies involving individuals with a prognosis of six months or less offers an opportunity to advance cure science but has so far been limited to observational designs focused on HIV reservoirs. As interventional approaches at the EOL are now being considered, it is essential to assess their acceptability before moving forward.
View Article and Find Full Text PDFJ Transl Med
August 2025
Department of Gastroenterology, Affiliated Hospital of Jiangnan University, 214122, Wuxi city, Jiangsu Province, China.
Background: Inflammatory bowel disease (IBD) is a chronic nonspecific inflammatory disorder triggered by immune responses and genetic factors. Currently, there is no cure for IBD, and its etiology remains unclear. As a result, early detection and diagnosis of IBD pose significant challenges.
View Article and Find Full Text PDFJ Clin Exp Dent
July 2025
Universidad Privada San Juan Bautista, School of Stomatology, Lima, Peru.
Background: Preheating bulk-fill resins reduces their viscosity, facilitates their adaptation, and improves polymerization by accelerating the activity of photoinitiators. This would allow for more efficient application and deeper curing. The study's objective was to compare the surface microhardness and depth of cure of three bulk-fill composite resins with and without preheating.
View Article and Find Full Text PDF