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http://dx.doi.org/10.1038/s41375-024-02449-7 | DOI Listing |
Nature
September 2025
Department of Physics, Harvard University, Cambridge, MA, USA.
Quantum simulations of many-body systems are among the most promising applications of quantum computers. In particular, models based on strongly correlated fermions are central to our understanding of quantum chemistry and materials problems, and can lead to exotic, topological phases of matter. However, owing to the non-local nature of fermions, such models are challenging to simulate with qubit devices.
View Article and Find Full Text PDFNature
September 2025
Centre for Evolution and Cancer, Institute of Cancer Research, London, UK.
Cancer development and response to treatment are evolutionary processes, but characterizing evolutionary dynamics at a clinically meaningful scale has remained challenging. Here we develop a new methodology called EVOFLUx, based on natural DNA methylation barcodes fluctuating over time, that quantitatively infers evolutionary dynamics using only a bulk tumour methylation profile as input. We apply EVOFLUx to 1,976 well-characterized lymphoid cancer samples spanning a broad spectrum of diseases and show that initial tumour growth rate, malignancy age and epimutation rates vary by orders of magnitude across disease types.
View Article and Find Full Text PDFLangmuir
September 2025
College of Materials Science and Engineering, North University of China, Taiyuan 030051, PR China.
The oxygen evolution reaction (OER), a critical yet kinetically sluggish process in electrochemical water splitting, severely limits efficient hydrogen production. Herein, a simple one-step dynamic hydrogen bubble templated electrodeposition technique is used to prepare a self-supported 3D porous NiCuFeP catalyst with outstanding OER performance. In 1.
View Article and Find Full Text PDFMicrobes Environ
September 2025
Sustainable Process Engineering Center, Department of Chemical Engineering, Faculty of Engineering, Universiti Malaya.
Nitrifying communities in activated sludge play a crucial role in biological nitrogen removal processes in municipal wastewater treatment plants. While extensive research has been conducted in temperate regions, limited information is available on nitrifiers in tropical regions. The present study investigated all currently known nitrifying communities in two full-scale municipal wastewater treatment plants in Malaysia operated under low-dissolved oxygen (DO) (0.
View Article and Find Full Text PDFBiochim Biophys Acta Biomembr
September 2025
Department of Chemistry, University of Toronto, Canada; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, L5L 1C6, Canada. Electronic address:
In 1987 Seelig and colleagues proposed that the phosphocholine headgroup of phosphatidylcholine behaved as a universal sensor of surface electrostatic charge, both cationic and anionic, in lipid bilayers (J. Seelig, P.M.
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