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Thoracic tracheal tumors are relatively rare in routine clinical practice. Though surgery is the preferred management choice, acute presentation is challenging for the surgeon and the anesthetist. In this study, we discuss the role of the percutaneous trans-tracheal endoscopic approach (PTTEA) in the modern era of minimally invasive surgery. Its indications, advantages, complications, and anesthetic options are enumerated. A retrospective review was performed of patients with thoracic tracheal lesions treated in our department between 2015 and 2022. A total of 16 patients underwent PTTEA in an emergency after a failed fiberoptic or transoral approach and were included in the review. Twelve patients were ventilated by intermittent apnea, and four had a Cardiopulmonary bypass. Amongst the 16 patients, nine had benign, and seven had malignant pathologies. All the benign lesions were excised completely, and patients were de-cannulated, except for one case with disseminated respiratory papillomatosis. Malignant lesions underwent debulking of the lesions for acute respiratory distress, followed by initiation of adjuvant therapy. PTTEA is an effective alternative to traditional fiberoptic or rigid bronchoscopy techniques for selected patients for whom minimally invasive techniques fail. The advantages of the approach include better surgical access, hemostasis, and airway control, resulting in reduced operative time and minimal complications.
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http://dx.doi.org/10.1007/s12070-024-05069-w | DOI Listing |
Ann Thorac Surg
September 2025
Department of Surgery, Division of Thoracic Surgery, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung, Taiwan 40705, ROC.
Airway stents provide symptomatic relief in malignant central airway stenosis, but carry the risk of migration, which may result in potentially lethal stent ingestion. A 22-year-old man underwent hybrid stent placement for tracheobronchial stenosis caused by an undiagnosed large mediastinal mass. Within 3 weeks after placement, following initial chemotherapy for provisionally diagnosed B-cell lymphoma, the stent migrated and was ingested.
View Article and Find Full Text PDFZhonghua Nei Ke Za Zhi
September 2025
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
To analyze the clinical characteristics of 14 patients with severe autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A). A retrospective analysis was conducted on the clinical data of 14 patients diagnosed with severe GFAP-A in Xuanwu Hospital, Capital Medical University, between July 2023 and September 2024. (1) Fourteen patients were included in the study, including 11 males and 3 females, aged 15-66 years (average: 39±13 years).
View Article and Find Full Text PDFWorld J Clin Oncol
August 2025
Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
Background: Tracheoesophageal fistula (TEF) is a life-threatening complication of advanced esophageal squamous cell carcinoma (ESCC). Cervical ESCC is rare and frequently diagnosed at an advanced stage. Managing cervical esophageal cancer (CEC) is challenging, requiring intervention by a multidisciplinary team (MDT) and innovative surgical management.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Endoscopy Center, Shaanxi Provincial Cancer Hospital Affiliated to Xi'an Jiaotong University, No. 309 Yanta West Road, Xi'an City, Xi'an, Shaanxi, 710061, China.
Tracheoesophageal fistula (TEF) represents a pathological connection between the trachea and esophagus, classified into congenital and acquired categories. Congenital TEF arises from embryological malformations, often coexisting with esophageal atresia (EA), while acquired TEF primarily stems from malignancies, radiotherapy, or trauma. This condition disrupts normal anatomical functions, leading to significant clinical issues, such as aspiration, respiratory infections, and malnutrition.
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