Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Using new materials to improve detection accuracy and efficiency is important to broaden the application of immunoassay sensors. Among numerous materials for improving sensors, chitosan, as a natural polysaccharide, has excellent biocompatibility, mechanical adjustability, stimulation sensitivity and porous structure, which holds significant potential for enhancing the performance of immunoassay sensors. However, at present, there are few systematic reviews on the application of chitosan in immune sensors. In this paper, the principle of immunoassay is discussed systematically, we reviewed the recent development of chitosan enhancement strategies in various immunoassay sensors, including surface plasmon resonance immunoassay sensors, colorimetric immunoassay sensors, electrochemical immunoassay sensor, electrochemical luminescence immunoassay sensors are reviewed. Focused on the theoretical basis of improving sensor performance in immunoassay by use chitosan, as well as the various functions and applications of chitosan, and discussed how to solve the challenges of immunoassay sensors by using chitosan and the future research trend. By providing a robust foundation for the development of more efficient detection platforms, it provides insights for advancing the use of chitosan in the detection of complex biological samples. This is crucial for promoting the widespread application of immunoassay sensors with high performance in clinical diagnosis, environmental monitoring and food safety.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.carbpol.2024.123024 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Low-potential pyrene-coordinated MOFs and CoSOH nanosheets: An electrochemiluminescence energy resonance transfer system for aflatoxin B1 detection.
Anal Chim Acta
November 2025
The Key Lab of Health Chemistry & Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering & Materials Science, Soochow University, Suzhou, 215123, PR China; Center of Self-Propelled Nanotechnologies, Suzhou Industrial Park Institute of Services Outsourcing, Suzhou, 215123, PR China
Background: Of the mycotoxins, aflatoxin is the most significant. The detection of aflatoxin B1 (AFB1) is crucial for ensuring food safety, as this highly carcinogenic toxin readily contaminates crops such as grains and nuts, and timely detection can effectively prevent associated health risks. The selection of luminophores is of paramount importance in the detection of ECL (electrochemiluminescence).
View Article and Find Full Text PDFA β-cyclodextrin/AuNPs@MWCNT/chitosan-hydrogel-based 3D stochastic sensor for simultaneous determination of vascular cell adhesion molecule-1, interleukin-6, and natriuretic peptide C-type in whole blood samples.
Mikrochim Acta
September 2025
National Research and Development Institute for Chemistry and Petrochemistry ICECHIM, 202 Splaiul Independentei Street, 060021, Bucharest, Romania.
Molecular recognition and determination of vascular cell adhesion molecule-1 (VCAM-1), interleukin-6 (IL-6), and natriuretic peptide C-type (NPPC) are essential for the early prognosis and diagnosis of cardiovascular diseases, especially in young obese populations. Highly sensitive and selective devices characterized by low Limits of quantification are required for their determination in whole blood. Therefore, a 3D stochastic sensor was developed by immobilizing a chitosan hydrogel onto a carbon paste electrode (used as the support matrix for the hydrogel), which was subsequently modified with gold nanoparticles, multi-walled carbon nanotubes, and β-cyclodextrin (β-CD/AuNPs@MWCNT/CS/CPE).
View Article and Find Full Text PDFLigand Engineering-Based High-Efficiency Photothermal Sensors Powered Sensitive Lateral Flow Immunoassay Platform.
Anal Chem
September 2025
State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang330047, China.
The photothermal lateral flow immunoassay (LFIA) has garnered considerable attention, owing to its suitability for on-site quantitative detection. Furthermore, it has distinct advantages in further constructing sensitive detection methods for low-concentration targets. In this study, we employed a ligand engineering strategy to synthesize Fe-chelated quinone nanoparticles (FQNPs).
View Article and Find Full Text PDFElectrochemical detection of cortisol in sweat for sports performance analysis using graphene oxide-silicon carbide nanocomposites.
Mikrochim Acta
September 2025
College of Medical Technology, Shaanxi University of Chinese Medicine, Xianyang, 712000, Shaanxi, China.
An advanced electrochemical immunosensor platform was designed for the precise quantification of cortisol. The sensor design integrates graphene oxide-silicon carbide (GO-SiC) nanocomposites onto a glassy carbon electrode (GCE). Denatured bovine serum albumin (d-BSA) and an anti-cortisol antibody were immobilized on the GO-SiC/GCE surface as part of the immunosensor's design.
View Article and Find Full Text PDFA review of magnetic particles as separation tools in electrochemical detection of Biomarkers: Insights from COVID-19.
Anal Chim Acta
October 2025
Department of Chemistry, Federal University of São Carlos-UFSCar, Rod. Washington Luís km 235 - São Carlos, SP, 13565-905, Brazil. Electronic address:
Background: Magnetic particles (MPs) are widely used in bioanalytical systems to quickly separate specific targets from complex samples using a magnetic field. MPs can be easily functionalized with bioreceptors to capture, separate, and concentrate biomarkers like proteins, oligonucleotides, and cells. Combining MPs-separation capabilities with electrochemical sensors can greatly enhance the sensitivity of these devices, helping achieve ultralow limits of detection for biomarkers.
View Article and Find Full Text PDF