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Accurate pneumoconiosis staging is key to early intervention and treatment planning for pneumoconiosis patients. The staging process relies on assessing the profusion level of small opacities, which are dispersed throughout the entire lung field and manifest as fine textures. While conventional convolutional neural networks (CNNs) have achieved significant success in tasks such as image classification and object recognition, they are less effective for classifying fine-grained medical images due to the need for global, orderless feature representation. This limitation often results in inaccurate staging outcomes for pneumoconiosis. In this study, we propose a deep texture encoding scheme with a suppression strategy designed to capture the global, orderless characteristics of pneumoconiosis lesions while suppressing prominent regions such as the ribs and clavicles within the lung field. To further enhance staging accuracy, we incorporate an ordinal label distribution to capture the ordinal information among profusion levels of opacities. Additionally, we employ supervised contrastive learning to develop a more discriminative feature space for downstream classification tasks. Finally, in accordance with standard practices, we evaluate the profusion levels of opacities in each subregion of the lung, rather than relying on the entire chest X-ray image. Experimental results on the pneumoconiosis dataset demonstrate the superior performance of the proposed method confirming its effectiveness for accurate pneumoconiosis staging.
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http://dx.doi.org/10.3389/fmed.2024.1440585 | DOI Listing |
Front Med (Lausanne)
July 2025
Department of Radiology, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing, China.
Objective: This study aims to develop a machine learning (ML) model that integrates computed tomography (CT) radiomics with clinical features to predict the progression of pulmonary interstitial fibrosis in patients with coalworker pneumoconiosis (CWP).
Methods: Clinical and imaging data from 297 patients diagnosed with CWP at The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College between December 2021 and December 2023 were analyzed. Of these patients, 170 developed pulmonary interstitial fibrosis over a 3-year follow-up and were classified as the progression group, while 127 patients showed stable conditions and were classified as the stable group.
J Med Life
June 2025
Department of Dental Technology, Faculty of Midwifery and Nursing, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Dental professionals face numerous occupational health risks that can significantly impact their well-being and career longevity. This scoping review synthesizes current evidence on the prevalence, risk factors, and prevention strategies for major occupational health issues in dentistry. The article selection process adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
View Article and Find Full Text PDFRespir Med
October 2025
Department of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, China; The Medical Basic Research Innovation Center of Airway Disease in North China, Ministry of Education of China, China; JLU-USYD Joint Research Center for Respiratory Diseases, China; Jilin P
Background: Harsh workplace can include very cold, hot, and dusty workplaces, as well as exposure in the workplace with chemicals and other fumes, cigarette smoke, and diesel exhaust. There is a shortage of genetic evidence regarding the impact of harsh workplaces on respiratory health.
Objective: This study aims to investigate the genetic association between harsh workplace and respiratory diseases.
J Chromatogr B Analyt Technol Biomed Life Sci
October 2025
West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China. Electronic address:
Silicosis is characterized by the formation of fibrotic lesions due to altered collagen synthesis, in which amino acids play a crucial role. However, targeted metabolomics studies of serum amino acids in silicosis patients remain limited. Herein, we developed a specific serum amino acid metabolomics assay for identifying differential amino acids as biomarkers, providing a sensitive and reliable basis for diagnosing silicosis.
View Article and Find Full Text PDFEur Radiol
July 2025
Department of Radiology, Guiqian International General Hospital, Guiyang, People's Republic of China.
Objectives: Accurately quantify pulmonary iron oxide by dual-energy CT (DECT) and evaluate its diagnostic potential in arc-welders' pneumoconiosis (AWP).
Materials And Methods: This prospective, single‑center diagnostic accuracy study (April 2024 to October 2024) included three groups: welders, mimic-imaging, and healthy controls. DECT quantified whole-lung FeO density (mg/cm³) [D] and total FeO mass (mg) [Total-FeO].