98%
921
2 minutes
20
This retrospective study evaluated two groups: patients receiving RFA for PVI, posterior wall isolation, mitral isthmus, and coronary sinus (CS) ablation with adjunctive VOM ethanol injection (VOM/RFA ALL (N = 53)), and patients receiving PVI with PFA using pentaspline catheter followed by mitral isthmus and CS ablation with RFA (PFA PV + PW/RFA MITRAL (N = 12)). We hypothesized that PFA for pulmonary vein isolation (PVI) facilitates mitral block without adjunctive vein of Marshall (VOM) ethanol injection. Mitral block was achieved in 92.5% of VOM/RFA ALL patients and 83.3% of the PFA PV + PW/RFA MITRAL group (p = 0.31). Endocardial ablation time of the mitral isthmus and RF applications required to achieve a complete block were significantly shorter in the VOM/RFA ALL group (208 s vs 356 s, p < 0.01 and 14.5 vs 24.0, p < 0.01, respectively). Adjunctive VOM ethanol injection appears to still have a role for facilitation of mitral isthmus block in the new era of PFA.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s10840-024-01963-z | DOI Listing |
Heart Rhythm
September 2025
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China. Electronic address:
Background: The effectiveness of ethanol infusion of the vein of Marshall (EIVOM) for persistent atrial fibrillation (AF) in patients with mitral valve replacement (MVR) remains to be determined.
Objectives: This study investigated the effectiveness and safety of EIVOM in catheter ablation of persistent AF in patients with MVR.
Methods: This is a retrospective case-control study.
J Cardiovasc Electrophysiol
September 2025
Pacing & Electrophysiology Unit, Cardiology Department, Coimbra's Hospital and University Center, Coimbra, Portugal.
Background: Pulmonary vein isolation (PVI) is the cornerstone of catheter ablation (CA) for atrial fibrillation (AF), yet outcomes remain suboptimal in persistent AF patients. Ethanol infusion in the vein of Marshal (VoM), an embryological remnant implicated in AF pathogenesis, may enhance ablation efficacy.
Objective: To evaluate the effectiveness of VoM ethanol infusion in patients with persistent AF.
Circ Arrhythm Electrophysiol
August 2025
Texas Cardiac Arrhythmia Institute, St David's Medical Center, Austin, TX (V.M.L.F., S.M., C.G., E.Z., N.P., P.G.T., W.B., J.D.B., R.H., A.A.-A., L.D.B., A.N.).
Background: The safety and efficacy of pulsed field ablation for pulmonary vein and posterior wall isolation in atrial fibrillation ablation are well established; however, evidence regarding its use in extra-pulmonary vein areas remains limited. The aim of this study was to assess the feasibility and durability of pulsed field ablation for coronary sinus (CS) and left atrial appendage (LAA) isolation and mitral isthmus (MI) ablation.
Methods: We analyzed data from consecutive patients who underwent repeat atrial fibrillation ablation with pulsed field ablation between February and October 2024.
Turk Kardiyol Dern Ars
August 2025
Department of Cardiology, Hacettepe University, Faculty of Medicine, Ankara, Türkiye.
Transcatheter aortic valve implantation (TAVI) has proven to be a safe and effective method, especially in patients with aortic stenosis whose surgical risk score is moderate to high. One of the possible complications after TAVI is bradyarrhythmia resulting from high-grade atrioventricular block. Some patients in this situation may require permanent pacemaker (PM) implantation.
View Article and Find Full Text PDFAtrial fibrillation (AF) originating from the left atrial posterior wall recurred repeatedly, resulting in immediate recurrence of AF (IRAF). Ethanol infusion into the vein of Marshall (VOM) successfully terminated the AF and simultaneously achieved complete mitral isthmus block. This dual effect underscores the potential utility of VOM ethanol infusion not only for mitral isthmus ablation but also for targeting non-pulmonary vein (non-PV) triggers in complex AF cases.
View Article and Find Full Text PDF