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Minimally invasive access cavities have been proposed in the last decade to reduce tooth tissue loss during endodontic treatment and mitigate compromised fracture resistance of endodontically treated teeth. Fracture resistance of molars with different types of access cavity design may be affected by restorative materials and aging. Insufficient literature data exist on the effect of cavity design and type of restorative materials on restorative aspects such as material adaptation or photo-polymerization in restricted access cavities. This study analyses quality of polymerization, material adaptation and fracture resistance of molars with different types of access cavities restored with glass-ionomer, high-viscosity fiber-reinforced bulk-fill and nanofilled resin composite. Plastic molar teeth with truss (TREC) and traditional endodontic access cavity (TEC) were restored with nanofilled composite (Filtek Supreme), glass-ionomer Fuji IX and Filtek or fiber-reinforced everX Posterior and Filtek. Porosity was determined using microcomputer tomography and the degree of conversion of resin-based materals using micro-Raman spectroscopy. Human molars prepared and restored in the same way were used for fracture resistance testing at baseline and after thermocycling. The results demonstrate that high-viscosity fiber-reinforced composite was difficult to adapt in TREC cavity leading to greater porosity than Filtek or Fuji. TREC design did not affect composite polymerization and led to higher fracture resistance of restored molars compared to TEC but also more unrestorable fractures.
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http://dx.doi.org/10.1038/s41598-024-72643-1 | DOI Listing |
J Am Geriatr Soc
September 2025
Global Health Research Center, Duke Kunshan University, Kunshan, Jiangsu, China.
Background: Physical resilience-the ability to withstand, recover, or adapt after a stressor-is critical in older adults facing acute insults. We conceptualize physical resilience to comprise two distinct but related components: resistance (immediate physiological response to the stressor) and recovery (subsequent health changes). These two components were used to evaluate how individuals respond to hip fracture-a common and severe geriatric stressor.
View Article and Find Full Text PDFOsteoporos Int
September 2025
Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400037, China.
Diabetes and osteoporosis are common chronic diseases worldwide, and there is a complex pathological relationship between the two. Due to hyperglycemia, insulin resistance, and accumulation of advanced glycation end products (AGEs), diabetic patients often show a higher risk of fractures. At the same time, chronic low-grade inflammation and oxidative stress caused by diabetes also play an important role in the occurrence of osteoporosis, disrupting the balance of bone remodeling.
View Article and Find Full Text PDFJ Prosthodont
September 2025
Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Purpose: This study aimed to evaluate the inherent and after cyclic loading fracture strength of implant-supported cantilevered fixed prostheses fabricated from recently introduced additively manufactured (AM) and subtractively manufactured (SM) materials, considering variations in prosthesis height.
Materials And Methods: Three cylinder-shaped master files (20 mm long and 11 mm wide) with varying heights (7, 11, and 15 mm) and a titanium-base (Ti-base) abutment space were designed. These designs were used to fabricate a total of 144 specimens with two AM resins indicated for definitive use (Crowntec; AM-CT and Flexcera Smile Ultra+; AM-FS), one high-impact polymer composite (breCAM.
Infect Drug Resist
August 2025
Department of Orthopedic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, People's Republic of China.
Background: Surgical site infection (SSI) after surgery can cause serious sequelae in patients with tibial plateau fractures. This study aims to report the incidence and characteristics of SSI and to investigate the risk factors of SSI in adult patients with closed tibial plateau fracture, especially the relationship between SSI and preoperative hypoalbuminemia.
Methods: We retrospectively reviewed the records of adult patients with closed tibial plateau fracture who were treated at our institution from January 2016 to December 2022.
Oncol Res
September 2025
Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Background: Multiple myeloma (MM) remains a formidable clinical challenge due to its high relapse rate and resistance to existing therapies. Estrogen-related receptor gamma (ERRγ), a nuclear receptor critical for cellular energy metabolism, has been implicated in various cancers. but its role in MM remains unclear.
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