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Infectious bronchitis virus (IBV), an avian coronavirus, member of the genus Gammacoronavirus, poses significant threats to poultry health, causing severe respiratory, reproductive, and renal infections. The genetic diversity of IBV, driven by mutations, recombination and deletions, has led to the emergence of numerous serotypes and genotypes, complicating both diagnosis and control measures. Rapid and accurate diagnostic tools are essential for effective disease management and minimizing economic losses. Conventional diagnostic methods, such as PCR, virus isolation, and serological assays, are hindered by limitations in sensitivity, specificity, and turnaround time. In contrast, innovative biosensor platforms employing advanced detection mechanisms-including electrochemical, optical, and piezoelectric sensors-offer a transformative solution. These technologies provide portable, highly sensitive, and rapid diagnostic platforms for IBV detection. Beyond addressing the challenges of conventional methods, these biosensor-based approaches facilitate real-time monitoring and enhance disease surveillance. This review highlights the transformative potential of biosensors and their integration into diagnostic strategies for avian coronavirus infections, presenting them as a promising alternative for precise and efficient IBV detection.
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http://dx.doi.org/10.1016/j.virol.2025.110399 | DOI Listing |
Virus Evol
August 2025
College of Biology, Hunan Provincial Key Laboratory of Medical Virology, Hunan Research Center of the Basic Discipline for Cell Signaling, Hunan University, 52 Tianma Rd, Changsha, Hunan, 410012, China.
(γ-CoV) primarily infects poultry, wild birds, and marine mammals. The widespread distribution and circulation of γ-CoV in the ecological environment may lead to sustained transmission and economic loss. To better understand the diversity of γ-CoV in wild birds, we collected 482 wild-bird faecal samples from Yunnan, encompassing 14 bird species.
View Article and Find Full Text PDFJ Nanobiotechnology
August 2025
College of Veterinary Medicine, South China Agricultural University, Guangzhou, PR China.
Lipid nanoparticles-mRNA play important roles in SARS-CoV-2 infection control. Avian coronavirus infectious bronchitis virus (IBV) comprises eight genotypes with a lack of cross-protection, causing severe economic losses to the poultry industry. Using immunoinformatics methods, five consensus sequence antigens against prevalent IBV strains were designed.
View Article and Find Full Text PDFVaccines (Basel)
July 2025
College of Veterinary Medicine, South China Agricultural University, Guangzhou 510640, China.
: Infectious bronchitis virus (IBV) is a gammacoronavirus that causes a highly contagious disease in chickens and seriously endangers the poultry industry. The is a predominant lineage. However, no effective commercially available vaccines against this virus are available.
View Article and Find Full Text PDFViruses
August 2025
Instituto de Patología Animal, Universidad Austral de Chile, Campus Isla Teja, Edificio BID C 3° Piso, Valdivia 5090000, Chile.
Infectious bronchitis virus (IBV) remains a major threat to poultry health worldwide due to frequent genetic changes mainly driven by recombination and limited cross-protection between genotypes. In this study, we analyzed IBV strains collected from clinical outbreaks in Chile between 1986 and 2021 to assess the long-term impacts of live-attenuated vaccines (Massachusetts and 4/91) on viral evolution. Phylogenetic analysis of the S1 and N genes revealed four major lineages circulating in Chile-GI-1, GI-13, GI-16, and a novel monophyletic clade we propose as GI-31.
View Article and Find Full Text PDFViruses
July 2025
Facultad de Ciencias de la Salud, Carrera de Medicina Veterinaria, Universidad de Las Américas, Antigua Vía a Nayón S/N, Quito EC 170124, Ecuador.
Enteric diseases represent one of the main causes of morbidity and mortality in poultry production, especially in turkeys (), significantly affecting the profitability of the sector. Turkey enteric complex (PEC) is a multifactorial syndrome characterized by diarrhea, stunting, poor feed conversion, and increased mortality in young turkeys. Its aetiologia includes multiple avian enteric viruses, including astrovirus, rotavirus, reovirus, parvovirus, adenovirus, and coronavirus, which can act singly or in co-infection, increasing clinical severity.
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