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Peritonsillar abscess (PTA) is the most common deep neck infection, with well-known complications such as airway stenosis and aspiration pneumonia. However, death due to asphyxia caused by PTA is extremely rare in forensic research reports. Traditionally, the autopsy is the standard diagnostic method for pharyngeal lesions in forensic practice. The incorporation of postmortem computed tomography (PMCT) into the medicolegal death investigation has demonstrated unique diagnostic advantages for specific findings. In addition, virtual endoscopy (VE) shows great potential for supporting hollow organ assessment and postmortem diagnosis. Here, we report a case of asphyxial death due to airway obstruction caused by PTA. While autopsy, histopathological examination, and bacterial culture of fluid collected from the abscess effectively diagnosed PTA as the cause of airway obstruction leading to death, this case illustrates that PMCT combined with VE can be a valuable adjunct for in situ diagnosis.
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http://dx.doi.org/10.1111/1556-4029.70001 | DOI Listing |
Physiol Rep
September 2025
Cook Children's Health Care System - Exercise Respiratory Center, Prosper, Texas, USA.
Exercise-induced respiratory symptoms limit physical activity and sport performance in adolescents. Etiologies include exercise-induced bronchoconstriction, laryngeal obstruction, dysfunctional breathing, and in rarer cases, large airway obstruction and cardiac pathologies. Accurate diagnosis requires assessment during exercise that elicits the symptoms patients experience in the field.
View Article and Find Full Text PDFRespir Care
September 2025
Dr. Thomasian and Prof. Wunsch are affiliated with Department of Anesthesiology, Weill Cornell Medicine, New York, New York, USA.
Negative-pressure ventilation (NPV) is a form of noninvasive respiratory support in which an external subatmospheric pressure is applied to the thorax to facilitate lung expansion. Although largely supplanted by positive-pressure ventilation (PPV) in modern-day practice, NPV has garnered renewed interest as a potential noninvasive adjunct or alternative to PPV. Appropriate patient selection would be key, particularly in the ICU setting, where NPV is generally contraindicated in patients with severe upper airway obstruction, high oxygenation requirements, or absent airway reflexes.
View Article and Find Full Text PDFERJ Open Res
September 2025
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Background: Airway obstruction is a characteristic spirometric finding in asthma but the clinical significance of other abnormal spirometric patterns is less well described. We aimed to explore pre- and post-bronchodilator (BD) prevalences and clinical characteristics of preserved ratio impaired spirometry (PRISm), dysanapsis and airflow obstruction with low forced expiratory volume in 1 s (FEV) in children diagnosed with asthma.
Methods: We extracted specialist care data (clinical and spirometry) from the Swedish National Airway Register (n=3301, age 5-17 years).
Eur Arch Otorhinolaryngol
September 2025
Department of Otolaryngology Head And Neck Surgery, Far Eastern Memorial Hospital, No. 21, Section 2, Nan-Ya South Road, New Taipei City, Taiwan.
Introduction: Anterior glottic webs are epithelium-covered fibrous tissue formations at the anterior commissure, leading to synechiae between the bilateral vocal folds. They manifest with symptoms ranging from hoarseness to airway obstruction. However, treating anterior glottic webs are challenging due to their high recurrence rates.
View Article and Find Full Text PDFAm J Emerg Med
September 2025
University of South Carolina School of Medicine - Greenville, Greenville, SC, USA.
Total laryngectomy (TLE) results in the permanent separation of the respiratory and digestive tracts, requiring all airway interventions to occur exclusively via a neck stoma. Although airway obstruction in post-laryngectomy patients is uncommon, it can rapidly become fatal without prompt recognition and understanding of the altered anatomy. Here, we report the case of a patient with a recent TLE for squamous cell carcinoma, who presented to a rural Emergency Department (ED) in acute respiratory distress.
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