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http://dx.doi.org/10.1016/j.athoracsur.2025.08.029 | DOI Listing |
Cell Mol Immunol
September 2025
Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China.
Anti-tumor necrosis factor (TNF) therapy for inflammatory bowel disease (IBD) is hampered by issues of nonresponse and resistance, highlighting the urgent need for alternative or complementary treatments. Our study revealed significant upregulation of taurine in the intestinal tissues of IBD patients, which was inversely related to the severity of the disease. A key discovery was that TNF directly induced taurine synthesis in intestinal epithelial cells and increased the production of angiogenin, a nuclease that degrades mitochondrial RNA, which is known to amplify inflammatory responses.
View Article and Find Full Text PDFJ Neurosci
September 2025
Center for Studies in Behavioural Neurobiology, Department of Psychology, Concordia University, Montreal, QC, Canada, H4B 1R6
Adaptive behavior depends on a dynamic balance between acquisition and extinction memories. Male and female rodents differ in extinction learning rates, suggestion potential sex-based differences in this balance. In males, deletion of extinction-recruited neurons in the central nucleus (CN) of the amygdala impairs extinction retrieval, shifting behavior toward acquisition (Lay et al.
View Article and Find Full Text PDFBioresour Technol
September 2025
College of Forestry, Beijing Forestry University, Beijing 100083, PR China. Electronic address:
The timing of microbial inoculation is a decisive factor influencing both the efficiency and quality of green waste (GW) composting. This study evaluated the effects of applying a self-developed lignocellulose-degrading compound microbial inoculum at different composting phases (mesophilic, thermophilic, and cooling) compared to a commercial Effective Microorganisms agent. Thermophilic-phase inoculation (T2) was most effective by enhancing the complementary metabolic functions between strains, thus establishing an efficient lignocellulose degradation system.
View Article and Find Full Text PDFBackground And Aims: Trait-based approaches have advanced our understanding of plant strategies, yet they often focus on leaf-level traits, overlooking the functional roles of stem anatomy and twig characteristics. We investigated intraspecific trait variation in Salix flabellaris, an alpine dwarf shrub, along climatic gradients in the Himalayas. Our goal was to identify distinct axes of trait variation related to stem, twig, and leaf traits, assess their environmental drivers, and evaluate population-specific growth responses to recent climate change.
View Article and Find Full Text PDFTurkiye Parazitol Derg
September 2025
Department of Medical Physics, Faculty of Paramedicine, Arak University of Medical Sciences, Arak, Iran.
Objective: Drug resistance in poses a significant challenge, prompting the need for alternative treatments. This research aimed to explore the combined treatment of chemical or phytomedicines and microwaves radiation.
Methods: The strain was cultivated on non-nutrient agar.