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With the rapid urbanization and electrification in recent years, investment and construction in power infrastructure have been strengthened. Although it has a positive impact on economic development and energy distribution, the ecological and landscape impacts brought by the construction of related auxiliary facilities are often overlooked. To achieve a harmonious relationship between energy development and ecological protection, this study aims at the impacts of power transmission and transformation projects on ecological corridors and landscape connectivity. By coupling the morphological spatial pattern analysis and the least-cost path model, the regional ecological corridors are first constructed. In addition, the influences of power transmission and transformation projects on landscape connectivity can be evaluated and compared. This framework is verified through a case study of Shandong Province in China. The results indicated that power transmission and transformation projects had a significant impact on the migration resistance of landscapes, impeding the formation of ecological corridors for species. Additionally, these projects have exerted a pronounced cutting effect on landscapes, reducing ecological corridor permeability and landscape connectivity. It is crucial to preserve the habitats of major ecological sources while maintaining and developing the ecological nodes along the key ecological corridors. The findings contributed to the harmonization of regional energy planning and ecological protection, providing a reference for the future layout of transmission and transformation project construction and development.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862095 | PMC |
http://dx.doi.org/10.1038/s41598-025-91474-2 | DOI Listing |
Ren Fail
December 2025
Department of Nephrology, China-Japan Friendship Hospital, Beijing, China.
Objectives: In this study, we explored the mechanism by which DDIT4 influences the polarization phenotypic transformation of macrophages and inflammation through the regulation of mTOR signaling pathway, providing a new mechanism and target for the treatment of diabetic nephropathy.
Methods: The degree of inflammation and injury in renal tissues of diabetic kidney disease (DKD) animal model was evaluated using biochemical assays, renal pathology examinations, and Western blot tests. Podocytes and macrophages were isolated from renal tissues to observe the extent of podocyte injury and the quantity and polarization phenotype of macrophage infiltration.
Phytomedicine
August 2025
Cardiology Department, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China. Electronic address:
Background: Atherosclerosis (AS) is a leading risk factor for cardiovascular diseases globally, characterised by the accumulation of lipids and cholesterol in arterial walls, causing vascular narrowing and sclerosis along with chronic inflammation; this leads to increased risk of heart disease and stroke, significantly impacting patients' health. Danxia Tiaoban Decoction (DXTB), a traditional Chinese medicine (TCM) formula, has demonstrated positive clinical effects in treating AS; however, its mechanisms of action remain unclear.
Objective: To explore the potential mechanisms of action of DXTB in treating AS through multi-omics integration and experimental validation.
Spectrochim Acta A Mol Biomol Spectrosc
September 2025
Institute of Functional Molecules, Shenyang University of Chemical Technology, Shenyang 110142, China.
A new variety of nitrogen-doped carbon dots (NCDs) was produced using a hydrothermal synthesis method, based on propanedioic acid and barbituric acid as the sources of carbon and nitrogen. The NCDs were analyzed by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), Zeta Potential,X-ray Diffraction(XRD),Thermogravimetry-Derivative Thermogravimetry(TG-DTG),Fourier transform infrared spectroscopy (FTIR) and Fluorescence Lifetime. The characterization results indicate that NCDs possess an average diameter of approximately 2.
View Article and Find Full Text PDFBioorg Med Chem Lett
September 2025
Department of Chemistry, Taras Shevchenko National University of Kyiv, Kyiv 01601, Ukraine. Electronic address:
Phospholipid-derived nanocarriers represent a versatile and chemically customizable class of drug delivery systems that self-assemble into bilayered vesicles due to their intrinsic amphiphilicity. These systems can encapsulate both hydrophilic and hydrophobic drugs through non-covalent interactions and manipulation of lipid phase behavior. This review examines the molecular and supramolecular principles underlying the formation, stability, and functional performance of key phospholipid-based nanocarriers-including liposomes, transferosomes, ethosomes, invasomes, phytosomes, pharmacosomes, and virosomes.
View Article and Find Full Text PDFJ Hazard Mater
August 2025
Agro-Environmental Protection Institute, Ministry of Agriculture and Rural Affairs, Tianjin 300191, China. Electronic address:
Microplastics (MPs) and heavy metals (HMs), well-known environmental pollutants, have attracted widespread attention owing to their increasing threats. However, the interactions of MPs and chromium (Cr) at the microscale remain poorly understood, and the effects of environmental transformation on their toxicity remain controversial. The influences of light irradiation on their conversion were investigated using transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS).
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